The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters

EMBO Journal

Volumn 30, Issue 18, 2011, Pages 3786-3798

  Costessi, Adalberto ^a   Mahrour, Nawel ^b   Tijchon, Esther ^a   Stunnenberg, Rieka ^a   Stoel, Marieke A ^a   Jansen, Pascal W ^a   Sela, Dotan ^b   Martin Brown, Skylar ^b   Washburn, Michael P ^b,c   Florens, Laurence ^b   Conaway, Joan W ^b,d   Conaway, Ronald C ^b,d   Stunnenberg, Hendrik G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

Cullin2; NFY; PRAME; transcription; ubiquitination

Indexed keywords

CULLIN; DNA; NUCLEAR FACTOR Y; PREFERENTIALLY EXPRESSED ANTIGEN OF MELANOMA; TUMOR ANTIGEN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENETIC TRANSCRIPTION; GENOME; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR RECOGNITION; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PURIFICATION; TRANSCRIPTION REGULATION;

ANTIGENS, NEOPLASM; CCAAT-BINDING FACTOR; CHROMATIN IMMUNOPRECIPITATION; CULLIN PROTEINS; HUMANS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN SUBUNITS; UBIQUITIN-PROTEIN LIGASES;

EID: 80052770792     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.262     Document Type: Article

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