Prognostic implications of lymph node metastases in carcinoma of the body and tail of the pancreas

Pancreas

Volumn 40, Issue 7, 2011, Pages 1029-1033

  Sahin, Tevfik T ^a   Fujii, Tsutomu ^a   Kanda, Mitsuro ^a   Nagai, Shunji ^a   Kodera, Yasuhiro ^a   Kanzaki, Akiyuki ^a   Yamamura, Kazuo ^a   Sugimoto, Hiroyuki ^a   Kasuya, Hideki ^a   Nomoto, Shuji ^a   Takeda, Shin ^a   Morita, Satoshi ^b   Nakao, Akimasa ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

distal pancreatectomy; left sided pancreatic cancer; lymph node metastasis; metastatic lymph node ratio

Indexed keywords

ADULT; AGED; ARTICLE; CANCER STAGING; CANCER SURVIVAL; FEMALE; HISTOPATHOLOGY; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PANCREAS ADENOCARCINOMA; PANCREAS RESECTION; PRIORITY JOURNAL; PROGNOSIS;

ADENOCARCINOMA; ADULT; AGED; CHI-SQUARE DISTRIBUTION; FEMALE; HUMANS; JAPAN; KAPLAN-MEIER ESTIMATE; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; PANCREATECTOMY; PANCREATIC NEOPLASMS; PROPORTIONAL HAZARDS MODELS; RISK ASSESSMENT; RISK FACTORS; SURVIVAL RATE; TIME FACTORS; TREATMENT OUTCOME;

EID: 80052967341     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0b013e3182207893     Document Type: Article

References (30)

