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Volumn 24, Issue 10, 2011, Pages 1060-1068

Redefining blood pressure targets in high-risk patients: Lessons from coronary endpoints in recent randomized clinical trials

Author keywords

antihypertensive treatment; blood pressure; blood pressure targets; coronary artery disease; high blood pressure; high cardiovascular risk; hypertension; J curve

Indexed keywords

ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR RISK; CORONARY RISK; HEART INFARCTION; HIGH RISK PATIENT; HUMAN; HYPERTENSION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); STROKE;

EID: 80052964675     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1038/ajh.2011.105     Document Type: Article
Times cited : (13)

References (52)
  • 2
    • 0031769003 scopus 로고    scopus 로고
    • Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension
    • DOI 10.1097/00004872-199816120-00016
    • Liu L, Wang JG, Gong L, Liu G, Staessen JA. Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension. Systolic Hypertension in China (Syst-China) Collaborative Group. J Hypertens 1998; 16:1823-1829. (Pubitemid 28548522)
    • (1998) Journal of Hypertension , vol.16 , Issue.12 , pp. 1823-1829
    • Liu, L.1    Wang, J.G.2    Gong, L.3    Liu, G.4    Staessen, J.A.5
  • 3
    • 0025831464 scopus 로고
    • Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP)
    • SHEP Cooperative Research Group
    • SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 1991; 265:3255-3264.
    • (1991) JAMA , vol.265 , pp. 3255-3264
  • 6
    • 0344373794 scopus 로고    scopus 로고
    • Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)
    • The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group
    • The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002; 288:2981-2997.
    • (2002) JAMA , vol.288 , pp. 2981-2997
  • 7
    • 24644443331 scopus 로고    scopus 로고
    • Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): A multicentre randomised controlled trial
    • DOI 10.1016/S0140-6736(05)67185-1, PII S0140673605671851
    • Dahlöf B, Sever PS, Poulter NR, Wedel H, Beevers DG, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O'Brien E, Ostergren J; ASCOT Investigators. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet 2005; 366:895-906. (Pubitemid 41265663)
    • (2005) Lancet , vol.366 , Issue.9489 , pp. 895-906
    • Dahlof, B.1    Sever, P.S.2    Poulter, N.R.3    Wedel, H.4    Beevers, D.G.5    Caulfield, M.6    Collins, R.7    Kjeldsen, S.E.8    Kristinsson, A.9    McInnes, G.T.10    Mehlsen, J.11    Nieminen, M.12    O'Brien, E.13    Ostergren, J.14
  • 8
    • 2942635317 scopus 로고    scopus 로고
    • Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: The VALUE randomised trial
    • DOI 10.1016/S0140-6736(04)16451-9, PII S0140673604164519
    • Julius S, Kjeldsen SE, Weber M, Brunner HR, Ekman S, Hansson L, Hua T, Laragh J, McInnes GT, Mitchell L, Plat F, Schork A, Smith B, Zanchetti A; VALUE trial group. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004; 363:2022-2031. (Pubitemid 38781102)
    • (2004) Lancet , vol.363 , Issue.9426 , pp. 2022-2031
    • Julius, S.1    Kjeldsen, S.E.2    Weber, M.3    Brunner, H.R.4    Ekman, S.5    Hansson, L.6    Hua, T.7    Laragh, J.8    McInnes, G.T.9    Mitchell, L.10    Plat, F.11    Schork, A.12    Smith, B.13    Zanchetti, A.14
  • 10
    • 53049109468 scopus 로고    scopus 로고
    • Telmisartan randomised assessment study in ACE intolerant subjects with cardiovascular disease (TRANSCEND) investigators effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: A randomised controlled trial
    • Yusuf S, Teo K, Anderson C, Pogue J, Dyal L, Copland I, Schumacher H, Dagenais G, Sleight P; Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) Investigators. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: A randomised controlled trial. Lancet 2008; 372:1174-1183.
    • (2008) Lancet , vol.372 , pp. 1174-1183
    • Yusuf, S.1    Teo, K.2    Anderson, C.3    Pogue, J.4    Dyal, L.5    Copland, I.6    Schumacher, H.7    Dagenais, G.8    Sleight, P.9
