Pharmacokinetic characterization of decursinol derived from Angelica gigas Nakai in rats

Xenobiotica

Volumn 41, Issue 10, 2011, Pages 895-902

  Song, Jin Sook ^a,c   Chae, Jung Woo ^c   Lee, Kyeong Ryoon ^b   Lee, Byung Hoi ^a   Choi, Eun Jeong ^a   Ahn, Sung Hoon ^a   Kwon, Kwang Il ^c   Bae, Myung Ae ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

^b Seoul National University   (South Korea)

^c Chungnam National University   (South Korea)

Author keywords

Caco 2 cell permeability; Decursinol; metabolic stability; non linear pharmacokinetics; plasma protein binding

Indexed keywords

ANGELICA GIGAS EXTRACT; BREAST CANCER RESISTANCE PROTEIN; COUMARIN DERIVATIVE; DECURSINOL; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 2; PLASMA PROTEIN; UMBELLIFERONE; UNCLASSIFIED DRUG; VERAPAMIL;

ANGELICA; ANGELICA GIGAS; ANIMAL CELL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG GLUCURONIDATION; DRUG HALF LIFE; DRUG OXIDATION; DRUG PENETRATION; DRUG PROTEIN BINDING; DRUG STABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MAXIMUM PLASMA CONCENTRATION; MEDICINAL PLANT; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANGELICA; ANIMALS; BENZOPYRANS; BLOOD PROTEINS; BUTYRIC ACIDS; CACO-2 CELLS; HUMANS; RATS;

ANGELICA GIGAS; RATTUS;

EID: 80052897899     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2011.587551     Document Type: Article

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