-
1
-
-
0034899540
-
ADMET-turning chemicals into drugs
-
Hodgson J. ADMET-turning chemicals into drugs. Nat Biotechnol 2001; 19:722-726.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 722-726
-
-
Hodgson, J.1
-
2
-
-
70449136457
-
Drug reactions enzymes, and biochemical genetics
-
Motulsky AG. Drug reactions enzymes, and biochemical genetics. J Am Med Assoc 1957; 165:835-837.
-
(1957)
J Am Med Assoc
, vol.165
, pp. 835-837
-
-
Motulsky, A.G.1
-
3
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 1994; 270:414-423. (Pubitemid 24229655)
-
(1994)
Journal of Pharmacology and Experimental Therapeutics
, vol.270
, Issue.1
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
5
-
-
80052765259
-
Dangerous liaisons
-
May
-
Bode Chris. Dangerous Liaisons, THE SCIENTIST, May 2010, 38-43.
-
(2010)
The Scientist
, pp. 38-43
-
-
Chris, B.1
-
6
-
-
0037259315
-
Incidence of idiopathic acute liver failure and hospitalized liver injury in patients treated with troglitazone
-
DOI 10.1111/j.1572-0241.2003.07175.x, PII S0002927002058434
-
Graham DJ, Drinkard CR, Shatin D. Incidence of idiopathic acute liver failure and hospitalized liver injury in patients treated with troglitazone. Am J Gastroenterol 2003; 98:175-179. (Pubitemid 36135187)
-
(2003)
American Journal of Gastroenterology
, vol.98
, Issue.1
, pp. 175-179
-
-
Graham, D.J.1
Drinkard, C.R.2
Shatin, D.3
-
7
-
-
0037353404
-
Troglitazone-induced liver failure: A case study
-
DOI 10.1016/S0002-9343(02)01529-2
-
Graham DJ, Green L, Senior JR, Graham DJ, Green L, Senior JR, Nourjah P, et al. Troglitazone-induced liver failure: a case study. Am J Med 2003; 114:299-306. (Pubitemid 36398076)
-
(2003)
American Journal of Medicine
, vol.114
, Issue.4
, pp. 299-306
-
-
Graham, D.J.1
Green, L.2
Senior, J.R.3
Nourjah, P.4
-
8
-
-
0029125984
-
Metabolism of drugs by cytochrome P450 3A isoforms. Implications for drug interactions in psychopharmacology
-
von Moltke LL, Greenblatt DJ, Schmider J, Harmatz JS, Shader RI. Metabolism of drugs by cytochrome P450 3A isoforms. Implications for drug interactions in psychopharmacology. Clin Pharmacokinet 1995; 29:43-44.
-
(1995)
Clin Pharmacokinet
, vol.29
, pp. 43-44
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Schmider, J.3
Harmatz, J.S.4
Shader, R.I.5
-
9
-
-
3242709450
-
Pharmacokinetic interactions of drugs with St John's wort
-
DOI 10.1177/0269881104042632
-
Zhou S, Chan E, Pan SQ, Huang M, Lee EJ. Pharmacokinetic interactions of drugs with St John's Wort. J Psychopharmacol 2004; 18:262-276. (Pubitemid 38954916)
-
(2004)
Journal of Psychopharmacology
, vol.18
, Issue.2
, pp. 262-276
-
-
Zhou, S.1
Chan, E.2
Pan, S.-Q.3
Huang, M.4
Lee, E.J.D.5
-
10
-
-
0141542650
-
Effect of mibefradil on CYP3A4 in vivo
-
DOI 10.1177/0091270003256687
-
Veronese ML, Gillen LP, Dorval EP, Hauck WW, Waldman SA, Greenberg HA. Effect of mibefradil on CYP3A4 in vivo. J Clin Pharmacol 2003; 43:1091-1100. (Pubitemid 37174440)
-
(2003)
Journal of Clinical Pharmacology
, vol.43
, Issue.10
, pp. 1091-1100
-
-
Veronese, M.L.1
Gillen, L.P.2
Dorval, E.P.3
Hauck, W.W.4
Waldman, S.A.5
Greenberg, H.E.6
-
11
-
-
0035071598
-
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
DOI 10.1038/86882
-
Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet 2001; 27:383-391. (Pubitemid 32268418)
-
(2001)
Nature Genetics
, vol.27
, Issue.4
, pp. 383-391
-
-
Kuehl, P.1
Zhang, J.2
Lin, Y.3
Lamba, J.4
Assem, M.5
Schuetz, J.6
Watkins, P.B.7
Daly, A.8
Wrighton, S.A.9
Hall, S.D.10
Maurel, P.11
Relling, M.12
Brimer, C.13
Yasuda, K.14
Venkataramanan, R.15
Strom, S.16
Thummel, K.17
Boguski, M.S.18
Schuetz, E.19
-
12
-
-
54249101311
-
Cytochrome P450 induction by rifampicin in health subjects: Determination using the Karolinska cocktail and the endogenous CYP3A4 biomarker 4b-hydroxycholesterol
-
Kanebratt KP, Diczfalusy U, Backstrom T, Sparve E, Bredberg E, Bottiger Y, et al. Cytochrome P450 induction by rifampicin in health subjects: determination using the Karolinska cocktail and the endogenous CYP3A4 biomarker 4b-hydroxycholesterol. Clin Pharmacol Ther 2008; 84:589-594.
