Role of cellular cholesterol metabolism in vascular cell calcification

Journal of Biological Chemistry

Volumn 286, Issue 38, 2011, Pages 33701-33706

  Geng, Yifan ^a   Hsu, Jeffrey J ^a   Lu, Jinxiu ^b   Ting, Tabitha C ^d   Miyazaki, Makoto ^d   Demer, Linda L ^a,b,c   Tintut, Yin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of California   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE ACTIVITY; BIOSYNTHESIS PATHWAYS; CARDIOVASCULAR EVENT; CELL-PERMEABLE; CELLULAR CHOLESTEROL; CHOLESTEROL METABOLISM; FORSKOLIN; HMG-COA REDUCTASE; INTEGRAL COMPONENTS; INTRACELLULAR CHOLESTEROL; LIVER X RECEPTORS; MATRIX MINERALIZATION; MATRIX VESICLES; OSTEOGENIC DIFFERENTIATION; UP-REGULATION; VASCULAR CALCIFICATION; VASCULAR CELLS; VASCULAR SMOOTH MUSCLE CELLS; WT CELLS;

BIOMINERALIZATION; BIOSYNTHESIS; BONE; CHOLESTEROL; CYTOLOGY; ENZYME ACTIVITY; GENES; METABOLISM; MINERALOGY; MUSCLE; PHOSPHATASES; PHYSIOLOGY;

CELLS;

ALKALINE PHOSPHATASE; CHOLESTEROL; COMPACTIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LOW DENSITY LIPOPROTEIN RECEPTOR;

ANIMAL CELL; ARTICLE; BIOMINERALIZATION; BLOOD VESSEL CALCIFICATION; CELL DIFFERENTIATION; CELL LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE INDUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE; WILD TYPE;

ANIMALS; BLOOD VESSELS; BONE MATRIX; CALCIFICATION, PHYSIOLOGIC; CALCINOSIS; CATTLE; CELL DIFFERENTIATION; CHOLESTEROL; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; MICE; MYOCYTES, SMOOTH MUSCLE; OSTEOBLASTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERUM;

MUS;

EID: 80053008382     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.269639     Document Type: Article

References (28)

1. Johnson, R. C., Leopold, J. A., and Loscalzo, J. (2006) Circ. Res. 99, 1044-1059
2. Jono, S., Shioi, A., Ikari, Y., and Nishizawa, Y. (2006) J. Bone Miner. Metab. 24, 176-181
3. Mizobuchi, M., Towler, D., and Slatopolsky, E. (2009) J. Am. Soc. Nephrol. 20, 1453-1464
4. Sage, A. P., Tintut, Y., and Demer, L. L. (2010) Nat. Rev. Cardiol. 7, 528-536
5. Abedin, M., Tintut, Y., and Demer, L. L. (2004) Arterioscler. Thromb. Vasc. Biol. 24, 1161-1170
6. Giachelli, C. M. (2009) Kidney Int. 75, 890-897
7. Hsu, J. J., Tintut, Y., and Demer, L. L. (2008) Curr. Drug Targets 9, 224-228
8. Neven, E., and D'Haese, P. C. (2011) Circ. Res. 108, 249-264
9. Neves, K. R., Graciolli, F. G., dos Reis, L. M., Graciolli, R. G., Neves, C. L., Magalhães, A. O., Custódio, M. R., Batista, D. G., Jorgetti, V., and Moysés, R. M. (2007) Kidney Int. 71, 1262-1270
10. Rattazzi, M., Bennett, B. J., Bea, F., Kirk, E. A., Ricks, J. L., Speer, M., Schwartz, S. M., Giachelli, C. M., and Rosenfeld, M. E. (2005) Arterioscler. Thromb. Vasc. Biol. 25, 1420-1425
11. Huang, M. S., Sage, A. P., Lu, J., Demer, L. L., and Tintut, Y. (2008) Biochem. Biophys. Res. Commun. 374, 553-558
12. Tintut, Y., Patel, J., Parhami, F., and Demer, L. L. (2000) Circulation 102, 2636-2642
13. Siddappa, R., Martens, A., Doorn, J., Leusink, A., Olivo, C., Licht, R., van Rijn, L., Gaspar, C., Fodde, R., Janssen, F., van Blitterswijk, C., and de Boer, J. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 7281-7286
14. Peress, N. S., Anderson, H. C., and Sajdera, S. W. (1974) Calcif. Tissue Res. 14, 275-281
15. Chen, N. X., O'Neill, K. D., Chen, X., and Moe, S. M. (2008) J. Bone Miner. Res. 23, 1798-1805
16. Reynolds, J. L., Joannides, A. J., Skepper, J. N., McNair, R., Schurgers, L. J., Proudfoot, D., Jahnen-Dechent, W., Weissberg, P. L., and Shanahan, C. M. (2004) J. Am. Soc. Nephrol. 15, 2857-2867
17. Sawada, N., Taketani, Y., Amizuka, N., Ichikawa, M., Ogawa, C., Nomoto, K., Nashiki, K., Sato, T., Arai, H., Isshiki, M., Segawa, H., Yamamoto, H., Miyamoto, K., and Takeda, E. (2007) Bone 41, 52-58
18. Brown, M. S., and Goldstein, J. L. (1984) Sci. Am. 251, 58-66
19. Yamamoto, T., Davis, C. G., Brown, M. S., Schneider, W. J., Casey, M. L., Goldstein, J. L., and Russell, D. W. (1984) Cell 39, 27-38
20. Tintut, Y., Parhami, F., Boström, K., Jackson, S. M., and Demer, L. L. (1998) J. Biol. Chem. 273, 7547-7553
21. Ting, T. C., Miyazaki-Anzai, S., Masuda, M., Levi, M., Demer, L. L., Tintut, Y., and Miyazaki, M. (2011) J. Biol. Chem. 286, 23938-239449
22. Sage, A. P., Lu, J., Tintut, Y., and Demer, L. L. (2011) Kidney Int. 79, 414-422
23. Joseph, S. B., McKilligin, E., Pei, L., Watson, M. A., Collins, A. R., Laffitte, B. A., Chen, M., Noh, G., Goodman, J., Hagger, G. N., Tran, J., Tippin, T. K., Wang, X., Lusis, A. J., Hsueh, W. A., Law, R. E., Collins, J. L., Willson, T. M., and Tontonoz, P. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 7604-7609
24. Terasaka, N., Hiroshima, A., Koieyama, T., Ubukata, N., Morikawa, Y., Nakai, D., and Inaba, T. (2003) FEBS Lett. 536, 6-11
25. Hsu, J. J., Lu, J., Huang, M. S., Geng, Y., Sage, A. P., Bradley, M. N., Tontonoz, P., Demer, L. L., and Tintut, Y. (2009) FEBS Lett. 583, 1344-1348
26. Yokoyama, C., Wang, X., Briggs, M. R., Admon, A., Wu, J., Hua, X., Goldstein, J. L., and Brown, M. S. (1993) Cell 75, 187-197
27. Kizu, A., Shioi, A., Jono, S., Koyama, H., Okuno, Y., and Nishizawa, Y. (2004) J. Cell. Biochem. 93, 1011-1019
28. Jain, M. K., and Ridker, P. M. (2005) Nat. Rev. Drug Discov. 4, 977-987