Individuals with sessile serrated polyps express an aggressive colorectal phenotype

Diseases of the Colon and Rectum

Volumn 54, Issue 10, 2011, Pages 1216-1223

  Vu, Hongha T ^a   Lopez, Rocio ^a   Bennett, Ana ^a   Burke, Carol A ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Colorectal cancer; Serrated pathway; Sessile serrated adenoma; Sessile serrated polyp

Indexed keywords

ANTINEOPLASTIC AGENT;

ADENOMATOUS POLYP; ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; COLON ADENOMA; COLON POLYP; COLONOSCOPY; COLORECTAL CANCER; DEMOGRAPHY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; POLYPECTOMY; RECURRENT CANCER; RETROSPECTIVE STUDY; SESSILE SERRATED POLYP; SIGMOIDOSCOPY; TUBULOVILLOUS ADENOMA; VILLOUS ADENOMA;

ADENOMA; AGED; ANALYSIS OF VARIANCE; BODY MASS INDEX; COLONIC POLYPS; COLONOSCOPY; COLORECTAL NEOPLASMS; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; PRECANCEROUS CONDITIONS; RETROSPECTIVE STUDIES; SMOKING;

EID: 80052777038     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1097/DCR.0b013e318228f8a9     Document Type: Article

References (25)

1. O'Brien MJ, Yang S, Mack C, et al. Comparison of microsatellite instability, CpGisland methylation phenotype, BRAF and KRAS statusin serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points. Am J Surg Pathol. 2006;30:1491-1501. (Pubitemid 44808785)
2. O'Brien MJ. Hyperplastic and serrated polyps of the colorectum. Gastroenterol Clin North Am. 2007;36:947-968. (Pubitemid 350064454)
3. Urbanski SJ, Kossakowska AE, Marcon N, et al. Mixed hyper-plastic adenomatous polyps - an underdiagnosed entity: report of a case of adenocarcinoma arising within a mixed hyperplastic adenomatous polyp. Am J Surg Pathol. 1984;8:551-556. (Pubitemid 14083982)
4. Longacre TA, Fenoglio-Preiser CM. Mixed hyperplastic adenomatous polyps/serrated adenomas: a distinct form of colorectal neoplasia. Am J Surg Pathol. 1990;14:524-537. (Pubitemid 20172523)
5. Torlakovic E, Skovlund E, Snover DC, et al. Morphologic reappraisal of serrated colorectal polyps. Am J Surg Pathol. 2003;27: 65-81. (Pubitemid 36014900)
6. Spring KJ, Zhao ZZ, Karamatic R, et al. High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy. Gastroenterology. 2006;131:1400-1407. (Pubitemid 44708940)
7. Torlakovic E, Snover DC. Serrated adenomatous polyposis in humans. Gastroenterology. 1996;110:748-755. (Pubitemid 26071842)
8. Goldstein NS, Bhanot P, Odish E, et al. Hyperplastic-like colon polyps that preceded microsatellite-unstable adenocarcinomas. Am J Clin Pathol. 2003;119:778-796. (Pubitemid 37047838)
9. Li D, Jin C, McCulloch C, et al. Association of large serrated polyps with synchronous advanced colorectal neoplasia. Am J Gastroenterol. 2009;104:695-702.
10. Lazarus R, Junttila OE, Karttunen TJ, et al. The risk of metachronous neoplasia in patients with serrated adenoma. Am J Clin Pathol. 2005;123:349-359. (Pubitemid 40315075)
11. Lu FI, van Niekerk DW, Owen D, et al. Longitudinal outcome study of sessile serrated adenomas of the colorectum: an increased risk for subsequent right-sided colorectal carcinoma. Am J Surg Pathol. 2010;34:927-934.
12. Gurudu S, Heigh E, Heigh R, et al. Sessile serrated adenomas: demographic, clinical and endoscopic characteristics in a patient population. Am J Gastroenterol. 2008;103:S177.
13. Lash R, Schuler C, Genta R. Demographic and pathologic evaluation of 2139 patients with sessile serrated adenomas in a one-year period. Am J Gastroenterol. 2008;103:S191.
14. Martinez ME, Baron JA, Lieberman DA, et al. A pooled analysis of advanced colorectal neoplasia diagnoses after colonoscopic polypectomy. Gastroenterology. 2009;136:832-841.
15. Schreiner MA, Weiss DG, Lieberman DA. Proximal and large hyperplastic and nondysplastic serrated polyps detected by colonoscopy are associated with neoplasia. Gastroenterology. 2010;139:1497-1502.
16. Jass JR. Serrated route to colorectal cancer: back street or super highway? J Pathol. 2001;193:283-285. (Pubitemid 32229857)
17. Goldstein NS. Small colonic microsatellite unstable adenocarcinomas and high-grade epithelial dysplasias in sessile serrated adenoma polypectomy specimens: a study of eight cases. Am J Clin Pathol. 2006;125:132-145. (Pubitemid 43089736)
18. Oono Y, Fu K, Nakamura H, et al. Progression of a sessile serrated adenoma to an early invasive cancer within 8 months. Dig Dis Sci. 2009;54:906-909.
19. Spring KJ, Zhao ZZ, Karamatic R, et al. High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy. Gastroenterology. 2006;131:1400-1407. (Pubitemid 44708940)
20. Pai RK, Hart J, Noffsinger AE. Sessile serrated adenomas strongly predispose to synchronous serrated polyps in non-syndromic patients. Histopathology. 2010;56:581-588.
21. Pai RK, Mackinnon AC, Joseph L, et al. Identification of histologically distinct conventional adenomas that arise predominately in patients with sessile serrated adenomas. Am J Surg Pathol. 2010;34:355-363.
22. Winawer SJ, Zauber AG, Fletcher RH, et al. Guidelines for colonoscopy surveillance after polypectomy: aconsensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society. Gastroenterology. 2006;130:1872-1885. (Pubitemid 43668826)
23. Groff RJ, Nash R, Ahnen DJ. Significance of serrated polyps of the colon. Curr Gastroenterol Rep. 2008;10:490-498.
24. Kahi CJ, Rex DK, Imperiale TF. Screening, surveillance, and primary prevention for colorectal cancer: a review of the recent literature. Gastroenterology. 2008;135:380-399.
25. East JE, Saunders BP, Jass JR. Sporadic and syndromic hyperplastic polyps and serrated adenomas of the colon: classification, molecular genetics, natural history, and clinical management. Gastroenterol Clin North Am. 2008;37:25-46. (Pubitemid 351289032)