Development an efficient route to the 5-lipoxygenase inhibitor PF-04191834

Organic Process Research and Development

Volumn 15, Issue 5, 2011, Pages 1046-1051

  De Koning, Pieter D ^a   Murtagh, Lorraine ^a   Lawson, Jon P ^a,e,f   Vonder Embse, Richard A ^b   Kunda, Sastry A ^c   Kong, Wei ^d  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^b PFIZER INC   (United States)

^c J P Lawson Consulting LLC   (United States)

^d NOVUS INTERNATIONAL INC   (United States)

^e Covidien ^*  (United States)

^f MEDTRONIC INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOND-FORMING STEP; DISPROPORTIONATIONS; DOWNSTREAM-PROCESSING; MEDICINAL CHEMISTRY; REACTION CONDITIONS; SCALE-UP; SIX-STEP PROCESS; THIOETHER LINKAGES;

PALLADIUM; SYNTHESIS (CHEMICAL);

COLUMN CHROMATOGRAPHY;

EID: 80053009719     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op200173g     Document Type: Article

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