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Volumn 5, Issue 3, 2011, Pages 209-215

In vitro metabolism of phenstatin: Potential pharmacological consequences

Author keywords

Liver microsomes; Metabolites; Phenstatin; Prostate cancer; Tubilin polymerization

Indexed keywords

ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; CARBONYL REDUCTASE; COMBRETASTATIN A4; COMBRETASTATIN A4 PHOSPHATE; O DEMETHYLASE; PHENSTATIN; UNCLASSIFIED DRUG;

EID: 80052765465     PISSN: 18723128     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231211796904973     Document Type: Article
Times cited : (13)

References (9)
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    • A pinacol rearrangement/ oxidation synthetic route to hydroxyphenstatin
    • Pettit, G.R.; Lippert, J.W.; Herald, D.L. A pinacol rearrangement/ oxidation synthetic route to hydroxyphenstatin. J. Org. Chem., 2000, 65, 7438-7444.
    • (2000) J. Org. Chem. , vol.65 , pp. 7438-7444
    • Pettit, G.R.1    Lippert, J.W.2    Herald, D.L.3
  • 3
    • 4143147349 scopus 로고    scopus 로고
    • Discovering drugs through biological transformation: Role of pharmacologically active metabolites in drug discovery
    • Fura, A.; Shu, Y.Z.; Zhu, M.; Hanson, R.L.; Roongta, V.; Humphreys W.G. Discovering drugs through biological transformation: Role of pharmacologically active metabolites in drug discovery. J. Med. Chem., 2004, 47(18), 4339-4351.
    • (2004) J. Med. Chem. , vol.47 , Issue.18 , pp. 4339-4351
    • Fura, A.1    Shu, Y.Z.2    Zhu, M.3    Hanson, R.L.4    Roongta, V.5    Humphreys, W.G.6
  • 4
    • 0037869224 scopus 로고    scopus 로고
    • Synergistic antiproliferative and apoptotic effects induced by epidermal growth factor receptor and protein kinase A inhibitors in human prostatic cancer cell lines
    • Mimeault, M.; Pommery, N.; Hénichart, J.P. Synergistic antiproliferative and apoptotic effects induced by epidermal growth factor receptor and protein kinase A inhibitors in human prostatic cancer cell lines. Int. J. Cancer, 2003, 106(1), 116-124.
    • (2003) Int. J. Cancer , vol.106 , Issue.1 , pp. 116-124
    • Mimeault, M.1    Pommery, N.2    Hénichart, J.P.3
  • 7
    • 36349000649 scopus 로고    scopus 로고
    • In vitro metabolism study of Combretastatin A-4 in rat and human liver microsomes
    • Aprile, S.; Del Grosso, E.; Tron, G.C.; Grosa, G. In vitro metabolism study of Combretastatin A-4 in rat and human liver microsomes. Drug Metab. Dispos., 2007, 35, 2252-2261.
    • (2007) Drug Metab. Dispos. , vol.35 , pp. 2252-2261
    • Aprile, S.1    del Grosso, E.2    Tron, G.C.3    Grosa, G.4
  • 8
    • 79952513499 scopus 로고    scopus 로고
    • Current and emerging treatment modalities for metastatic castrationresistant prostate cancer
    • Bracarda, S.; Logothetis, C.; Sternberg, C.N.; Oudard, S. Current and emerging treatment modalities for metastatic castrationresistant prostate cancer. BJU Int., 2011, 107, 13-20.
    • (2011) BJU Int. , vol.107 , pp. 13-20
    • Bracarda, S.1    Logothetis, C.2    Sternberg, C.N.3    Oudard, S.4
  • 9
    • 84869220434 scopus 로고    scopus 로고
    • Second-line chemotherapy in metastatic docetaxel-resistant prostate cancer: A review
    • Feb 20. [Epub ahead of print]
    • Colloca, G.; Venturino, A.; Checcaglini, F. Second-line chemotherapy in metastatic docetaxel-resistant prostate cancer: a review. Med. Oncol., 2011 Feb 20. [Epub ahead of print]
    • (2011) Med. Oncol.
    • Colloca, G.1    Venturino, A.2    Checcaglini, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.