Characterization of the biosynthesis, processing and kinetic mechanism of action of the enzyme deficient in mucopolysaccharidosis IIIC

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Fan, Xiaolian ^a   Tkachyova, Ilona ^a,b   Sinha, Ankit ^a   Rigat, Brigitte ^a   Mahuran, Don ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; LIPID; DETERGENT; HGSNAT PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; HELA CELL; HUMAN; HUMAN CELL; LYSOSOME; MUCOPOLYSACCHARIDOSIS; PATHOPHYSIOLOGY; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROCESSING; SANFILIPPO SYNDROME TYPE C; SKIN FIBROBLAST; CHEMICAL PHENOMENA; CHEMISTRY; ENDOPLASMIC RETICULUM; ENZYME ASSAY; ENZYMOLOGY; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; PROTEIN TRANSPORT; SANFILIPPO SYNDROME; TEMPERATURE; WESTERN BLOTTING;

ACETYLTRANSFERASES; BLOTTING, WESTERN; DETERGENTS; ENDOPLASMIC RETICULUM; ENZYME ASSAYS; HELA CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; MUCOPOLYSACCHARIDOSIS III; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; TEMPERATURE;

EID: 80053037444     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024951     Document Type: Article

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