Ferrocenyl chalcone difluoridoborates inhibit HIV-1 integrase and display low activity towards cancer and endothelial cells

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 20, 2011, Pages 6195-6197

  Monserrat, Jean Philippe ^a,b   Al Safi, Rasha I ^c   Tiwari, Keshri Nath ^a,b   Quentin, Lionel ^b,d,e,f   Chabot, Guy G ^b,d,e,f   Vessires, Anne ^a,b   Jaouen, Gérard ^a,b   Neamati, Nouri ^c   Hillard, Elizabeth A ^a,b  

^a PSL RESEARCH UNIVERSITY   (France)

^b CNRS   (France)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d PSL RESEARCH UNIVERSITY   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f INSERM   (France)

Author keywords

Boron; Chalcone; Cytotoxicity; Ferrocene; HIV

Indexed keywords

ANTINEOPLASTIC AGENT; BORIC ACID; CHALCONE DERIVATIVE; FERROCENE DERIVATIVE; FERROCENYL CHALCONE DIFLUORIDOBORATE DERIVATIVE; FLUORINE DERIVATIVE; INTEGRASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRUCTURE; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; ENDOTHELIUM CELL; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; STRUCTURE ACTIVITY RELATION;

BORATES; CELL LINE, TUMOR; CHALCONE; CHALCONES; HIV INFECTIONS; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 80052941912     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.07.078     Document Type: Article

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