Effect of puerarin on retinal pigment epithelial cells apoptosis induced partly by peroxynitrite via fas/fasl pathway

International Journal of Ophthalmology

Volumn 3, Issue 4, 2010, Pages 283-287

  Hao, Li Na ^a   Zhang, Yan Qing ^b   Shen, Yu Hua ^c   Wang, Zhi Yun ^b   Wang, Yan Hua ^b   Zhang, Hai Fang ^a   He, Shou Zhi ^d  

^a HEBEI GENERAL HOSPITAL   (China)

^b Chengde Electric Power Supply Corporation   (China)

^c Handan Eye Hospital   (China)

^d Chinese PLA Hospital   (China)

Author keywords

Cell signal; Complement; Oxidative; Puerarin; Retinal pigment epithelial cells

Indexed keywords

EID: 80053099098     PISSN: 22223959     EISSN: 22274898     Source Type: Journal    
DOI: 10.3980/j.issn.2222-3959.2010.04.01     Document Type: Article

References (17)

1. Pacher P, Szabó C. Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes. Curr Opin Pharmacol. 2006;6(2):136-141.
2. Hanneken A, Lin FF, Johnson J, Maher P. Flavonoids protect human retinal pigment epithelial cells from oxidative-stress-induced death. Invest Ophthalmol Vis Sci. 2006;47(7):3164-3177.
3. Bucolo C, Ward KW, Mazzon E, Cuzzocrea S, Drago F. Protective effects of a coumarin derivative in diabetic rats. Invest Ophthalmol Vis Sci. 2009;50(8):3846-3852.
4. Hao LN, He SZ, Luo XM, Ma QM, Mao QY, Ling Y L. Effect of puerarin on prevention of peroxynitrite-induced damage to the LEC and Fas/FasL apoptosis signal in culture. Chin J Ophthalmol. 2008;44(2):163-168.
5. Hao LN, He SZ, Luo XM, Mao QY, Ling Y L. Puerarin decreases lens epithelium cell apoptosis induced partly by peroxynitrite in diabetic rats. Acta Physiologic Sinica. 2006;58(6):584-592.
6. Korkolopoulou P, Saetta AA, Levidou G, Gigelou F, Lazaris A, Thymara I, Scliri M, Bousboukea K, Michalopoulos NV, Apostolikas N, Konstantinidou A, Tzivras M, Patsouris E. c-FLIP expression in colorectal carcinomas: association with Fas/FasL expression and prognostic implications. Histopathol. 2007;51(2):150-156.
7. Zacks DN, Boehlke C, Richards AL, Zheng QD. Role of the Fas-signaling pathway in photoreceptor neuroprotection. Arc Ophthalmol. 2007;125(10):1389- 1395.
8. Semkova I, Fauser S, Lappas A, Smyth N, Kociok N, Kirchhof B, Paulsson M, Poulaki V, Joussen AM. Overexpression of FasL in retinal pigment epithelial cells reduces choroidal neovascularization. FASEB. 2006;20(10):1689-1691. [PubMed
9. Lukinova N, Iacovelli J, Dentchev T, Wolkow N, Hunter A, Amado D, Ying GS, Sparrow JR, Dunaief JL. Iron chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli. Invest Ophthalmol Vis Sci. 2009;50(3):1440-1447.
10. Ferrington DA, Tran TN, Lew KL, Van Remmen H, Gregerson DS. Different death stimuli evoke apoptosis via multiple pathways in retinal pigment epithelial cells. Exp Eye Res. 2006;83(3):638-650.
11. McKechnie N M, King BC, Fletcher E, Braun G. Fas-ligand is stored in secretory lysosomes of ocular barrier epithelia and released with microvesicles. Exp Eye Res. 2006;83(2):304-314.
12. Kowluru RA, Chan PS. Oxidative stress and diabetic retinopathy. Exp Diabetes Res. 2007;20:436-443.
13. Fang IM, Yang CH, Yang CM, Chen MS. Comparative effects of fatty acids on proinflammatory gene cyclooxygenase 2 and inducible nitric oxide synthase expression in retinal pigment epithelial cells. Mol Nutr Food Res. 2009;53(6):739-750.
14. Kociok N, Joussen A M. Varied expression of functionally important genes of RPE and choroid in the macula and in the periphery of normal human eyes. Graefes Arch Clin Exp Ophthalmol. 2007;245(1):101-113.
15. Zhou J, Kim SR, Westlund BS, Sparrow JR. Complement activation by bisretinoid constituents of RPE lipofuscin. Invest Ophthalmol Vis Sci. 2009;50(3):1392-1399.
16. Vogt SD, Barnum SR, Curcio CA, Read RW. Distribution of complement anaphylatoxin receptors and membrane-bound regulators in normal human retina. Exp Eye Res. 2006;83(4):834-840.
17. Chen M, Muckersie E, Robertson M, Forrester JV, Xu H. Up-regulation of complement factor B in retinal pigment epithelial cells is accompanied by complement activation in the aged retina. Exp Eye Res. 2008;87(6):543-550.