Resistant trichomoniasis: Successful treatment with combination therapy

Sexually Transmitted Diseases

Volumn 38, Issue 10, 2011, Pages 962-963

  Nyirjesy, Paul ^a   Gilbert, Jeffrey ^b   Mulcahy, Laura J ^b  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b MONTEFIORE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL VIOLET; FURAZOLIDONE; LIDOCAINE; METRONIDAZOLE; MICONAZOLE; NITAZOXANIDE; NONOXINOL 9; PAROMOMYCIN; PERMANGANATE POTASSIUM; POVIDONE IODINE; TINIDAZOLE;

ADULT; ARTICLE; CASE REPORT; DRUG EFFICACY; DRUG INDICATION; DRUG MEGADOSE; DRUG TOLERABILITY; DRUG TREATMENT FAILURE; FEMALE; HUMAN; NONHUMAN; SKIN IRRITATION; TREATMENT DURATION; TREATMENT RESPONSE; TRICHOMONIASIS;

ADMINISTRATION, INTRAVAGINAL; ADMINISTRATION, ORAL; ADULT; ANTIPROTOZOAL AGENTS; ANTITRICHOMONAL AGENTS; COMBINED MODALITY THERAPY; DRUG RESISTANCE, MULTIPLE; FEMALE; HUMANS; MALE; METRONIDAZOLE; MIDDLE AGED; PAROMOMYCIN; SEXUAL PARTNERS; TINIDAZOLE; TREATMENT OUTCOME; TRICHOMONAS VAGINALIS; TRICHOMONAS VAGINITIS;

EID: 80052966499     PISSN: 01485717     EISSN: 15374521     Source Type: Journal    
DOI: 10.1097/OLQ.0b013e31822037e4     Document Type: Article

References (15)

1. Centers for Disease Control and Prevention. Sexually transmitted disease treatment guidelines, 2010. MMWR Recomm Rep 2010; 59:1-110.
2. Sobel JD. What's new in bacterial vaginosis and trichomonas? Infect Dis Clin North Am 2005; 19:387-406. (Pubitemid 40814421)
3. Nyirjesy P, Sobel JD, Weitz MV, et al. Difficult-to-treat trichomoniasis: Results with paromomycin cream. Clin Infect Dis 1998; 26:986-988. (Pubitemid 28180342)
4. Narcisi EM, Secor WE. In vitro effect of tinidazole and furazolidone on metronidazole-resistant Trichomonas vaginalis. Antimicrob Agents Chemother 1996; 40:1121-1125. (Pubitemid 26141395)
5. Sobel JD, Nyirjesy P, Brown W. Tinidazole therapy for metronidazole-resistant vaginal trichomoniasis. Clin Infect Dis 2001; 33:1341-1346. (Pubitemid 32955184)
6. Wong CA, Wilson PD, Chew TA. Povidone-iodine in the treatment of metronidazole resistant Trichomonas vaginalis. Aust N Z J Obstet Gynaecol 1990; 30:169-171. (Pubitemid 20180238)
7. Watson PG, Pattman RS. Arsenical pessaries in the successful elimination of metronidazole-resistant Trichomonas vaginalis. Int J STD AIDS 1996; 7:296-297. (Pubitemid 26284150)
8. Livengood CH, Lossick JG. Resolution of resistant trichomoniasis associated with the use of intravaginal nonoxynol-9. Obstet Gynecol 1991; 78:954-956.
9. Schnell JD. The incidence of vaginal candida and trichomonas infections and treatment of Trichomonas vaginitis with clotrimazole. Postgrad Med J 1974; 50(suppl 1):79-81.
10. Legal HP. The treatment of trichomonas and candidal vaginintis with the use of clotrimazole vaginal tablets. Postgrad Med J 1974; 50(suppl 1):81-83.
11. Nyirjesy P, Weitz MV, Gelone SP, et al. Paromomycin for nitroimidazole-resistant trichomonas. Lancet 1995; 346:1110.
12. Goldman LM, Upcroft JA, Workowski K, et al. Treatment of metrondiazole-resistant Trichomonas vaginalis. Sex Health 2009; 6:345-347.
13. Houang ET, Ahmet Z, Lawrence AG. Successful treatment of four patients with recalcitrant vaginal trichomoniasis with a combination of zinc sulfate douche and metronidazole therapy. Sex Transm Dis 1997; 24:116-119. (Pubitemid 27074480)
14. Kulda J. Trichomonads, hydrogenosomes and drug resistance. Int J Parasitol 1999; 29:199-212. (Pubitemid 29112921)
15. Davidson RN, den Boer M, Ritmeijer K. Paromomycin. Trans R Soc Trop Med Hyg 2009; 103:653-660.