Young-onset rectal cancer: Presentation, pattern of care and long-term oncologic outcomes compared to a matched older-onset cohort

Annals of Surgical Oncology

Volumn 18, Issue 9, 2011, Pages 2469-2476

  You, Y Nancy ^a   Dozois, Eric J ^a   Boardman, Lisa A ^a   Aakre, Jeremiah ^a   Huebner, Marianne ^a   Larson, David W ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL;

ADULT; ADVANCED CANCER; AGED; ANUS SPHINCTER; ARTICLE; CANCER PATIENT; CANCER RECURRENCE; CANCER STAGING; COHORT ANALYSIS; DISEASE FREE SURVIVAL; DISTANT METASTASIS; FEMALE; FOLLOW UP; HISTOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PATIENT CARE; RECTUM CANCER; TREATMENT OUTCOME;

ADENOCARCINOMA; ADENOCARCINOMA, MUCINOUS; ADOLESCENT; ADULT; AGE FACTORS; AGE OF ONSET; AGED; CARCINOMA, SIGNET RING CELL; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PHYSICIAN'S PRACTICE PATTERNS; PROSPECTIVE STUDIES; RECTAL NEOPLASMS; SURVIVAL RATE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 80052756922     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-011-1674-7     Document Type: Article

References (31)

1. Cancer Facts & Figures 2010. American Cancer Society. www.cancer.org. Accessed July 1, 2010.
2. BK Edwards E Ward BA Kohler, et al. 2010 Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates Cancer. 116 544 573 19998273 10.1002/cncr.24760
3. RL Siegel A Jemal EM Ward 2009 Increase in incidence of colorectal cancer among young men and women in the United States Cancer Epidemiol Biomarkers Prev. 18 1695 1698 19505901 10.1158/1055-9965.EPI-09-0186
4. BH Endreseth P Romundstad HE Myrvold, et al. 2006 Rectal cancer in the young patient Dis Colon Rectum. 49 993 1001 16741599 10.1007/s10350-006-0558-6 (Pubitemid 44060853)
5. LA Boardman RA Johnson GM Petersen, et al. 2007 Higher frequency of diploidy in young-onset microsatellite-stable colorectal cancer Clin Cancer Res. 13 2323 2328 17438090 10.1158/1078-0432.CCR-06-2739 1:CAS:528: DC%2BD2sXkt1enurw%3D (Pubitemid 46698580)
6. E Fernebro B Halvarsson B Baldetorp, et al. 2002 Predominance of CIN versus MSI in the development of rectal cancer at young age BMC Cancer. 2 25 12379157 10.1186/1471-2407-2-25 (Pubitemid 38851296)
7. M Nilbert M Planck E Fernebro, et al. 1999 Microsatellite instability is rare in rectal carcinomas and signifies hereditary cancer Eur J Cancer. 35 942 945 10533476 10.1016/S0959-8049(99)00045-3 1:CAS:528:DyaK1MXktlSjsb8%3D (Pubitemid 29277129)
8. LA Boardman S Schmidt NM Lindor, et al. 2001 A search for germline APC mutations in early onset colorectal cancer or familial colorectal cancer with normal DNA mismatch repair Genes Chromosomes Cancer. 30 181 186 11135435 10.1002/1098-2264(2000)9999:9999<::AID-GCC1074>3.0.CO;2-K 1:CAS:528:DC%2BD3MXnsFyhtA%3D%3D (Pubitemid 32044599)
9. DL Riegert-Johnson RA Johnson KG Rabe, et al. 2007 The value of MUTYH testing in patients with early onset microsatellite stable colorectal cancer referred for hereditary nonpolyposis colon cancer syndrome testing Genet Test. 11 361 365 18294051 10.1089/gte.2007.0014 1:CAS:528:DC%2BD1cXmt1yrsw%3D%3D
10. EJ Dozois LA Boardman W Suwanthanma, et al. 2008 Young-onset colorectal cancer in patients with no known genetic predisposition: can we increase early recognition and improve outcome? Medicine (Balt) 87 259 263 10.1097/MD. 0b013e3181881354
11. JB O'Connell MA Maggard EH Livingston, et al. 2004 Colorectal cancer in the young Am J Surg. 187 343 348 15006562 10.1016/j.amjsurg.2003.12.020 (Pubitemid 38299499)
12. JB O'Connell MA Maggard JH Liu, et al. 2004 Are survival rates different for young and older patients with rectal cancer? Dis Colon Rectum. 47 2064 2069 15657655 10.1007/s10350-004-0738-1 (Pubitemid 40179066)
