Twenty-first century vaccinomics innovation systems: Capacity building in the global south and the role of Product Development Partnerships (PDPs)

OMICS A Journal of Integrative Biology

Volumn 15, Issue 9, 2011, Pages 539-543

  Huzair, Farah ^a,b   Borda Rodriguez, Alexander ^a   Upton, Mary ^a  

^a OPEN UNIVERSITY   (United Kingdom)

^b ESRC Centre for Economic and Social Research on Innovation in Genomics   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AFRICA; ASIA; BIOMICS; HUMAN; NONHUMAN; PRIORITY JOURNAL; PRODUCT DEVELOPMENT; PUBLIC-PRIVATE PARTNERSHIP; REVIEW; SOUTH AND CENTRAL AMERICA; VACCINE PRODUCTION; VACCINOMICS;

CLINICAL TRIALS AS TOPIC; CONSUMER PARTICIPATION; DELIVERY OF HEALTH CARE; DEVELOPING COUNTRIES; DIFFUSION OF INNOVATION; GENOMICS; HUMANS; INTERNATIONAL COOPERATION; ORGANIZATIONAL INNOVATION; PREVENTIVE MEDICINE; PUBLIC HEALTH ADMINISTRATION; VACCINATION; VACCINES;

EID: 80052769075     PISSN: 15362310     EISSN: 15578100     Source Type: Journal    
DOI: 10.1089/omi.2011.0036     Document Type: Review

References (35)