1. Kanda M, Fujii T, Kodera Y, et al. Nutritional predictors of postoperative outcome in pancreatic cancer. Br J Surg. 2011;98:268-274.
2. Nakao A, Harada A, Nonami T, et al. Lymph node metastasis in carcinoma of the body and tail of the pancreas. Br J Surg. 1997;84:1090-1092. (Pubitemid 27359480)
3. Murakami Y, Uemura K, Sudo T, et al. Impact of adjuvant gemcitabine plus S-1 chemotherapy after surgical resection for adenocarcinoma of the body or tail of the pancreas. J Gastrointest Surg. 2009;13:85-92.
4. Shimada K, Sakamoto Y, Sano T, et al. Prognostic factors after distal pancreatectomy with extended lymphadenectomy for invasive pancreatic adenocarcinoma of the body and tail. Surgery. 2006;139:288-295.
5. Kayahara M, Nagakawa T, Futagami F, et al. Lymphatic flow and neural plexus invasion associated with carcinoma of the body and tail of the pancreas. Cancer. 1996;78:2485-2491. (Pubitemid 26415679)
6. Verbeke CS, Leitch D, Menon KV, et al. Redefining the R1 resection in pancreatic cancer. Br J Surg. 2006;93:1232-1237. (Pubitemid 44547022)
7. Artinyan A, Soriano PA, Prendergast C, et al. The anatomic location of pancreatic cancer is a prognostic factor for survival. HPB (Oxford). 2008;10:371-376.
8. Howard TJ, Krug JE, Yu J, et al. A margin-negative R0 resection accomplished with minimal postoperative complications is the surgeon's contribution to long-term survival in pancreatic cancer. J Gastrointest Surg. 2006;10:1338-1345.
9. Ueda M, Endo I, Nakashima M, et al. Prognostic factors after resection of pancreatic cancer. World J Surg. 2009;33:104-110.
10. Ozaki H, Kinoshita T, Kosuge T, et al. An aggressive therapeutic approach to carcinoma of the body and tail of the pancreas. Cancer. 1996;77:2240-2245. (Pubitemid 26162415)
11. Shoup M, Conlon KC, Klimstra D, et al. Is extended resection for adenocarcinoma of the body or tail of the pancreas justified? J Gastrointest Surg. 2003;7:946-952. (Pubitemid 37524061)
12. Fujita T, Nakagohri T, Gotohda N, et al. Evaluation of the prognostic factors and significance of lymph node status in invasive ductal carcinoma of the body or tail of the pancreas. Pancreas. 2010; 39:48-54.
13. Murakami Y, Uemura K, Sudo T, et al. Prognostic impact of para-aortic lymph node metastasis in pancreatic ductal adenocarcinoma. World J Surg. 2010;34:1900-1907.
14. Murakami Y, Uemura K, Sudo T, et al. Number of metastatic lymph nodes, but not lymph node ratio, is an independent prognostic factor after resection of pancreatic carcinoma. J Am Coll Surg. 2010;211:196-204.
15. Japan Pancreas Society. Classification of Pancreatic Carcinoma. Second English edition. Tokyo: Kanehara & Co; 2003.
16. International Union Against Cancer. TNM Classification of Malignant Tumors. Seventh edition. New York: Wiley-Blackwell; 2009.
17. Tamandl D, Kaczirek K, Gruenberger B, et al. Lymph node ratio after curative surgery for intrahepatic cholangiocarcinoma. Br J Surg. 2009;96:919-925.
18. Kim YS, Kim JH, Yoon SM, et al. Lymph node ratio as a prognostic factor in patients with stage III rectal cancer treated with total mesorectal excision followed by chemoradiotherapy. Int J Radiat Oncol Biol Phys. 2009;74:796-802.
19. Huang CM, Lin BJ, Lu HS, et al. Prognostic impact of metastatic lymph node ratio in advanced gastric cancer from cardia and fundus. World J Gastroenterol. 2008;14:4383-4388.
20. Lee HY, Choi HJ, Park KJ, et al. Prognostic significance of metastatic lymph node ratio in node-positive colon carcinoma. Ann Surg Oncol. 2007;14:1712-1717.
21. Bogoevski D, Onken F, Koenig A, et al. Is it time for a new TNM classification in esophageal carcinoma? Ann Surg. 2008; 247:633-641. (Pubitemid 351440614)
22. Peschaud F, Benoist S, Julie C, et al. The ratio of metastatic to examined lymph nodes is a powerful independent prognostic factor in rectal cancer. Ann Surg. 2008;248:1067-1073.
23. Kulig J, Sierzega M, Kolodziejczyk P, et al. Polish Gastric Cancer Study Group. Ratio of metastatic to resected lymph nodes for prediction of survival in patients with inadequately staged gastric cancer. Br J Surg. 2009;96:910-918.
24. Pawlik TM, Gleisner AL, Cameron JL, et al. Prognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancer. Surgery. 2007;141:610-618. (Pubitemid 46616937)
25. Sakai M, Nakao A, Kaneko T, et al. Para-aortic lymph node metastasis in carcinoma of the head of the pancreas. Surgery. 2005; 137:606-611. (Pubitemid 40755416)
26. Nakao A, Nonami T, Harada A, et al. Portal vein resection with a new antithrombogenic catheter. Surgery. 1990;108:913-918. (Pubitemid 20385316)
27. Delcore R, Rodriguez FJ, Forster J, et al. Significance of lymph node metastases in patients with pancreatic cancer undergoing curative resection. Am J Surg. 1996;172:463-468.
28. Cubilla AL, Fortner J, Fitzgerald PJ. Lymph node involvement in carcinoma of the head of the pancreas area. Cancer. 1978; 41:880-887. (Pubitemid 8313223)
29. Fernández-Cruz L, Johnson C, Dervenis C. Locoregional dissemination and extended lymphadenectomy in pancreatic cancer. Dig Surg. 1999;16:313-319. (Pubitemid 29376333)
30. Han SL, Zhang WJ, Zheng XF, et al. Radical resection and outcome for malignant tumors of the pancreatic body and tail. World J Gastroenterol. 2009;15:5346-5351.