Hypoxia signature of splice forms of tryptophanyl-tRNA synthetase marks pancreatic cancer cells with distinct metastatic abilities

Pancreas

Volumn 40, Issue 7, 2011, Pages 1043-1056

  Paley, Elena L ^a,b   Paley, Deana E ^c   Merkulova Rainon, Tatyana ^d   Subbarayan, Pochi R ^e  

^a NOVA SOUTHEASTERN UNIVERSITY   (United States)

^b Expert BioMed Inc   (United States)

^c ST BARNABAS HOSPITAL   (United States)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

antiangiogenic factor; cyclin B1 positive asymmetric mitosis; HIF 1 ; hypoxic pancreatic cancer stem cells; spheroids; tryptophanyl tRNA synthetase

Indexed keywords

CYCLIN B1; EPITOPE; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; MONOCLONAL ANTIBODY; TRYPTOPHAN TRANSFER RNA LIGASE;

ARTICLE; CANCER CELL CULTURE; DOWN REGULATION; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; METASTASIS; PANCREAS CANCER; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPHEROID CELL; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL HYPOXIA; CYCLIN B1; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCOSE TRANSPORTER TYPE 1; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; NEOPLASM INVASIVENESS; OXYGEN; PANCREATIC NEOPLASMS; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPHEROIDS, CELLULAR; TIME FACTORS; TRYPTOPHAN-TRNA LIGASE; TUMOR MARKERS, BIOLOGICAL;

EID: 80052972546     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0b013e318222e635     Document Type: Article

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