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Volumn 289, Issue 1, 2011, Pages 206-216

A mathematical framework for functional mapping of complex phenotypes using delay differential equations

Author keywords

Circadian rhythm; Delay differential equation; Functional mapping; Quantitative trait loci

Indexed keywords

MESSENGER RNA; PROTEIN;

EID: 80052848482     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2011.08.002     Document Type: Article
Times cited : (30)

References (31)
  • 1
    • 34249079154 scopus 로고    scopus 로고
    • Network motifs: theory and experimental approaches
    • Alon U. Network motifs: theory and experimental approaches. Nat. Rev. Genet. 2007, 8:450-461.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 450-461
    • Alon, U.1
  • 2
    • 35148895523 scopus 로고    scopus 로고
    • A cell cycle automaton model for probing circadian patterns of anticancer drug delivery
    • Altinok A., Lévi F., Goldbeter A. A cell cycle automaton model for probing circadian patterns of anticancer drug delivery. Adv. Drug Deliv. Rev. 2007, 59:1036-1053.
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 1036-1053
    • Altinok, A.1    Lévi, F.2    Goldbeter, A.3
  • 3
    • 0028151261 scopus 로고
    • Empirical threshold values for quantitative trait mapping
    • Churchill G.A., Doerge R.W. Empirical threshold values for quantitative trait mapping. Genetics 1994, 138:963-971.
    • (1994) Genetics , vol.138 , pp. 963-971
    • Churchill, G.A.1    Doerge, R.W.2
  • 5
    • 0029094843 scopus 로고
    • A model for circadian oscillations in the Drosophila period protein (PER)
    • Goldbeter A. A model for circadian oscillations in the Drosophila period protein (PER). Proc. R. Soc. London B 1995, 261:319-324.
    • (1995) Proc. R. Soc. London B , vol.261 , pp. 319-324
    • Goldbeter, A.1
  • 6
    • 0037079015 scopus 로고    scopus 로고
    • Computational approaches to cellular rhythms
    • Goldbeter A. Computational approaches to cellular rhythms. Nature 2002, 420:238-245.
    • (2002) Nature , vol.420 , pp. 238-245
    • Goldbeter, A.1
  • 7
    • 4143103719 scopus 로고    scopus 로고
    • Computational biology: a propagating wave of interest
    • Goldbeter A. Computational biology: a propagating wave of interest. Curr. Biol. 2004, 14:601-602.
    • (2004) Curr. Biol. , vol.14 , pp. 601-602
    • Goldbeter, A.1
  • 8
    • 0034092789 scopus 로고    scopus 로고
    • Theoretical models for circadian rhythms in Neurospora and Drosophila
    • Gonze D., Leloup J.C., Goldbeter A. Theoretical models for circadian rhythms in Neurospora and Drosophila. Life Sci. 2000, 323:57-67.
    • (2000) Life Sci. , vol.323 , pp. 57-67
    • Gonze, D.1    Leloup, J.C.2    Goldbeter, A.3
  • 9
    • 0037336350 scopus 로고    scopus 로고
    • Integration from proteins to organs: the physiome project
    • Hunter P.J., Borg T.K. Integration from proteins to organs: the physiome project. Nat. Rev. Mol. Cell. Biol. 2003, 4:237-243.
    • (2003) Nat. Rev. Mol. Cell. Biol. , vol.4 , pp. 237-243
    • Hunter, P.J.1    Borg, T.K.2
  • 10
    • 5044229321 scopus 로고    scopus 로고
    • The impact of systems approaches on biological problems in drug discovery
    • Hood L., Perlmutter R.M. The impact of systems approaches on biological problems in drug discovery. Nat. Biotechnol. 2004, 22:1215-1217.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1215-1217
    • Hood, L.1    Perlmutter, R.M.2
  • 11
    • 0034042294 scopus 로고    scopus 로고
