Scale-up of a pharmaceutical roller compaction process using a joint-Y partial least squares model

Industrial and Engineering Chemistry Research

Volumn 50, Issue 18, 2011, Pages 10696-10706

  Liu, Zheng ^a   Bruwer, Mark John ^a   MacGregor, John F ^a   Rathore, Samarth S S ^b   Reed, David E ^b   Champagne, Marc J ^b  

^a PROSENSUS INC   (Canada)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DATA SETS; FITZPATRICK; KEY PROCESS; LABORATORY SCALE; LATENT VARIABLE REGRESSION; MASS FRACTION; PARTIAL LEAST SQUARES; PARTIAL LEAST SQUARES MODELS; PHARMACEUTICAL INDUSTRY; ROLLER COMPACTION; ROLLER COMPACTOR; SCALE-UP;

COMPACTION; CONSTRAINED OPTIMIZATION;

ROLLERS (MACHINE COMPONENTS);

EID: 80052856814     PISSN: 08885885     EISSN: 15205045     Source Type: Journal    
DOI: 10.1021/ie102316b     Document Type: Article

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