Ratio of metastatic to resected lymph nodes for prediction of survival in patients with inadequately staged gastric cancer

British Journal of Surgery

Volumn 96, Issue 8, 2009, Pages 910-918

  Kulig, J ^a   Sierzega, M ^a   Kolodziejczyk, P ^a   Popiela, T ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE; ARTICLE; CANCER INVASION; CANCER STAGING; CANCER SURVIVAL; FEMALE; GASTRECTOMY; HUMAN; LYMPH NODE METASTASIS; LYMPHADENECTOMY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; STOMACH CANCER; TUMOR LOCALIZATION;

ADULT; AGED; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; STOMACH NEOPLASMS; SURVIVAL ANALYSIS;

EID: 68049102207     PISSN: 00071323     EISSN: 13652168     Source Type: Journal    
DOI: 10.1002/bjs.6653     Document Type: Article

References (33)

1. Bouvier AM, Haas O, Piard F, Roignot P, Bonithon-Kopp C, Faivre J. How many nodes must be examined to accurately stage gastric carcinomas? Results from a population based study. Cancer 2002; 94: 2862-2866.
2. Greene FL, Compton CC, Fritz AG, Shah JP, Winchester DP. AJCC Cancer Staging Atlas. Springer: Berlin, 2006.
3. Wagner PK, Ramaswamy A, Rüschoff J, Schmitz-Moormann P, Rothmund M. Lymph node counts in the upper abdomen: anatomical basis for lymphadenectomy in gastric cancer. Br J Surg 1991; 78: 825-827.
4. Bunt AM, Hermans J, Smit VT, van de Velde CJ, Fleuren GJ, Bruijn JA. Surgical/pathologic-stage migration confounds comparisons of gastric cancer survival rates between Japan and Western countries. J Clin Oncol 1995; 13: 19-25.
5. Noguchi Y, Imada T, Matsumoto A, Coit DG, Brennan MF. Radical surgery for gastric-cancer - a review of the Japanese experience. Cancer 1989; 64: 2053-2062.
6. Yu W, Choi GS, Whang I, Suh IS. Comparison of five systems for staging lymph node metastasis in gastric cancer. Br J Surg 1997; 84: 1305-1309.
7. Mullaney PJ, Wadley MS, Hyde C,Wyatt J, Lawrence G, Hallissey MT et al. Appraisal of compliance with the UICC/AJCC staging system in the staging of gastric cancer. Union Internacional Contra la Cancrum/American Joint Committee on Cancer. Br J Surg 2002; 89: 1405-1408.
8. Hundahl SA, Phillips JL, Menck HR. The National Cancer Data Base Report on poor survival of U.S. gastric carcinoma patients treated with gastrectomy: Fifth Edition American Joint Committee on Cancer staging, proximal disease, and the 'different disease' hypothesis. Cancer 2000; 88: 921-932.
9. Baxter NN, Tuttle TM. Inadequacy of lymph node staging in gastric cancer patients: a population-based study. Ann Surg Oncol 2005; 12: 981-987.
10. Hundahl SA, Macdonald JS, Benedetti J, Fitzsimmons T, Southwest Oncology Group and the Gastric Intergroup. Surgical treatment variation in a prospective, randomized trial of chemoradiotherapy in gastric cancer: the effect of undertreatment. Ann Surg Oncol 2002; 9: 278-286.
11. Bando E, Yonemura Y, Taniguchi K, Fushida S, Fujimura T, Miwa K. Outcome of ratio of lymph node metastasis in gastric carcinoma. Ann Surg Oncol 2002; 9: 775-784.
12. HyungWJ, Noh SH, Yoo CH, Huh JH, Shin DW, Lah KH et al. Prognostic significance of metastatic lymph node ratio in T3 gastric cancer. World J Surg 2002; 26: 323-329.
13. Inoue K, Nakane Y, Iiyama H, Sato M, Kanbara T, Nakai K et al. The superiority of ratio-based lymph node staging in gastric carcinoma. Ann Surg Oncol 2002; 9: 27-34.
14. Kim J-P, Lee JH, Kim SJ, Yu HJ, Yang HK. Clinicopathologic characteristics and prognostic factors in 10 783 patients with gastric cancer. Gastric Cancer 1998; 1: 125-133.
