Amphitrite ornata dehaloperoxidase (DHP): Investigations of structural factors that influence the mechanism of halophenol dehalogenation using "peroxidase-like" myoglobin mutants and "myoglobin-like" DHP mutants

Biochemistry

Volumn 50, Issue 38, 2011, Pages 8172-8180

  Du, Jing ^a   Huang, Xiao ^a   Sun, Shengfang ^a   Wang, Chunxue ^a   Lebioda, Lukasz ^a   Dawson, John H ^a,b  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLOGRAPHIC DATA; DISTAL HISTIDINE; DOUBLE MUTANTS; DUAL-FUNCTION ENZYMES; HALOPHENOLS; HEME IRON; IMIDAZOLATE; LIGAND-FREE; LIVING ENVIRONMENT; MECHANISM OF ACTION; MOLECULAR EVOLUTION; NEGATIVE CHARGE; OXYGEN CARRIER; PEROXIDASE ACTIVITIES; SPERM WHALES; STRUCTURAL FACTOR; WILD TYPES; WILD-TYPE PROTEINS;

AMINO ACIDS; CATALYST ACTIVITY; HEMOGLOBIN; MOLECULAR BIOLOGY; PORPHYRINS; X RAY CRYSTALLOGRAPHY;

CRYSTAL STRUCTURE;

DEHALOPEROXIDASE; HALOPHENOL; MYOGLOBIN; PEROXIDASE; UNCLASSIFIED DRUG;

AMPHITRITE ORNATA; ARTICLE; DEHALOGENATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; LIGHT ABSORPTION; NONHUMAN; POLYCHAETA; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; ANIMALS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; EVOLUTION, MOLECULAR; HEMOGLOBINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; MYOGLOBIN; PEROXIDASES; POLYCHAETA; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY;

AMPHITRITE ORNATA; PHYSETERIDAE; POLYCHAETA; TEREBELLIDA;

EID: 80053039198     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2009129     Document Type: Article

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