  • 12
    • 0042330455 scopus 로고    scopus 로고
    • Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: Randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study)
    • DOI 10.1016/S0140-6736(03)14286-9
    • Fox KM; EURopean trial On reduction of cardiac events with Perindopril in stable coronary Artery disease Investigators. Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). Lancet 2003; 362:782-788. (Pubitemid 37093919)
    • (2003) Lancet , vol.362 , Issue.9386 , pp. 782-788
    • Fox, K.M.1
  • 13
    • 0035968623 scopus 로고    scopus 로고
    • Randomised trial of a perindopril-based bloodpressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack
    • PROGRESS Collaborative Group
    • PROGRESS Collaborative Group. Randomised trial of a perindopril-based bloodpressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001; 358:1033-1041.
    • (2001) Lancet , vol.358 , pp. 1033-1041
  • 17
    • 0035679426 scopus 로고    scopus 로고
    • Antihypertensive therapy in the elderly: The results of large trials
    • Leonetti G, Cuspidi C, Facchini M. [Antihypertensive therapy in the elderly: results of large trials]. Ital Heart J Suppl 2001; 2:1161-1169. (Pubitemid 34041353)
    • (2001) Italian Heart Journal Supplement , vol.2 , Issue.11 , pp. 1161-1169
    • Leonetti, G.1    Cuspidi, C.2    Facchini, M.3
  • 20
    • 34548420712 scopus 로고    scopus 로고
    • Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): A randomised controlled trial
    • DOI 10.1016/S0140-6736(07)61303-8, PII S0140673607613038
    • Patel A, MacMahon S, Chalmers J, Neal B, Woodward M, Billot L, Harrap S, Poulter N, Marre M, Cooper M, Glasziou P, Grobbee DE, Hamet P, Heller S, Liu LS, Mancia G, Mogensen CE, Pan CY, Rodgers A, Williams B; ADVANCE Collaborative Group. Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet 2007; 370:829-840. (Pubitemid 47362321)
    • (2007) Lancet , vol.370 , Issue.9590 , pp. 829-840
    • Patel, A.1
  • 21
    • 77955497132 scopus 로고    scopus 로고
    • Valsartan in elderly isolated systolic hypertension study group Target blood pressure for treatment of isolated systolic hypertension in the elderly: Valsartan in elderly isolated systolic hypertension study
    • Ogihara T, Saruta T, Rakugi H, Matsuoka H, Shimamoto K, Shimada K, Imai Y, Kikuchi K, Ito S, Eto T, Kimura G, Imaizumi T, Takishita S, Ueshima H; Valsartan in Elderly Isolated Systolic Hypertension Study Group. Target blood pressure for treatment of isolated systolic hypertension in the elderly: valsartan in elderly isolated systolic hypertension study. Hypertension 2010; 56:196-202.
    • (2010) Hypertension , vol.56 , pp. 196-202
    • Ogihara, T.1    Saruta, T.2    Rakugi, H.3    Matsuoka, H.4    Shimamoto, K.5    Shimada, K.6    Imai, Y.7    Kikuchi, K.8    Ito, S.9    Eto, T.10    Kimura, G.11    Imaizumi, T.12    Takishita, S.13    Ueshima, H.14
  • 22
    • 0023122783 scopus 로고
    • Benefits and potential harm of lowering high blood pressure
    • Cruickshank JM, Thorp JM, Zacharias FJ. Benefits and potential harm of lowering high blood pressure. Lancet 1987; 1:581-584.
    • (1987) Lancet , vol.1 , pp. 581-584
    • Cruickshank, J.M.1    Thorp, J.M.2    Zacharias, F.J.3
  • 23
    • 0037079309 scopus 로고    scopus 로고
    • Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies
    • DOI 10.1016/S0140-6736(02)11911-8
    • Lewington S, Clarke R, Qizilbash N, Peto R, Collins R; Prospective Studies Collaboration. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360:1903-1913. (Pubitemid 35472129)
    • (2002) Lancet , vol.360 , Issue.9349 , pp. 1903-1913
    • Lewington, S.1    Clarke, R.2    Qizilbash, N.3    Peto, R.4    Collins, R.5
  • 25
    • 0032513878 scopus 로고    scopus 로고
    • Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: Principal results of the Hypertension Optimal Treatment (HOT) randomised trial
    • DOI 10.1016/S0140-6736(98)04311-6