15. Kodera Y, Yamamura Y, Shimizu Y, Torii A, Hirai T, Yasui K et al. Metastatic gastric lymph node rate is a significant prognostic factor for resectable stage IV stomach cancer. J Am Coll Surg 1997; 185: 65-69.
16. Kodera Y, Yamamura Y, Shimizu Y, Torii A, Hirai T, Yasui K et al. Lymph node status assessment for gastric carcinoma: is the number of metastatic lymph nodes really practical as a parameter for N categories in the TNM Classification? Tumor Node Metastasis. J Surg Oncol 1998; 69: 15-20.
17. Kwon SJ, Kim GS. Prognostic significance of lymph node metastasis in advanced carcinoma of the stomach. Br J Surg 1996; 83: 1600-1603.
18. Nitti D, Marchet A, Olivieri M, Ambrosi A, Mencarelli R, Belluco C et al. Ratio between metastatic and examined lymph nodes is an independent prognostic factor after D2 resection for gastric cancer: analysis of a large European monoinstitutional experience. Ann Surg Oncol 2003; 10: 1077-1085.
19. Rodríguez Santiago JM, Muñoz E, Martí M, Quintana S, Veloso E, Marco C. Metastatic lymph node ratio as a prognostic factor in gastric cancer. Eur J Surg Oncol 2005; 31: 59-66.
20. Costa ML, de Cássia Braga Ribeiro K, Machado MA, Costa AC, Montagnini AL. Prognostic score in gastric cancer: the importance of a conjoint analysis of clinical, pathologic, and therapeutic factors. Ann Surg Oncol 2006; 13: 843-850.
21. McKee MD, Posner MC. The staging of gastric cancer: nothing novel but perhaps better. Ann Surg Oncol 2003; 10: 1005-1006.
22. Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma - 2nd English edition. Gastric Cancer 1998; 1: 10-24.
23. Slinker BK, Glantz SA. Multiple regression for physiological data analysis: the problem of multicollinearity. Am J Physiol 1985; 249: R1-R12.
24. Liu RX, Kuang J, Gong Q, Hou XL. Principal component regression analysis with SPSS. Comput Methods Programs Biomed 2003; 71: 141-147.
25. Katai H, Yoshimura K, Maruyama K, Sasako M, Sano T. Evaluation of the new International Union Against Cancer TNM staging for gastric carcinoma. Cancer 2000; 88: 1796-1800.
26. Lee HK, YangHK, KimWH, Lee KU, Choe KJ, KimJP. Influence of the number of lymph nodes examined on staging of gastric cancer. Br J Surg 2001; 88: 1408-1412.
27. Wu CW, Hsieh MC, Lo SS, Tsay SH, Lui WY, P'Eng FK. Relation of number of positive lymph nodes to the prognosis of patients with primary gastric adenocarcinoma. Gut 1996; 38: 525-527.
28. Karpeh MS, Leon L, Klimstra D, Brennan MF. Lymph node staging in gastric cancer: is location more important than number? An analysis of 1038 patients. Ann Surg 2000; 232: 362-371.
29. Bunt AM, Hermans J, van de Velde CJ, Sasako M, Hoefsloot FA, Fleuren G et al. Lymph node retrieval in a randomized trial on western-type versus Japanese-type surgery in gastric cancer. J Clin Oncol 1996; 14: 2289-2294.
30. Siewert JR, Böttcher K, Roder JD, Busch R, Hermanek P, Meyer HJ. Prognostic relevance of systematic lymph node dissection in gastric carcinoma. German Gastric Carcinoma Study Group. Br J Surg 1993; 80: 1015-1018.
31. Smith DD, Schwarz RR, Schwarz RE. Impact of total lymph node count on staging and survival after gastrectomy for gastric cancer: data from a large US-population database. J Clin Oncol 2005; 23: 7114-7124.
32. Siewert JR, Böttcher K, Stein HJ, Roder JD. Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study. Ann Surg 1998; 228: 449-461.
33. Marchet A, Mocellin S, Ambrosi A, Morgagni P, Garcea D, Marrelli D et al. The ratio between metastatic and examined lymph nodes (N ratio) is an independent prognostic factor in gastric cancer regardless of the type of lymphadenectomy: results from an Italian multicentric study in 1853 patients. Ann Surg 2007; 245: 543-552.