-
(2008)
Clin Pharmacol Ther
, vol.84
, pp. 589-594
-
-
Kanebratt, K.P.1
Diczfalusy, U.2
Backstrom, T.3
Sparve, E.4
Bredberg, E.5
Bottiger, Y.6
-
13
-
-
72749115675
-
St John's Wort (Hypericum perforatum) in major depression
-
Shelton RC St. John's Wort (Hypericum perforatum) in major depression. J Clin Psychiatry 2009; 70:23-27.
-
(2009)
J Clin Psychiatry
, vol.70
, pp. 23-27
-
-
Shelton, R.C.1
-
14
-
-
68949110071
-
St John's Wort-an overview
-
Linde K. St. John's Wort-an overview. Forsch Komplementmed 2009; 16:146-155.
-
(2009)
Forsch Komplementmed
, vol.16
, pp. 146-155
-
-
Linde, K.1
-
15
-
-
0034076445
-
St John's Wort: Effect on CYP3A4 activity
-
Roby CA, Anderson GD, Kantor E, Dryer D, Burstein AH. St. John's Wort: effect on CYP3A4 activity. Clin Pharmacol Ther 2000; 67:451-457. (Pubitemid 30327483)
-
(2000)
Clinical Pharmacology and Therapeutics
, vol.67
, Issue.5
, pp. 451-457
-
-
Roby, C.A.1
Anderson, G.D.2
Kantor, E.3
Dryer, D.A.4
Burstein, A.H.5
-
16
-
-
0037131879
-
Genetic contribution to variable human CYP3A-mediated metabolism
-
DOI 10.1016/S0169-409X(02)00066-2, PII S0169409X02000662
-
Lamba JK, Lin YS, Schuetz EG, Thummel KE. Genetic contribution to variable human CYP3A-mediated metabolism. Adv Drug Deliv Rev 2002; 54:1271-1294. (Pubitemid 35284253)
-
(2002)
Advanced Drug Delivery Reviews
, vol.54
, Issue.10
, pp. 1271-1294
-
-
Lamba, J.K.1
Lin, Y.S.2
Schuetz, E.G.3
Thummel, K.E.4
-
17
-
-
0020594132
-
Quinine disposition kinetics
-
White NJ, Chanthavanich P, Krishna S, Bunch C, Silamut K. Quinine disposition kinetics. Br J Clin Pharmacol 1983; 16:399-403. (Pubitemid 13015764)
-
(1983)
British Journal of Clinical Pharmacology
, vol.16
, Issue.4
, pp. 399-403
-
-
White, N.J.1
Chanthavanich, P.2
Krishna, S.3
-
18
-
-
0032726752
-
The roles of cytochrome P450 3A4 and 1A2 in the 3-hydroxylation of quinine
-
Mirghani RA, Hellgren U, Westerberg PA, Ericsson O, Bertilsson L, Gustafsson LL. The roles of cytochrome P450 3A4 and 1A2 in the 3-hydroxylation of quinine. Br J Clin Pharmacol Ther 1999; 66:454-460.