    • Hansson L, Zanchetti A, Carruthers SG, Dahlöf B, Elmfeldt D, Julius S, Ménard J, Rahn KH, Wedel H, Westerling S. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group. Lancet 1998; 351:1755-1762. (Pubitemid 28269185)
    • (1998) Lancet , vol.351 , Issue.9118 , pp. 1755-1762
    • Hansson, L.1    Zanchetti, A.2    Carruthers, S.G.3    Dahlof, B.4    Elmfeldt, D.5    Julius, S.6    Menard, J.7    Rahn, K.H.8    Wedel, H.9    Westerling, S.10
  • 26
    • 0032513936 scopus 로고    scopus 로고
    • J-curve not burned off by HOT study
    • DOI 10.1016/S0140-6736(98)22024-1
    • Kaplan N. J-curve not burned off by HOT study. Hypertension Optimal Treatment. Lancet 1998; 351:1748-1749. (Pubitemid 28269179)
    • (1998) Lancet , vol.351 , Issue.9118 , pp. 1748-1749
    • Kaplan, N.1
  • 27
    • 0037527647 scopus 로고    scopus 로고
    • European society of hypertension-European society of cardiology guidelines committee 2003 European society of Hypertension-European society of cardiology guidelines for the management of arterial hypertension
    • European Society of Hypertension-European Society of Cardiology Guidelines Committee. 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003; 21:1011-1053.
    • (2003) J Hypertens , vol.21 , pp. 1011-1053
  • 28
    • 0347423198 scopus 로고    scopus 로고
    • Joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. National heart, lung, and blood institute; National high blood pressure education program coordinating committee. Seventh report of the joint national committee on Prevention, detection, evaluation, and treatment of high blood pressure
    • Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003; 42:1206-1252.
    • (2003) Hypertension , vol.42 , pp. 1206-1252
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3    Cushman, W.C.4    Green, L.A.5    Izzo Jr., J.L.6    Jones, D.W.7    Materson, B.J.8    Oparil, S.9    Wright Jr., J.T.10    Roccella, E.J.11
  • 31
    • 33845343267 scopus 로고    scopus 로고
    • Grading evidence and recommendations for clinical practice guidelines in nephrology. A position statement from Kidney Disease: Improving Global Outcomes (KDIGO)
    • DOI 10.1038/sj.ki.5001875, PII 5001875
    • Uhlig K, Macleod A, Craig J, Lau J, Levey AS, Levin A, Moist L, Steinberg E, Walker R, Wanner C, Lameire N, Eknoyan G. Grading evidence and recommendations for clinical practice guidelines in nephrology. A position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int 2006; 70:2058-2065. (Pubitemid 44871367)
    • (2006) Kidney International , vol.70 , Issue.12 , pp. 2058-2065
    • Uhlig, K.1    MacLeod, A.2    Craig, J.3    Lau, J.4    Levey, A.S.5    Levin, A.6    Moist, L.7    Steinberg, E.8    Walker, R.9    Wanner, C.10    Lameire, N.11    Eknoyan, G.12
  • 33
    • 0027406191 scopus 로고
    • Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the multiple risk factor intervention trial
    • Stamler J, Vaccaro O, Neaton JD, Wentworth D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care 1993; 16:434-444. (Pubitemid 23046633)
    • (1993) Diabetes Care , vol.16 , Issue.2 , pp. 434-444
    • Stamler, J.1    Vaccaro, O.2    Neaton, J.D.3    Wentworth, D.4
  • 35
    • 0032511580 scopus 로고    scopus 로고
    • Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective diabetes study group
    • Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group. BMJ 1998; 317:703-713.
    • (1998) BMJ , vol.317 , pp. 703-713
  • 36
    • 67649651744 scopus 로고    scopus 로고
    • When should antihypertensive drug treatment be initiated and to what levels should systolic blood pressure be lowered? A critical reappraisal
    • Zanchetti A, Grassi G, Mancia G. When should antihypertensive drug treatment be initiated and to what levels should systolic blood pressure be lowered? A critical reappraisal. J Hypertens 2009; 27:923-934.
    • (2009) J Hypertens , vol.27 , pp. 923-934
    • Zanchetti, A.1    Grassi, G.2    Mancia, G.3
  • 37
    • 0037193819 scopus 로고    scopus 로고
    • Risk factor thresholds: Their existence under scrutiny