1. Altenhoff, A.M., Schneider, A., Gonnet, G.H., and Dessimoz, C. (2011). OMA 2011: orthology inference among 1000 complete genomes. Nucleic Acids Res 39, D289-D294.
2. Bagnoli, F., and Rappuoli, R. (2006). Targeting infectious diseases in the genomics era. Curr Opin Investig Drugs 7, 695-698. (Pubitemid 44263172)
3. Brett, E.A. (2000). Understanding organisations and institutions. In Managing Development. D. Robinson, T. Hewitt, and T. Harries, eds. (Sage, London).
4. Burnside, A.C., and Dollar, D. (1997). Aid, Policies and Growth. World Bank Policy Research Working Paper No. 569252.
5. Burris, S., and Davis, C. (2009) Assessing social risks prior to commencement of a clinical trial: due diligence or ethical inflation? Am J Bioeth 9, 48-54.
6. Chataway, J., and Hanlin, R. (2008). Sustainable vaccine development: The International AIDS Vaccine Initiative (IAVI) and capacity building. Innogen Briefing Paper 7. Available at 20(Vaccine)%20Development.pdf
7. Freeman, C. (1987). Technology Policy and Economic Performance (Pinter Publishers, London).
8. Fukuda-Parr, S., Lopes, C., and Malik, K. (2002). Capacity for Development, New Solutions to Old Problems. United Nations Development Program (Earthscan Publications Ltd. London).
9. GAVI Alliance. (2010). Saving lives and protecting health, results and opportunities. Available at www.gavialliance.org/resources/GAVI-Updated-Results- EN-May2010.pdf
10. Gilbert, J.A., Meyer, F., Antonopoulos, D., Balaji, P., Brown, C.T., Brown, C.T., et al. (2010). Meeting report: the terabase metagenomics workshop and the vision of an Earth microbiome project. Stand Genomic Sci 3, 243-248.
11. Grace, C. (2010). Product Development Partnerships (PDPs): Lessons from PDPs established to develop new health technologies for neglected diseases (DFID Human Development Resource Centre). Available at Documents/publications1/hdrc/ lssns-pdps-estb-dev-new-hlthtech- negl-diseases.pdf
12. Hey, T., Tansley, S., and Tolle, K. (2009). The Fourth Paradigm: Data-Intensive Scientific Discovery (Microsoft Research, Redmond, WA).
13. Hotez, P.J., and Pecoul, B. (2010) 'Manifesto' for advancing the control and elimination of neglected tropical diseases. PLoS Negl Trop Dis 4, e718.
14. Jasanoff S. ed; 2006 States of Knowledge: The Co-Production of Science and Social Order. London Routledge
15. Kennedy, R.B., and Poland, G.A. (2010). The identification of HLA class II-restricted T cell epitopes to vaccinia virus membrane proteins. Virology 408, 232-240.
16. Keusch, G.T., Kilama,W.L., Moon, S., Szlezak, N.A., and Michaud, C.M. (2010). The global health system linking knowledge with action-learning from malaria. PLoS Med 7, e1000179.
17. Kickbusch, I., Hein, W., and Silberschmidt, G. (2010). Addressing global health governance challenges through a new mechanism: the proposal for a Committee C of the World Health Assembly. J Law Med Ethics 38, 550-563.
18. Kolker, E. (2011). Special issue on data-intensive science. OMICS 15, 197-198.
19. Lesch, A., Kafaar, Z., Kagee, A., and Schwartz, L. (2006). Community members' perceptions of enablers and inhibitors to participation in HIV vaccine trials. S Afr J Psychol, 36, 734-761.
20. Lundvall, B.A. (1992). National Systems of Innovation: Towards a Theory of Innovation and Interactive Learning (Pinter Publishers, London).
21. Marshall, W.E. (2005). Aids, race and the limits of science. Soc Sci Med 60, 2515-2525.
22. Metcalf, C. (1995). The economic foundations of technology policy: equilibrium and evolutionary perspectives. In andbook of the Economics of Innovation and Technological Change. P. Stoneman, ed. (Blackwell Publishers, Oxford).
23. Nattras, N. (2007). Mortal Combat: AIDS Denialism and the Struggle for Antiretrovirals in South Africa (University of Kwazulu-Natal Press, Scottsville).
24. North, D. (1990). Institutions, Institutional Change and Economic Performance (Cambridge University Press, Cambridge).
25. Ozdemir, V. (2009). What to do when the risk environment is rapidly shifting and heterogeneous? Anticipatory governance and real-time assessment of social risks in multiply marginalized populations can prevent IRB mission creep, ethical inflation or underestimation of risks. Am J Bioeth 9, 65-68.
26. Ozdemir, V., Husereau, D., Hyland, S., Samper, S., and Salleh, M.Z. (2009) Personalized medicine beyond genomics: new technologies, global health diplomacy and anticipatory governance. Curr Pharmacogenomics Person Med 7, 225-230.
27. Pang, T., Daulaire, N., Keusch, G., Leke, R., Piot, P., Reddy, S., et al. (2010). The new age of global health governance holds promise. Nat Med 16, 1181.
28. Pizza, M., Scarlato, V., Masignani, V., Giuliani, M.M., Aricǒ, B., Comanducci, M., et al. (2000). Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. Science 287, 1816-1820.
29. Ruger, J.P. (2010). Health and Social Justice (Oxford University Press, Oxford).
30. Scarselli, M., Giuliani, M.M., Adu-Bobie, J., Pizza, M., and Rappuoli, R. (2005). The Impact of genomics on vaccine design. Trends Biotechnol 23, 85-91.
31. Serruto, D., and Rappuoli, R. (2006). Post genomic vaccine development. FEBS Lett 580, 2985-2992.
32. Singer, P.A., and Daar, A.S. (2001). Harnessing genomics and biotechnology to improve global health equity. Science 294, 87-90.
33. UNAIDS: 2010 Report on the Global AIDS Epidemic. Available at http://www.unaids.org/globalreport/Global-report.htm
34. Upton, M.E. (2011 The Politics of Health: Community Engagement in South African HIV Vaccine Clinical Trial Sites (The Open University, Milton Keynes), PhD Thesis.
35. Wilson, G. (2007). Knowledge, innovation and re-inventing technical assistance for development. Prog Dev Stud 7, 183-199.