Uncertain progress on the fuzzy boundaries of alzheimer's disease: Reading between the guidelines

Journal of Alzheimer's Disease

Volumn 26, Issue 1, 2011, Pages 1-5

  Whitehouse, Peter J ^a   George, Daniel R ^b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; BIOLOGICAL MARKER;

AGING; ALZHEIMER DISEASE; AMNESIA; AMYLOID PLAQUE; AUTOPSY; COGNITION; COST BENEFIT ANALYSIS; DEATH; DISEASE ASSOCIATION; DISEASE MARKER; FUZZY LOGIC; HUMAN; MEDICAL SOCIETY; MEMORY; MILD COGNITIVE IMPAIRMENT; MULTIINFARCT DEMENTIA; NERVE CELL LESION; NEUROFIBRILLARY TANGLE; NEUROIMAGING; NEUROPATHOLOGY; PARKINSON DISEASE; PARKINSONISM; PRACTICE GUIDELINE; PRIORITY JOURNAL; PUBLICATION; REVIEW;

EID: 80052854739     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-111020     Document Type: Review

References (15)

1. Jack CR Jr, Albert MS, Knopman DS, McKhann GM, Sperling RA, Carrillo MC, Thies B, Phelps CH (2011) Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 257-262.
2. McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR Jr, Kawas CH, Klunk WE, Koroshetz WJ, Manly JJ, Mayeux R, Mohs RC, Morris JC, Rossor MN, Schel-tens P, Carrillo MC, Thies B, Weintraub S, Phelps CH (2011) The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 263-269.
3. Albert MS, Dekosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, Gamst A, Holtzman DM, Jagust WJ, Petersen RC, Snyder PJ, Carrillo MC, Thies B, Phelps CH (2011) The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 270-279.
4. Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, Iwatsubo T, Jack CR Jr, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, Yaffe K, Carrillo MC, Thies B, Morrison-Bogorad M, Wagster MV, Phelps CH (2011) Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 280-292.
5. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: Report ofthe NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34, 939-944. (Pubitemid 14076461)
6. Khachaturian Z (2011) Revised criteria for diagnosis of Alzheimer's disease: National Instituteon Aging-Alzheimer's Association diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 253-256.
7. D'Alton S, George DR (2011) Changing perspectives on Alzheimer's disease: thinking outside the amyloid box. J Alzheimers Dis, doi: 10.3233/JAD-2011- 110089.
8. Cummings J (2011) Biomarkers in Alzheimer's disease drug development. Alzheimers Dement 7, e13-e44.
9. Behuniak SM (2011) The living dead? The construction of people with Alzheimer's disease as zombies. Ageing Soc 31, 70-92.
10. George DR (2010) Overcoming the social death of dementia through language. Lancet 376, 586-587.
11. As one AA representative put it at a National Institute of Health State-of-the-Science Conference: Preventing Alzheimer's Disease and Cognitive Decline conference in 2010: "we are going to see in most of the cities in the world demented people wandering the streets because there is simply no place to put them, no way to prevent their dementia from occurring, and that's going to be a public health disaster that we just can't face up to."-Bill Thies NIH State-of-the-Science Conference: Preventing Alzheimer's Disease and Cognitive Decline-Day 3 (93:40 mark), http://videocast. nih.gov/summary.asp? Live=8412
12. Aquilina C, Hughes JC (2006) The return of the living dead: Agency lost and found? In Hughes JC, Louw SJ, Sabat SR (eds), Dementia: mind, meaning, and the person, Oxford University Press, Oxford, pp 143-161.
13. Lee HG, Zhu X, Nunomura A, Perry G, Smith MA (2006) Amyloid beta: The alternate hypothesis. Curr Alzheimer Res 3, 75-80.
14. Lee HG, Casadesus G, Zhu X, Takeda A, Perry G, Smith MA (2004) Challenging the amyloid cascade hypothesis: Senile plaques and amyloid-β as protective adaptations to Alzheimer disease. Ann NY Acad Sci 1019, 1-4. (Pubitemid 38951274)
15. Smith MA, Atwood CS, Joseph JA, Perry G (2002) Predicting the failure of amyloid-beta vaccine. Lancet 359, 1864-1865.