Effects of the L/N-type calcium channel antagonist cilnidipine on morning blood pressure control and peripheral edema formation

Journal of the American Society of Hypertension

Volumn 5, Issue 5, 2011, Pages 410-416

  Narita, Sumito ^a   Yoshioka, Yasuko ^a   Ide, Atsumi ^a   Kadokami, Toshiaki ^a   Momii, Hidetoshi ^a   Yoshida, Masayoshi ^a   Ando, Shin Ichi ^a  

^a Saiseikai Futsukaichi Hospital   (Japan)

Author keywords

Ambulatory blood pressure monitoring; cilnidipine; leg edema; morning hypertension; sympathetic nerve activity

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CILNIDIPINE;

ADULT; ARTICLE; BLOOD PRESSURE MONITORING; BLOOD PRESSURE REGULATION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG DOSE INCREASE; DRUG EFFECT; DRUG INDUCED HEADACHE; FEMALE; FLUSHING; HEART RATE; HUMAN; HYPERTENSION; LEG EDEMA; MALE; MORNING HYPERTENSION; PHYSICAL EXAMINATION; PRIORITY JOURNAL; SIDE EFFECT; SYSTOLIC BLOOD PRESSURE;

AGED; BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; CALCIUM CHANNEL BLOCKERS; DIHYDROPYRIDINES; EDEMA; FEMALE; HEART RATE; HUMANS; HYPERTENSION; LEG; MALE; MIDDLE AGED; SYMPATHETIC NERVOUS SYSTEM;

EID: 80052966262     PISSN: 19331711     EISSN: 18787436     Source Type: Journal    
DOI: 10.1016/j.jash.2011.03.008     Document Type: Article

References (28)

