Synthesis of a novel series of 1,2,3-triazole-containing artemisinin dimers with potent anticancer activity involving Huisgen 1,3-dipolar cycloaddition reaction

Synthesis

Volumn , Issue 19, 2011, Pages 3173-3179

  Saikia, Bishwajit ^a   Saikia, Partha Pratim ^a   Goswami, Abhishek ^a   Barua, Nabin C ^a   Saxena, Ajit K ^b   Suri, Nitasha ^b  

^a CSIR NORTH EAST INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

1,2,3 triazole; antimalarial; Artemisia annua; artemisinin; artemisinin dimer

Indexed keywords

1 ,3-DIPOLARCYCLOADDITION; 1,2,3-TRIAZOLE; ANTICANCER ACTIVITIES; ANTIMALARIAL; ARTEMISIA ANNUA; ARTEMISININ; CANCER CELL LINES; NOVEL SERIES; STRONG GROWTH; TERMINAL ALKYNE;

ACETYLENE; CELL CULTURE; CYCLOADDITION; NITROGEN COMPOUNDS;

SYNTHESIS (CHEMICAL);

1,2,3 TRIAZOLE CONTAINING ARTEMISININ DIMER DERIVATIVE; ANTINEOPLASTIC AGENT; ARTEMISININ; ARTEMISININ DERIVATIVE; ARTEMISININ DIMER; ARTEMISININ LACTOL; FLUOROURACIL; MITOMYCIN C; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; COLON CANCER; CONTROLLED STUDY; CYCLOADDITION; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; HUISGEN 1,3 DIPOLAR CYCLOADDITION; HUMAN; HUMAN CELL; LEUKEMIA; LIVER CANCER; LUNG CANCER;

EID: 80053052326     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1260157     Document Type: Article

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