Potential AMPK activators of cucurbitane triterpenoids from Siraitia grosvenorii Swingle

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 19, 2011, Pages 5776-5781

  Chen, Xu Bing ^a   Zhuang, Jing Jing ^a   Liu, Jun Hua ^a   Lei, Min ^b   Ma, Lei ^a   Chen, Jing ^b   Shen, Xu ^a,b   Hu, Li Hong ^a,b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

AMPK; Anti diabetic effect; Cucurbitane triterpenoids; HepG2 cell; Siraitia grosvenorii Swingle

Indexed keywords

25 DEHYDROXY 24 OXOMOGROL; 25 METHOXY 11 OXOMOGROL; 25 METHOXYMOGROL; 3 HYDROXY 25 DEHYDROXY 24 OXOMOGROL; 3 HYDROXYMOGROL; ANTIDIABETIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ACTIVATOR; MOGROSIDE DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; ENERGY METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; INSULIN SENSITIVITY; MEDICINAL PLANT; PROTEIN PHOSPHORYLATION; PROTON NUCLEAR MAGNETIC RESONANCE; SIRAITIA GROSVENORII; SPECTROSCOPY;

AMP-ACTIVATED PROTEIN KINASES; CUCURBITACEAE; ENZYME ACTIVATION; ENZYME ACTIVATORS; FRUIT; GLYCOSIDES; HEP G2 CELLS; HUMANS; HYPOGLYCEMIC AGENTS; TRITERPENES;

RODENTIA; SIRAITIA GROSVENORII;

EID: 80052950548     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.08.030     Document Type: Article

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