Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 37, 2011, Pages 15174-15178

  Agnew, Christopher ^a   Borodina, Elena ^a   Zaccai, Nathan R ^a   Conners, Rebecca ^a   Burton, Nicholas M ^a   Vicary, James A ^a   Cole, David K ^b   Antognozzi, Massimo ^a   Virji, Mumtaz ^a   Brady, R Leo ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Atomic force microscopy; Bacterial adhesins; Small angle X ray scattering; X ray crystallography

Indexed keywords

ADHESIN; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; FIBRONECTIN; UNCLASSIFIED DRUG; USPA1 PROTEIN;

ARTICLE; ATOMIC FORCE MICROSCOPY; CELL ADHESION; CELL SURFACE; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ELECTRON MICROSCOPY; MORAXELLA CATARRHALIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RADIATION SCATTERING; THICKNESS;

ADHESINS, BACTERIAL; ANTIGENS, CD; BACTERIAL OUTER MEMBRANE PROTEINS; CELL ADHESION MOLECULES; CELL MEMBRANE; FIBRONECTINS; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MICROSCOPY, ATOMIC FORCE; MODELS, MOLECULAR; MORAXELLA (BRANHAMELLA) CATARRHALIS; PROTEIN BINDING; SCATTERING, SMALL ANGLE; X-RAY DIFFRACTION;

BACTERIA (MICROORGANISMS); MORAXELLA CATARRHALIS;

EID: 80053072203     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1106341108     Document Type: Article

References (23)

1. Karalus R, Campagnari A (2000) Moraxella catarrhalis: A review of an important human mucosal pathogen. Microbes Infect 2:547-559. (Pubitemid 30387209)
2. Hultgren SJ, et al. (1993) Pilus and nonpilus bacterial adhesins: Assembly and function in cell recognition. Cell 73:887-901. (Pubitemid 23165606)
3. Hoiczyk E, Roggenkamp A, Reichenbecher M, Lupas A, Heesemann J (2000) Structure and sequence analysis of Yersinia YadA and Moraxella UspAs reveal a novel class of adhesins. EMBO J 19:5989-5999.
4. Szczesny P, et al. (2008) Structure of the head of the Bartonella adhesin BadA. PLoS Pathog 4:e1000119.
5. Wells TJ, Tree JJ, Ulett GC, Schembri MA (2007) Autotransporter proteins: Novel targets at the bacterial cell surface. FEMS Microbiol Lett 274:163-172. (Pubitemid 47256260)
6. Cotter SE, Surana NK, St Geme JW, 3rd (2005) Trimeric autotransporters: A distinct subfamily of autotransporter proteins. Trends Microbiol 13:199-205. (Pubitemid 40603902)
7. Conners R, et al. (2008) The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil. EMBO J 27:1779-1789.
8. Edwards TE, et al. (2010) Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head. PLoS One 5:e12803.
9. Tan TT, Nordstrom T, Forsgren A, Riesbeck K (2005) The respiratory pathogen Moraxella catarrhalis adheres to epithelial cells by interacting with fibronectin through ubiquitous surface proteins A1 and A2. J Infect Dis 192:1029-1038. (Pubitemid 41266800)
10. Tan TT, Forsgren A, Riesbeck K (2006) The respiratory pathogen Moraxella catarrhalis binds to laminin via ubiquitous surface proteins A1 and A2. J Infect Dis 194:493-497. (Pubitemid 44162661)
11. Hill DJ, Edwards AM, Rowe HA, Virji M (2005) Carcinoembryonic antigen-related cell adhesion molecule (CEACAM)-binding recombinant polypeptide confers protection against infection by respiratory and urogenital pathogens. Mol Microbiol 55:1515-1527. (Pubitemid 40342076)
12. Senden TJ, Drummond KJ (1995) Surface chemistry and tip-sample interactions in atomic force microscopy. Colloids Surfaces A Physicochem Eng Asp 94:29-51.
13. Scholz T, et al. (2011) Processive behaviour of kinesin observed using micro-fabricated cantilevers. Nanotechnology 22:095707.
14. Dupres V, et al. (2005) Nanoscale mapping and functional analysis of individual adhesins on living bacteria. Nat Methods 2:515-520. (Pubitemid 41131157)
15. Lulevich V, Zimmer CC, Hong HS, Jin LW, Liu GY (2010) Single-cell mechanics provides a sensitive and quantitative means for probing amyloid-beta peptide and neuronal cell interactions. Proc Natl Acad Sci USA 107:13872-13877.
16. Nummelin H, et al. (2004) The Yersinia adhesin YadA collagen-binding domain structure is a novel left-handed parallel beta-roll. EMBO J 23:701-711. (Pubitemid 38418738)
17. Busby TF, et al. (1995) Heparin binding by fibronectin module III-13 involves six discontinuous basic residues brought together to form a cationic cradle. J Biol Chem 270:18558-18562.
18. Bloom L, Ingham KC, Hynes RO (1999) Fibronectin regulates assembly of actin filaments and focal contacts in cultured cells via the heparin-binding site in repeat III13. Mol Biol Cell 10:1521-1536. (Pubitemid 29230906)
19. McMichael JC, et al. (1998) Isolation and characterization of two proteins from Moraxella catarrhalis that bear a common epitope. Infect Immun 66:4374-4381. (Pubitemid 28402714)
20. Meng G, Surana NK, St Geme JW, 3rd, Waksman G (2006) Structure of the outer membrane translocator domain of the Haemophilus influenzae Hia trimeric autotransporter. EMBO J 25:2297-2304. (Pubitemid 44012213)
21. Koretke KK, Szczesny P, Gruber M, Lupas AN (2006) Model structure of the prototypical non-fimbrial adhesin YadA of Yersinia enterocolitica. J Struct Biol 155:154-161. (Pubitemid 44278639)
22. Abraham SN, Beachey EH, Simpson WA (1983) Adherence of Streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa to fibronectin-coated and uncoated epithelial cells. Infect Immun 41:1261-1268. (Pubitemid 13048605)
23. Simpson WAaB, Edwin H (1983) Adherence of group A streptococci to fibronectin on oral epithelial cells. Infect Immun 39:275-279.