    • Molecular genetics of circadian rhythms in mammals
    • King D.P., Takahashi J.S. Molecular genetics of circadian rhythms in mammals. Annu. Rev. Neurosci. 2000, 23:713-742.
    • (2000) Annu. Rev. Neurosci. , vol.23 , pp. 713-742
    • King, D.P.1    Takahashi, J.S.2
  • 12
    • 0346041902 scopus 로고    scopus 로고
    • Computational modelling of biological systems: tools and visions
    • Kohl P., Noble D., Winslow R., Hunter P.J. Computational modelling of biological systems: tools and visions. Philos. Trans. R. Soc. A 2000, 358:579-610.
    • (2000) Philos. Trans. R. Soc. A , vol.358 , pp. 579-610
    • Kohl, P.1    Noble, D.2    Winslow, R.3    Hunter, P.J.4
  • 13
  • 14
    • 77950851502 scopus 로고    scopus 로고
    • Functional mapping of growth and development
    • Li Y., Wu R.L. Functional mapping of growth and development. Biol. Rev. 2010, 85:207-216.
    • (2010) Biol. Rev. , vol.85 , pp. 207-216
    • Li, Y.1    Wu, R.L.2
  • 15
    • 33847222481 scopus 로고    scopus 로고
    • A computational model for functional mapping of genes that regulate intracellular circadian rhythms
    • Liu T., Liu X., Chen Y.M., Wu R.L. A computational model for functional mapping of genes that regulate intracellular circadian rhythms. Theor. Biol. Med. Model. 2007, 1:19.
    • (2007) Theor. Biol. Med. Model. , vol.1 , pp. 19
    • Liu, T.1    Liu, X.2    Chen, Y.M.3    Wu, R.L.4
  • 16
    • 77952292257 scopus 로고    scopus 로고
    • A differential equation model for functional mapping of a virus-cell dynamic system
    • Luo J.T., Hager W.W., WU R.L. A differential equation model for functional mapping of a virus-cell dynamic system. J. Math. Biol. 2010, 61:1-15.
    • (2010) J. Math. Biol. , vol.61 , pp. 1-15
    • Luo, J.T.1    Hager, W.W.2    Wu, R.L.3
  • 17
    • 0036671301 scopus 로고    scopus 로고
    • Functional mapping of quantitative trait loci underlying the character process: a theoretical framework
    • Ma C.X., Casella G., Wu R.L. Functional mapping of quantitative trait loci underlying the character process: a theoretical framework. Genetics 2002, 161:1751-1762.
    • (2002) Genetics , vol.161 , pp. 1751-1762
    • Ma, C.X.1    Casella, G.2    Wu, R.L.3
  • 19
    • 0036499997 scopus 로고    scopus 로고
    • Modeling the heat-from genes to cells to the whole organ
    • Noble D. Modeling the heat-from genes to cells to the whole organ. Science 2002, 295:1678-1682.
    • (2002) Science , vol.295 , pp. 1678-1682
    • Noble, D.1
  • 20
    • 38349016564 scopus 로고    scopus 로고
    • Modelling periodic oscillations during somitogenesis
    • Peng F., Navaratna M. Modelling periodic oscillations during somitogenesis. Math. Biosci. Eng. 2007, 4:661-673.
    • (2007) Math. Biosci. Eng. , vol.4 , pp. 661-673
    • Peng, F.1    Navaratna, M.2
  • 21
    • 0013458618 scopus 로고    scopus 로고
    • A mathematical model for the intracellular circadian rhythm generator
    • Scheper T.O., klinkenberg D., Pennartz C., Pelt J.V. A mathematical model for the intracellular circadian rhythm generator. J. Neurosci. 1999, 19:40-47.
    • (1999) J. Neurosci. , vol.19 , pp. 40-47
    • Scheper, T.O.1    klinkenberg, D.2    Pennartz, C.3    Pelt, J.V.4
  • 22
    • 0033822171 scopus 로고    scopus 로고
    • Circadian rhythm genetics: from flies to mice to humans
    • Smith K.W., Kay S.A. Circadian rhythm genetics: from flies to mice to humans. Nat. Genet. 2000, 26:23-27.
    • (2000) Nat. Genet. , vol.26 , pp. 23-27
    • Smith, K.W.1    Kay, S.A.2
  • 23
    • 4544219781 scopus 로고    scopus 로고