-
(1999)
Br J Clin Pharmacol Ther
, vol.66
, pp. 454-460
-
-
Mirghani, R.A.1
Hellgren, U.2
Westerberg, P.A.3
Ericsson, O.4
Bertilsson, L.5
Gustafsson, L.L.6
-
19
-
-
80052780348
-
Enzyme kinetics for the formation of 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway
-
Mirghani RA, Yasar U, Zheng T, Cook JM, Gustafsson LL, Tybring G, Ericsson O. Enzyme kinetics for the formation of 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway. Drug Metab Dispos 2002; 30:1268-1371.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1268-1371
-
-
Mirghani, R.A.1
Yasar, U.2
Zheng, T.3
Cook, J.M.4
Gustafsson, L.L.5
Tybring, G.6
Ericsson, O.7
-
20
-
-
0038807786
-
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man
-
Mirghani RA, Ericsson O, Tybring G, Gustafsson LL, Bertilsson L. Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man. Eur J Clin Pharmacol 2003; 59:23-28. (Pubitemid 36702755)
-
(2003)
European Journal of Clinical Pharmacology
, vol.59
, Issue.1
, pp. 23-28
-
-
Mirghani, R.A.1
Ericsson, O.2
Tybring, G.3
Gustafsson, L.L.4
Bertilsson, L.5
-
21
-
-
0038548118
-
The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes
-
DOI 10.1016/S0009-9236(03)00050-X
-
Christensen M, Andersson K, Dalen P, Mirghani RA, Muirhead GJ, Nordmark A, et al. The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes. Clin Pharmacol Ther 2003; 73:517-528. (Pubitemid 37249122)
-
(2003)
Clinical Pharmacology and Therapeutics
, vol.73
, Issue.6
, pp. 517-528
-
-
Christensen, M.1
Andersson, K.2
Dalen, P.3
Mirghani, R.A.4
Muirhead, G.J.5
Nordmark, A.6
Tybring, G.7
Wahlberg, A.8
Yasar, U.9
Bertilsson, L.10
-
22
-
-
40049103597
-
4β-Hydroxycholesterol is a new endogenous CYP3A marker: Relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians
-
DOI 10.1097/FPC.0b013e3282f50ee9, PII 0121301120080300000004
-
Diczfalusy U, Muira J, Roh HK, Mirghani RA, Sayi J, Bertilsson L, et al. 4bhydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians. Pharmacogenet Genomics 2008; 18:201-208. (Pubitemid 351323234)
-
(2008)
Pharmacogenetics and Genomics
, vol.18
, Issue.3
, pp. 201-208
-
-
Diczfalusy, U.1
Miura, J.2
Roh, H.-K.3
Mirghani, R.A.4
Sayi, J.5
Larsson, H.6
Bodin, K.G.7
Allqvist, A.8
Jande, M.9
Kim, J.-W.10
Aklillu, E.11
Gustafsson, L.L.12
Bertilsson, L.13
-
23
-
-
0035871924
-
Simultaneous determination of quinine and four metabolites in plasma and urine by high-performance liquid chromatography
-
DOI 10.1016/S0378-4347(00)00577-6, PII S0378434700005776
-
Mirghani RA, Ericsson O, Cook J, Yu P, Gustafsson LL. Simultaneous determination of quinine and four metabolites in plasma and urine by highperformance liquid chromatography. J Chromatogr B Biomed Sci Appl 2001; 754:57-64. (Pubitemid 32241068)
-
(2001)
Journal of Chromatography B: Biomedical Sciences and Applications
, vol.754
, Issue.1
, pp. 57-64
-
-
Mirghani, R.A.1
Ericsson, O.2
Cook, J.3
Yu, P.4
Gustafsson, L.L.5
-
24
-
-
79953177827
-
Rapid quantification of quinine and its major metabolite 3-hydroxyquinine in diluted urine by UPLC-MS/MS
-
Heaton J, Rahmioglu N, Ahmadi KR, Legido-Quigley C, Smith NW. Rapid quantification of quinine and its major metabolite 3-hydroxyquinine in diluted urine by UPLC-MS/MS. J Pharm Biomed 2011; 55:494-499.
-
(2011)
J Pharm Biomed
, vol.55
, pp. 494-499
-
-
Heaton, J.1
Rahmioglu, N.2
Ahmadi, K.R.3
Legido-Quigley, C.4
Smith, N.W.5
-
25
-
-
0002921254
-
Generalisability and assumption of twin studies
-
Spector TD Sneider H Macgregor AJ editors. Advances in twin and sib-pair analysis London: Greenwich Medical Media
-
Kyvik KO. Generalisability and assumption of twin studies. Advances in twin and sib-pair analysis. In: Spector TD, Sneider H, Macgregor AJ, editors. Advances in twin and sib-pair analysis. 2000; London: Greenwich Medical Media; pp. 67-77.
