Synthesis and structure of new bicopper(II) complexes bridged by N-(2- aminopropyl)-N′-(2-oxidophenyl)oxamide: The effects of terminal ligands on structures, anticancer activities and DNA-binding properties

European Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2011, Pages 3851-3857

  Li, Xiao Wen ^a   Zheng, Yong Jun ^a   Li, Yan Tuan ^a   Wu, Zhi Yong ^a   Yan, Cui Wei ^a  

^a OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

Bicopper(II) complexes; Crystal structure; Cytotoxicity; DNA interaction; Oxamido bridge

Indexed keywords

ANTINEOPLASTIC AGENT; BIPYRIDINE DERIVATIVE; COPPER; N (2 AMINOPROPYL) N' (2 OXIDO PHENYL)OXAMIDE; PHENANTHROLINE DERIVATIVE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; GEOMETRY; IC 50; X RAY CRYSTALLOGRAPHY;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COORDINATION COMPLEXES; COPPER; CRYSTALLOGRAPHY, X-RAY; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OXAMIC ACID; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; VISCOSITY;

EID: 80052952899     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.05.053     Document Type: Article

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