    • Finding new clock components: past and future
    • Takhashi J.S. Finding new clock components: past and future. J. Biol. Rhythms 2004, 19:339-347.
    • (2004) J. Biol. Rhythms , vol.19 , pp. 339-347
    • Takhashi, J.S.1
  • 24
    • 4444250752 scopus 로고    scopus 로고
    • A statistical model for high-resolution mapping of quantitative trait loci determining HIV dynamics
    • Wang Z.H., Wu R.L. A statistical model for high-resolution mapping of quantitative trait loci determining HIV dynamics. Stat. Med. 2004, 23:3033-3051.
    • (2004) Stat. Med. , vol.23 , pp. 3033-3051
    • Wang, Z.H.1    Wu, R.L.2
  • 25
    • 0036188948 scopus 로고    scopus 로고
    • Joint linkage and linkage diseuilibrium mapping of quantitative trait loci in natural populations
    • Wu R.L., Ma C.X., Casella G. Joint linkage and linkage diseuilibrium mapping of quantitative trait loci in natural populations. Genetics 2002, 160:779-792.
    • (2002) Genetics , vol.160 , pp. 779-792
    • Wu, R.L.1    Ma, C.X.2    Casella, G.3
  • 26
    • 1942517853 scopus 로고    scopus 로고
    • A general framework for analyzing the genetic architecture of developmental characteristics
    • Wu R.L., Ma C.X., Lin M., Casella G. A general framework for analyzing the genetic architecture of developmental characteristics. Genetics 2004, 166:1541-1551.
    • (2004) Genetics , vol.166 , pp. 1541-1551
    • Wu, R.L.1    Ma, C.X.2    Lin, M.3    Casella, G.4
  • 27
    • 1942530537 scopus 로고    scopus 로고
    • Functional mapping of growth quantitative trait loci using a transform-both-sides logistic model
    • Wu R.L., Ma C.X., Lin M., Wang Z.H., Casella G. Functional mapping of growth quantitative trait loci using a transform-both-sides logistic model. Biometrics 2004, 60:729-738.
    • (2004) Biometrics , vol.60 , pp. 729-738
    • Wu, R.L.1    Ma, C.X.2    Lin, M.3    Wang, Z.H.4    Casella, G.5
  • 28
    • 11244324001 scopus 로고    scopus 로고
    • A mechanistic model for genetic machinery of ontogenetic growth
    • Wu R.L., Wang Z.H., Zhao W., Cheverud J.M. A mechanistic model for genetic machinery of ontogenetic growth. Genetics 2004, 168:2383-2394.
    • (2004) Genetics , vol.168 , pp. 2383-2394
    • Wu, R.L.1    Wang, Z.H.2    Zhao, W.3    Cheverud, J.M.4
  • 29
    • 33644845428 scopus 로고    scopus 로고
    • Functional mapping-how to map and study the genetic architecture of dynamic complex traits
    • Wu R.L., Lin M. Functional mapping-how to map and study the genetic architecture of dynamic complex traits. Nat. Rev. Genet. 2006, 7:229-237.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 229-237
    • Wu, R.L.1    Lin, M.2
  • 30
    • 4444290291 scopus 로고    scopus 로고
    • A fast algorithm for functional mapping of complex traits
    • Zhao W., Wu R.L., Ma C.X., Casella G. A fast algorithm for functional mapping of complex traits. Genetics 2004, 167:2133-2137.
    • (2004) Genetics , vol.167 , pp. 2133-2137
    • Zhao, W.1    Wu, R.L.2    Ma, C.X.3    Casella, G.4
  • 31
    • 28044473632 scopus 로고    scopus 로고
    • Structured antedependence models for functional mapping of multiple longitudinal traits
    • Zhao W., Hou W., Littell R.C., Wu R.L. Structured antedependence models for functional mapping of multiple longitudinal traits. Stat. Appl. Genet. Mol. Biol. 2005, 4(1):26.
    • (2005) Stat. Appl. Genet. Mol. Biol. , vol.4 , Issue.1 , pp. 26
    • Zhao, W.1    Hou, W.2    Littell, R.C.3    Wu, R.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.