-
(2000)
Advances in Twin and Sib-pair Analysis
, pp. 67-77
-
-
Kyvik, K.O.1
-
27
-
-
0024523831
-
Pharmacogenetic perspectives gained from twin and family studies
-
DOI 10.1016/0163-7258(89)90130-7
-
Vesell ES. Pharmacogenetic perspectives gained from twin and family studies. Pharmacol Ther 1989; 41:535-552. (Pubitemid 19102462)
-
(1989)
Pharmacology and Therapeutics
, vol.41
, Issue.3
, pp. 535-552
-
-
Vesell, E.S.1
-
28
-
-
0031826288
-
Hypothesis: Comparisons of inter- and intra-individual variations can substitute for twin studies in drug research
-
DOI 10.1097/00008571-199808000-00001
-
Kalow W, Endrenyi L, Tang BK. Hypothesis: comparisons of inter and intraindividual variations can substitute for twin studies in drug research. Pharmacogenetics 1998; 8:283-289. (Pubitemid 28372321)
-
(1998)
Pharmacogenetics
, vol.8
, Issue.4
, pp. 283-289
-
-
Kalow, W.1
Tang, B.-K.2
Endrenyi, L.3
-
29
-
-
0000783041
-
Evaluation of the genetic component of variability in CYP3A4 activity: A repeated drug administration method
-
DOI 10.1097/00008571-200007000-00001
-
Ozdemir V,Werner K, Bing-Kou T, Paterson AD,Walker SE, Endrenyi L, et al. Evaluation of the genetic component of variability in CYP3A4 activity drug administration method. Pharmacogenetics 2000; 10:373-388. (Pubitemid 30433571)
-
(2000)
Pharmacogenetics
, vol.10
, Issue.5
, pp. 373-388
-
-
Ozdemir, V.1
Kalow, W.2
Tang, B.-K.3
Paterson, A.D.4
Walker, S.E.5
Endrenyi, L.6
Kashuba, A.D.M.7
-
30
-
-
0035914368
-
Antiepileptic drugs increase plasma levels of 4b-hydroxycholesterol in humans
-
Bodin K, Bretillon L, Aden Y, Bertilsson L, Broome U, Einarsson C, et al. Antiepileptic drugs increase plasma levels of 4b-hydroxycholesterol in humans. J Biol Chem 2001; 276:38685-38689.
-
(2001)
J Biol Chem
, vol.276
, pp. 38685-38689
-
-
Bodin, K.1
Bretillon, L.2
Aden, Y.3
Bertilsson, L.4
Broome, U.5
Einarsson, C.6
-
31
-
-
42149130238
-
Time course of the increase in 4β-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy
-
DOI 10.1111/j.1365-2125.2007.03078.x
-
Wide K, Larsson H, Bertilsson L, Diczfalusy U. Time course of the increase in 4b-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy. Br J Clin Parmacol 2008; 65:708-715. (Pubitemid 351535081)
-
(2008)
British Journal of Clinical Pharmacology
, vol.65
, Issue.5
, pp. 708-715
-
-
Wide, K.1
Larsson, H.2
Bertilsson, L.3
Diczfalusy, U.4
-
32
-
-
77949721082
-
Classical twin design in modern pharmacogenomics studies
-
Rahmioglu N, Ahmadi KR. Classical twin design in modern pharmacogenomics studies. Pharmacogenomics 2010; 11:215-226.
-
(2010)
Pharmacogenomics
, vol.11
, pp. 215-226
-
-
Rahmioglu, N.1
Ahmadi, K.R.2
-
33
-
-
67650602114
-
Relative impact of genotype and enzyme induction on the metabolic capacity of CYP2C9 in healthy volunteers
-
Vormfelde SV, Brockmö ller J, Bauer S, Herchenhein P, Kuon J, Meineke I, et al. Relative impact of genotype and enzyme induction on the metabolic capacity of CYP2C9 in healthy volunteers. Clin Pharmacol Ther 2009; 86:54-61.
-
(2009)
Clin Pharmacol Ther
, vol.86
, pp. 54-61
-
-
Vormfelde, S.V.1
Brockmöller, J.2
Bauer, S.3
Herchenhein, P.4
Kuon, J.5
Meineke, I.6
|