-
2
-
-
77952300540
-
Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival
-
B. Escudier, J. Bellmunt, and S. Négrier Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival J Clin Oncol 28 2010 2144 2150
-
(2010)
J Clin Oncol
, vol.28
, pp. 2144-2150
-
-
Escudier, B.1
Bellmunt, J.2
Négrier, S.3
-
3
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
DOI 10.1056/NEJMoa060655
-
B. Escudier, T. Eisen, and W.M. Stadler Sorafenib in advanced clear-cell renal-cell carcinoma N Engl J Med 356 2007 125 134 (Pubitemid 46089673)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
4
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
DOI 10.1056/NEJMoa066838
-
G. Hudes, M. Carducci, and P. Tomczak Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma N Engl J Med 356 2007 2271 2281 (Pubitemid 46849157)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
Dutcher, J.4
Figlin, R.5
Kapoor, A.6
Staroslawska, E.7
Sosman, J.8
McDermott, D.9
Bodrogi, I.10
Kovacevic, Z.11
Lesovoy, V.12
Schmidt-Wolf, I.G.H.13
Barbarash, O.14
Gokmen, E.15
O'Toole, T.16
Lustgarten, S.17
Moore, L.18
Motzer, R.J.19
-
5
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
-
R.J. Motzer, B. Escudier, and S. Oudard Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial Lancet 372 2008 449 456
-
(2008)
Lancet
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
6
-
-
68949145218
-
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
-
R.J. Motzer, T.E. Hutson, and P. Tomczak Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma J Clin Oncol 27 2009 3584 3590
-
(2009)
J Clin Oncol
, vol.27
, pp. 3584-3590
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
7
-
-
77952318310
-
Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: Final results of CALGB 90206
-
2137-43
-
B.I. Rini, S. Halabi, and J.E. Rosenberg Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206 2137-43 J Clin Oncol 28 2010 2137 2143
-
(2010)
J Clin Oncol
, vol.28
, pp. 2137-2143
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
-
8
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
C.N. Sternberg, I.D. Davis, and J. Mardiak Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial J Clin Oncol 28 2010 1061 1068
-
(2010)
J Clin Oncol
, vol.28
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
-
10
-
-
77956227464
-
Phase 3 trial of everolimus for metastatic renal cell carcinoma
-
R.J. Motzer, B. Escudier, and S. Oudard Phase 3 trial of everolimus for metastatic renal cell carcinoma Cancer 116 2010 4256 4265
-
(2010)
Cancer
, vol.116
, pp. 4256-4265
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
11
-
-
58149337448
-
Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3
-
D.D. Hu-Lowe, H.Y. Zou, and M.L. Grazzini Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3 Clin Cancer Res 14 2008 7272 7283
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7272-7283
-
-
Hu-Lowe, D.D.1
Zou, H.Y.2
Grazzini, M.L.3
-
12
-
-
35448934762
-
Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: A phase II study
-
DOI 10.1016/S1470-2045(07)70285-1, PII S1470204507702851
-
O. Rixe, R.M. Bukowski, and M.D. Michaelson Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study Lancet Oncol 8 2007 975 984 (Pubitemid 47629888)
-
(2007)
Lancet Oncology
, vol.8
, Issue.11
, pp. 975-984
-
-
Rixe, O.1
Bukowski, R.M.2
Michaelson, M.D.3
Wilding, G.4
Hudes, G.R.5
Bolte, O.6
Motzer, R.J.7
Bycott, P.8
Liau, K.F.9
Freddo, J.10
Trask, P.C.11
Kim, S.12
Rini, B.I.13
-
13
-
-
80052991861
-
Axitinib second-line therapy for metastatic renal cell carcinoma (mRCC): Five-year (yr) overall survival (OS) data from a phase II trial
-
Abstract 4547
-