    • Law MR, Wald NJ. Risk factor thresholds: their existence under scrutiny. BMJ 2002; 324:1570-1576. (Pubitemid 34713139)
    • (2002) British Medical Journal , vol.324 , Issue.7353 , pp. 1570-1576
    • Law, M.R.1    Wald, N.J.2
  • 38
    • 0033610261 scopus 로고    scopus 로고
    • The role of diastolic blood pressure when treating isolated systolic hypertension
    • DOI 10.1001/archinte.159.17.2004
    • Somes GW, Pahor M, Shorr RI, Cushman WC, Applegate WB. The role of diastolic blood pressure when treating isolated systolic hypertension. Arch Intern Med 1999; 159:2004-2009. (Pubitemid 29453587)
    • (1999) Archives of Internal Medicine , vol.159 , Issue.17 , pp. 2004-2009
    • Somes, G.W.1    Pahor, M.2    Shorr, R.I.3    Cushman, W.C.4    Applegate, W.B.5
  • 42
    • 67649790352 scopus 로고    scopus 로고
    • ONTARGET investigators. Prognostic value of blood pressure in patients with high vascular risk in the Ongoing Telmisartan Alone and in combination with ramipril global endpoint trial study
    • Sleight P, Redon J, Verdecchia P, Mancia G, Gao P, Fagard R, Schumacher H, Weber M, Böhm M, Williams B, Pogue J, Koon T, Yusuf S; ONTARGET investigators. Prognostic value of blood pressure in patients with high vascular risk in the Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial study. J Hypertens 2009; 27:1360-1369.
    • (2009) J Hypertens , vol.27 , pp. 1360-1369
    • Sleight, P.1    Redon, J.2    Verdecchia, P.3    Mancia, G.4    Gao, P.5    Fagard, R.6    Schumacher, H.7    Weber, M.8    Böhm, M.9    Williams, B.10    Pogue, J.11    Koon, T.12    Yusuf, S.13
  • 43
  • 45
    • 0034700790 scopus 로고    scopus 로고
    • Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: Results of the HOPE study and MICRO-HOPE substudy heart outcomes prevention evaluation study investigators
    • Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators. Lancet 2000; 355:253-259.
    • (2000) Lancet , vol.355 , pp. 253-259
  • 48
    • 78649891370 scopus 로고    scopus 로고
    • Treating to new targets steering committee and investigators j-curve revisited: An analysis of blood pressure and cardiovascular events in the treating to new targets (TNT) Trial
    • Bangalore S, Messerli FH, Wun CC, Zuckerman AL, DeMicco D, Kostis JB, LaRosa JC; Treating to New Targets Steering Committee and Investigators. J-curve revisited: An analysis of blood pressure and cardiovascular events in the Treating to New Targets (TNT) Trial. Eur Heart J 2010; 31:2897-2908.
    • (2010) Eur Heart J , vol.31 , pp. 2897-2908
    • Bangalore, S.1    Messerli, F.H.2    Wun, C.C.3    Zuckerman, A.L.4    Demicco, D.5    Kostis, J.B.6    Larosa, J.C.7
  • 49
    • 78650170501 scopus 로고    scopus 로고
    • Prove it-timi 22 trial investigators. What is the optimal blood pressure in patients after acute coronary syndromes?: Relationship of blood pressure and cardiovascular events in the pravastatin or atorvastatin evaluation and infection therapy-thrombolysis in myocardial infarction (prove it-timi) 22 trial
    • Bangalore S, Qin J, Sloan S, Murphy SA, Cannon CP; PROVE IT-TIMI 22 Trial Investigators. What is the optimal blood pressure in patients after acute coronary syndromes?: Relationship of blood pressure and cardiovascular events in the PRavastatin OR atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction (PROVE IT-TIMI) 22 trial. Circulation 2010; 122:2142-2151.
    • (2010) Circulation , vol.122 , pp. 2142-2151
    • Bangalore, S.1    Qin, J.2    Sloan, S.3    Murphy, S.A.4    Cannon, C.P.5
  • 52
    • 0025783210 scopus 로고
    • Relation of low diastolic blood pressure to coronary heart disease death in presence of myocardial infarction: The Framingham Study
    • D'Agostino RB, Belanger AJ, Kannel WB, Cruickshank JM. Relation of low diastolic blood pressure to coronary heart disease death in presence of myocardial infarction: the Framingham Study. BMJ 1991; 303:385-389.
    • (1991) BMJ , vol.303 , pp. 385-389
    • D'Agostino, R.B.1    Belanger, A.J.2    Kannel, W.B.3    Cruickshank, J.M.4


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