1. K. Kario Clinician's manual on early morning risk management in hypertension 2004 Science Press London 500-11
2. T.D. Giles Circadian rhythm of blood pressure and the relation to cardiovascular events J Hypertens Suppl 24 2006 S11 S16
3. K. Kario Preceding linkage between a morning surge in blood pressure and small artery remodeling: an indicator of prehypertension? J Hypertens 25 2007 1573 1575 (Pubitemid 47056560)
4. K. Kario Time for focus on morning hypertension: pitfall of current antihypertensive medication Am J Hypertens 18 2005 149 151 (Pubitemid 40332541)
5. T. Ogihara, K. Kikuchi, H. Matsuoka, T. Fujita, J. Higaki, and M. Horiuchi The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2009) Hypertens Res 32 2009 3 107
6. H.K. Kain, A.T. Hinman, and M. Sokolow Arterial blood pressure measurements with a portable recorder in hypertensive patients. I. Variability and correlation with "casual" pressures Circulation 30 1964 882 892
7. G. Parati, S. Omboni, and G. Bilo Why is out-of-office blood pressure measurement needed? home blood pressure measurements will increasingly replace ambulatory blood pressure monitoring in the diagnosis and management of hypertension Hypertension 54 2009 181 187
8. T.G. Pickering, N.H. Miller, G. Ogedegbe, L.R. Krakoff, N.T. Artinian, and D. Goff Call to action on use and reimbursement for home blood pressure monitoring: a joint scientific statement from the American Heart Association, American Society of Hypertension, and Preventive Cardiovascular Nurses Association Hypertension 52 2008 10 29
9. E. O'Brien Ambulatory blood pressure measurement: the case for implementation in primary care Hypertension 51 2008 1435 1441
10. T.G. Pickering, D. Shimbo, and D. Haas Ambulatory blood-pressure monitoring N Engl J Med 354 2006 2368 2374
11. R. Yoshimoto, H. Dohmoto, K. Yamada, and A. Goto Prolonged inhibition of vascular contraction and calcium influx by the novel 1,4-dihydropyridine calcium antagonist cinaldipine (frc-8653) Jpn J Pharmacol 56 1991 225 229
12. S. Fujii, K. Kameyama, M. Hosono, Y. Hayashi, and K. Kitamura Effect of cilnidipine, a novel dihydropyridine Ca++-channel antagonist, on N-type Ca++ channel in rat dorsal root ganglion neurons J Pharmacol Exp Ther 280 1997 1184 1191 (Pubitemid 27166712)
13. H. Uneyama, A. Takahara, H. Dohmoto, R. Yoshimoto, K. Inoue, and N. Akaike Blockade of N-type Ca2+ current by cilnidipine (frc-8653) in acutely dissociated rat sympathetic neurones Br J Pharmacol 122 1997 37 42 (Pubitemid 27376017)
14. H. Uneyama, H. Uchida, R. Yoshimoto, S. Ueno, K. Inoue, and N. Akaike Effects of a novel antihypertensive drug, cilnidipine, on catecholamine secretion from differentiated pc12 cells Hypertension 31 1998 1195 1199 (Pubitemid 28191518)
15. N. Ashizawa, S. Seto, Y. Shibata, and K. Yano Bedtime administration of cilnidipine controls morning hypertension Int Heart J 48 2007 597 603 (Pubitemid 350200183)
16. T. Kushiro, N. Watanabe, A. Takahashi, M. Koike, F. Saito, and Y. Otsuka Different effects of L-type and L+N-type calcium channel blockers on hamster cheek pouch venules J Cardiovasc Pharmacol 44 2004 672 675 (Pubitemid 39587428)
17. G. Leonetti, B. Magnani, A.C. Pessina, A. Rappelli, B. Trimarco, and A. Zanchetti Tolerability of long-term treatment with lercanidipine versus amlodipine and lacidipine in elderly hypertensives Am J Hypertens 15 2002 932 940 (Pubitemid 35217397)
18. K. Sakata, M. Shirotani, H. Yoshida, R. Nawada, K. Obayashi, and K. Togi Effects of amlodipine and cilnidipine on cardiac sympathetic nervous system and neurohormonal status in essential hypertension Hypertension 33 1999 1447 1452 (Pubitemid 29282669)
19. T. Obara, T. Ohkubo, J. Funahashi, M. Kikuya, K. Asayama, and H. Metoki Isolated uncontrolled hypertension at home and in the office among treated hypertensive patients from the J-HOME study J Hypertens 23 2005 1653 1660 (Pubitemid 41233424)
20. R.C. Hermida, D.E. Ayala, A. Mojon, and J.R. Fernandez Influence of circadian time of hypertension treatment of cardiovascular risk: results of the MAPEC study Chronobiol Int 27 2010 1629 1651
21. M.W. Gillman, W.B. Kannel, A. Belanger, and R.B. D'Agostino Influence of heart rate on mortality among persons with hypertension: The Framingham Study Am Heart J 125 1993 1148 1154 (Pubitemid 23117352)
22. C.D. Furberg, B.M. Psaty, and J.V. Meyer Nifedipine dose-related increase in mortality in patients with coronary heart disease Circulation 92 1995 1326 1331
23. B.M. Psaty, S.R. Heckbert, T.D. Koepsell, D.S. Siscovick, T.E. Raghunathan, and N.S. Weiss The risk of myocardial infarction associated with antihypertensive drug therapies JAMA 274 1995 620 625
24. M. Ruzicka, and F.H. Leenen Relevance of 24 h blood pressure profile and sympathetic activity for outcome on short-versus long-acting 1,4-dihydropyridines Am J Hypertens 9 1996 86 94
25. J. Minami, Y. Kawano, Y. Makino, H. Matsuoka, and S. Takishita Effects of cilnidipine, a novel dihydropyridine calcium antagonist, on autonomic function, ambulatory blood pressure and heart rate in patients with essential hypertension Br J Clin Pharmacol 50 2000 615 620 (Pubitemid 32010021)
26. T. Konoshita, Y. Makino, T. Kimura, M. Fujii, S. Wakahara, and K. Arakawa A new-generation N/L-type calcium channel blocker leads to less activation of the renin-angiotensin system compared with conventional L type calcium channel blocker J Hypertens 28 2010 2156 2160
27. S.G. Chrysant Proactive compared with passive adverse event recognition: calcium channel blocker-associated edema J Clin Hypertens (Greenwich) 10 2008 716 722
28. M.R. Weir, C. Rosenberger, and J.C. Fink Pilot study to evaluate a water displacement technique to compare effects of diuretics and ace inhibitors to alleviate lower extremity edema due to dihydropyridine calcium antagonists Am J Hypertens 14 2001 963 968 (Pubitemid 32862599)