Homozygosity mapping on homozygosity haplotype analysis to detect recessive disease-causing genes from a small number of unrelated, outbred patients

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Hagiwara, Koichi ^a   Morino, Hiroyuki ^b   Shiihara, Jun ^a   Tanaka, Tomoaki ^a   Miyazawa, Hitoshi ^a   Suzuki, Tomoko ^a   Kohda, Masakazu ^a   Okazaki, Yasushi ^a   Seyama, Kuniaki ^c   Kawakami, Hideshi ^b  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE FREQUENCY; GENE LOCUS; GENE MAPPING; GENE STRUCTURE; GENETIC ANALYSIS; GENOMIC FRAGMENT; HAPLOTYPE; HOMOZYGOSITY HAPLOTYPE; HOMOZYGOSITY MAPPING; HUMAN; OUTBREEDING; PHYLOGENY; POPULATION GENETICS; RECESSIVE GENE; SIIYAMA TYPE ALPHA 1 ANTITRYPSIN DEFICIENCY; ADULT; AGED; CASE CONTROL STUDY; CHROMOSOME MAP; COMPARATIVE STUDY; CONSANGUINITY; GENETICS; HOMOZYGOTE; MIDDLE AGED; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; ALPHA 1-ANTITRYPSIN DEFICIENCY; CASE-CONTROL STUDIES; CHROMOSOME MAPPING; CONSANGUINITY; GENES, RECESSIVE; HAPLOTYPES; HOMOZYGOTE; HUMANS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 80052931233     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025059     Document Type: Article

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