R.J. Motzer, T.d.L.M. Rouge, and A.L. Harzstark Axitinib second-line therapy for metastatic renal cell carcinoma (mRCC): Five-year (yr) overall survival (OS) data from a phase II trial J Clin Oncol 29 Suppl 2011 Abstract 4547
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Motzer, R.J.1
Rouge, D.T.L.M.2
Harzstark, A.L.3
-
14
-
-
70349388719
-
Phase II study of axitinib in sorafenib-refractory metastatic renal cell carcinoma
-
B.I. Rini, G. Wilding, and G. Hudes Phase II study of axitinib in sorafenib-refractory metastatic renal cell carcinoma J Clin Oncol 27 2009 4462 4468
-
(2009)
J Clin Oncol
, vol.27
, pp. 4462-4468
-
-
Rini, B.I.1
Wilding, G.2
Hudes, G.3
-
15
-
-
80052225008
-
Axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC): Results of phase III AXIS trial
-
Abstract 4503
-
B.I. Rini, B. Escudier, and P. Tomczak Axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC): results of phase III AXIS trial J Clin Oncol 29 Suppl 2011 Abstract 4503
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Rini, B.I.1
Escudier, B.2
Tomczak, P.3
-
16
-
-
80053008404
-
Patient-reported outcomes (PROs) in a phase III AXIS trial of axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC)
-
Abstract 4504
-
D. Cella, B. Escudier, and B.I. Rini Patient-reported outcomes (PROs) in a phase III AXIS trial of axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC) J Clin Oncol 29 Suppl 2011 Abstract 4504
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Cella, D.1
Escudier, B.2
Rini, B.I.3
-
17
-
-
79956281829
-
Patient-reported outcomes in a phase III study of everolimus versus placebo in patients with metastatic carcinoma of the kidney that has progressed on vascular endothelial growth factor receptor tyrosine kinase inhibitor therapy
-
J.L. Beaumont, Z. Butt, and J. Baladi Patient-reported outcomes in a phase III study of everolimus versus placebo in patients with metastatic carcinoma of the kidney that has progressed on vascular endothelial growth factor receptor tyrosine kinase inhibitor therapy Oncologist 16 2011 632 640
-
(2011)
Oncologist
, vol.16
, pp. 632-640
-
-
Beaumont, J.L.1
Butt, Z.2
Baladi, J.3
-
20
-
-
80053019743
-
Primary anti-VEGF-refractory metastatic renal cell carcinoma (mRCC): Clinical characteristics, risk factors, and subsequent therapy
-
Abstract 305
-
D.Y. Heng, M.J. MacKenzie, and U.N. Vaishampayan Primary anti-VEGF-refractory metastatic renal cell carcinoma (mRCC): clinical characteristics, risk factors, and subsequent therapy Genitourinary Cancers Symposium 2011 Abstract 305
-
(2011)
Genitourinary Cancers Symposium
-
-
Heng, D.Y.1
MacKenzie, M.J.2
Vaishampayan, U.N.3
-
21
-
-
84857505609
-
-
Accessed: March 24, 2010
-
FDA Approval Letter for Sorafenib http://www.accessdata.fda.gov/ drugsatfda-docs/appletter/2005/021923ltr.pdf Accessed: March 24, 2010
-
FDA Approval Letter for Sorafenib
-
-
-
22
-
-
84857504725
-
-
Accessed: March 24, 2010
-
FDA Approval Letter for Sunitinib http://www.accessdata.fda.gov/ drugsatfda-docs/appletter/2006/021968s000ltr.pdf Accessed: March 24, 2010
-
FDA Approval Letter for Sunitinib
-
-
-
24
-
-
84867317521
-
-
Accessed: June 1, 2011
-
FDA News Release: Temsirolimus http://www.fda.gov/AboutFDA/ CentersOffices/CDER/ucm129247.htm Accessed: June 1, 2011
-
FDA News Release: Temsirolimus
-
-
-
25
-
-
84867317521
-
-
Accessed: June 1, 2011
-
FDA News Release: Pazopanib http://www.fda.gov/AboutFDA/CentersOffices/ CDER/ucm187509.htm Accessed: June 1, 2011
-
FDA News Release: Pazopanib
-
-
-
26
-
-
84857506026
-
-
Accessed: June 1, 2011
-
Afinitor [prescribing information] http://www.accessdata.fda.gov/ drugsatfda-docs/label/2010/022334s6lbl.pdf Accessed: June 1, 2011
-
Afinitor [Prescribing Information]
-
-
|