Pain and its control

Current Medical Research and Opinion

Volumn 27, Issue 10, 2011, Pages 2075-2078

  Dickenson, Anthony ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

opioid receptor; Analgesic action; Central sensitisation; Multiple pain mechanisms; Neuropathic pain; Nociceptive pain; Signalling

Indexed keywords

BENZOCAINE; CALCIUM CHANNEL; CARBAMAZEPINE; LIDOCAINE; MU OPIATE RECEPTOR AGONIST; NEUROTRANSMITTER; NONSTEROID ANTIINFLAMMATORY AGENT; NORADRENALIN; NORADRENALIN UPTAKE INHIBITOR; POTASSIUM CHANNEL; PROSTAGLANDIN SYNTHASE; SEROTONIN; SEROTONIN UPTAKE INHIBITOR;

ARTHRITIS; CANCER PAIN; CONFERENCE PAPER; DIABETES MELLITUS; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; INFLAMMATION; LOW BACK PAIN; NERVE BLOCK; NEUROPATHIC PAIN; NEUROTRANSMITTER RELEASE; NOCICEPTIVE RECEPTOR; PAIN; PAIN THRESHOLD; POSTHERPETIC NEURALGIA; SIGNAL TRANSDUCTION;

CONGRESSES AS TOPIC; FEMALE; HUMANS; MALE; NOCICEPTIVE PAIN; PAIN MANAGEMENT;

EID: 80053023484     PISSN: 03007995     EISSN: 14734877     Source Type: Journal    
DOI: 10.1185/03007995.2011.619445     Document Type: Conference Paper

References (20)

1. Woolf CJ. Pain: moving from symptom control toward mechanism-specific pharmacologic management. Ann Intern Med 2004;140:441-51 (Pubitemid 38327332)
2. Costigan M, Scholz J, Woolf CJ. Neuropathic pain: a maladaptive response of the nervous system to damage. Annu Rev Neurosci 2009;32:1-32
3. Markenson JA. Mechanisms of chronic pain. Am J Med 1996;101:6S-18S (Pubitemid 26269071)
4. Botting RM, Botting JH. Pathogenesis and mechanisms of inflammation and pain: an overview. Clin Drug Invest 2000;19(Suppl 2):1-7 (Pubitemid 30348977)
5. Wang S-Y, Mitchell J, Moczydlowski E, et al. Block of inactivation-deficient Na\+ channels by local anesthetics in stably transfected mammalian cells. J Gen Physiol 2004;124:691-701
6. Geber C, Baumgä rtner U, Schwab R, et al. Revised definition of neuropathic pain and its grading system: an open case series illustrating its use in clinical practice. Am J Med 2009;122:S3-S12
7. Hargus NJ, Patel MK. Voltage-gated Na\+ channels in neuropathic pain. Expert Opin Investig Drugs 2007;16:635-46
8. Munro G, Dalby-Brown W. Kv7 (KCNQ) channel modulators and neuropathic pain. J Med Chem 2007;50:2576-82 (Pubitemid 46896062)
9. Todorovic SM, Jevtovic-Todorovic V. The role of T-type calcium channels in peripheral and central pain processing. CNS Neurol Disord Drug Targets 2006;5:639-53 (Pubitemid 44890575)
10. Mantegazza M, Catterall WA. Voltage-gated Na\+ channels and epilepsy. Lancet Neurol 2010;9:13-24
11. Kalso E. Sodium channel blockers in neuropathic pain. Curr Pharm Des 2005;11:3005-11 (Pubitemid 41149937)
12. Tzellos TG, Papazisis G, Toulis KA. A2delta ligands gabapentin and pregabalin: future implications in daily clinical practice. Hippokratia 2010;14:71-5
13. Woolf CJ. Pain. Central sensitization: implications for the diagnosis and treatment of pain 2011;152(Suppl 3):S2-S15
14. Nicholson B, Verma S. Comorbidities in chronic neuropathic pain. Pain Med 2004;5(Suppl 1):S9-S27 (Pubitemid 38404454)
15. Przewłocki R, Przewłocka B. Opioids in chronic pain. Eur J Pharmacol 2001;429:79-91 (Pubitemid 33043984)
16. Kohno T, Kumamoto E, Higashi H, et al. Actions of opioids on excitatory and inhibitory transmission in substantia gelatinosa of adult rat spinal cord. J Physiol 1999;518:803-13 (Pubitemid 29387249)
17. Zieglgä nsberger W, Bayerl H. The mechanism of inhibition of neuronal activity by opiates in the spinal cord of cat. Brain Res 1976;115:111-28
18. Heinricher MM, Tavares I, Leith JL, et al. Descending control of nociception: specificity, recruitment and plasticity. Brain Res Rev 2009;60: 214-25
19. Marks DM, Shah MJ, Patkar AA, et al. Serotonin-norepinephrine reuptake inhibitors for pain control: premise and promise. Curr Neuropharmacol 2009;7:331-6
20. Lynch ME. Antidepressants as analgesics: a review of randomized controlled trials. J Psychiatry Neurosci 2001;26:30-6 (Pubitemid 32185177)