A quick method to calculate QTL confidence interval

Journal of Genetics

Volumn 90, Issue 2, 2011, Pages 355-360

  Li, Hengde ^a  

^a SOUTH CHINA SEA FISHERIES RESEARCH INSTITUTE   (China)

Author keywords

confidence interval; quantitative trait loci

Indexed keywords

ALGORITHM; ANIMAL; ARTICLE; BIOLOGICAL MODEL; COMPUTER SIMULATION; CONFIDENCE INTERVAL; GENETIC LINKAGE; GENETICS; QUANTITATIVE TRAIT LOCUS; STATISTICAL MODEL; SWINE;

ALGORITHMS; ANIMALS; COMPUTER SIMULATION; CONFIDENCE INTERVALS; GENETIC LINKAGE; LIKELIHOOD FUNCTIONS; MODELS, GENETIC; QUANTITATIVE TRAIT LOCI; SWINE;

EID: 80053132064     PISSN: 00221333     EISSN: 09737731     Source Type: Journal    
DOI: 10.1007/s12041-011-0077-7     Document Type: Article

References (16)

1. Bennewitz J., Reinsch N. and Kahn E. 2002 Improved confidence intervals in quantitative trait loci mapping by permutation bootstrapping. Genetics160, 1673-1686.
2. Darvasi A. and Soller M. 1997 A simple method to calculate resolving power and confidence interval of QTL map location. Behav. Genet. 27, 125-132.
3. Dupuis J. and Siegmund D. 1999 Statistical methods for mapping quantitative trait loci from a dense set of markers. Genetics151, 373-386.
4. Haldane J. B. S. 1919 The combination of linkage values, and the calculation of distance between the loci of linked factors. J. Genet. 8, 299-309.
5. Lander E. S. and Botstein D. 1989 Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics121, 185-199.
6. Li H. D., Lund M. S., Christensen O. F., Gregersen V. R., Henckel P. and Bendixen C. 2010 Quantitative trait loci analysis of swine meat quality traits. J. Anim. Sci. 88, 2904-2912.
7. Lynch M. and Walsh B. 1998 Genetics and analysis of quantitative traits. Sinauer Associates, Sunderland, MA, 01375 U. S. A.
8. Mackay T. F. C. 2001 The genetic architecture of quantitative traits. Annu. Rev. Genet. 35, 303-339.
9. Mangin B., Goffinet B. and Rebai A. 1994 Constructing confidence intervals for QTL location. Genetics138, 1301-1308.
10. Manichaikul A., Dupuis J., Sen S. and Broman K. W. 2006 Poor performance of bootstrap confidence intervals for the location of a quantitative trait locus. Genetics174, 481-489.
11. R Development Core Team 2010 R: a language and environment for statistical computing. Reference Index Version 2. 12. 0. R Foundation for Statistical Computing, Vienna, Austria (http://www. R-project. org).
12. Sugiyama F., Churchill G. A., Higgins D. C., Johns C., Makaritsis K. P., Gavras H. and Paigen B. 2001 Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci. Genomics71, 70-77.
13. Visscher P. M., Thompson R. and Haley C. S. 1996 Confidence intervals in QTL mapping by bootstrapping. Genetics143, 1013-1020.
14. Walling G. A., Visscher P. M. and Haley C. S. 1998 A comparison of bootstrap methods to construct confidence intervals in QTL mapping. Genet. Res. 71, 171-180.
15. Walling G. A., Haley C. S., Perez-Enciso M., Thompson R. and Visscher P. M. 2002 On the mapping of quantitative trait loci at marker and non-marker locations. Genet. Res. 79, 97-106.
16. Weller J. I. and Soller M. 2004 An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design. Theor. Appl. Genet. 109, 1224-1229.