13. WH Isbister J Fraser 1990 Large-bowel cancer in the young: a national survival study Dis Colon Rectum. 33 363 366 2328623 10.1007/BF02156258 1:STN:280:DyaK3c3ivVSqtg%3D%3D (Pubitemid 20169150)
14. DC McMillan CS McArdle 2009 The impact of young age on cancer-specific and non-cancer-related survival after surgery for colorectal cancer: 10-year follow-up Br J Cancer. 101 557 560 19672260 10.1038/sj.bjc.6605222 1:STN:280:DC%2BD1MrkvFGqtw%3D%3D
15. PM Griffin JM Liff RS Greenberg, et al. 1991 Adenocarcinomas of the colon and rectum in persons under 40 years old. A population-based study Gastroenterology. 100 1033 1040 2001800 1:STN:280:DyaK3M7mtVyrtw%3D%3D
16. SD Heys TJ O'Hanrahan J Brittenden, et al. 1994 Colorectal cancer in young patients: a review of the literature Eur J Surg Oncol. 20 225 231 8181597 1:STN:280:DyaK2c3jsleitQ%3D%3D (Pubitemid 24166370)
17. PY Lee WS Fletcher ES Sullivan, et al. 1994 Colorectal cancer in young patients: characteristics and outcome Am Surg. 60 607 612 8030817 1:STN:280:DyaK2czgtlyltA%3D%3D (Pubitemid 24229420)
18. JB O'Connell MA Maggard JH Liu, et al. 2003 Rates of colon and rectal cancers are increasing in young adults Am Surg. 69 866 872 14570365
19. Bleyer A, O'Leary M, Barr R, et al. Cancer epidemiology in older adolescents and young adults 15 to 29 years of age, including SEER incidence and survival: 1975-2000. Vol. NIH Pub. No. 06-5767: National Cancer Institute, 2006.
20. S Bulow 1980 Colorectal cancer in patients less than 40 years of age in Denmark, 1943-1967 Dis Colon Rectum. 23 327 336 7398507 10.1007/BF02586840 1:STN:280:DyaL3c3ksFKhtw%3D%3D (Pubitemid 10056080)
21. E Mitry AM Benhamiche JL Jouve, et al. 2001 Colorectal adenocarcinoma in patients under 45 years of age: comparison with older patients in a well-defined French population Dis Colon Rectum. 44 380 387 11289284 10.1007/BF02234737 1:STN:280:DC%2BD3M7pvFyrtg%3D%3D (Pubitemid 32226327)
22. J Nath C Wigley MR Keighley, et al. 2009 Rectal cancer in young adults: a series of 102 patients at a tertiary care centre in India Colorectal Dis. 11 475 479 18616736 10.1111/j.1463-1318.2008.01607.x 1:STN:280: DC%2BD1MvhsFSqsw%3D%3D
23. I Sultan C Rodriguez-Galindo H El-Taani, et al. 2010 Distinct features of colorectal cancer in children and adolescents: a population-based study of 159 cases Cancer. 116 758 765 19957323 10.1002/cncr.24777
24. B Levin DA Lieberman B McFarland, et al. 2008 Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology Gastroenterology. 134 1570 1595 18384785 10.1053/j.gastro.2008.02.002 1:CAS:528:DC%2BD1cXntVWgs74%3D (Pubitemid 351615355)
25. U.S. Preventive Services Task Force. Screening for colorectal cancer: U.S. Preventive Services Task Force Recommendation Statement. AHRS Publication 08-05124-EF-3, October 2008. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/uspstf08/colocancer/colors.htm.
26. HM Quah R Joseph D Schrag, et al. 2007 Young age influences treatment but not outcome of colon cancer Ann Surg Oncol. 14 2759 2765 17593332 10.1245/s10434-007-9465-x 1:STN:280:DC%2BD2srmtVCmsA%3D%3D (Pubitemid 47460634)
27. R Gryfe H Kim ET Hsieh, et al. 2000 Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer N Engl J Med. 342 69 77 10631274 10.1056/NEJM200001133420201 1:STN:280:DC%2BD3c%2FotVeitA%3D%3D (Pubitemid 30036597)
28. A Umar CR Boland JP Terdiman, et al. 2004 Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability J Natl Cancer Inst. 96 261 268 14970275 10.1093/jnci/djh034 1:CAS:528:DC%2BD2cXhsV2qtLk%3D (Pubitemid 38256271)
29. WS Samowitz K Curtin RK Wolff, et al. 2009 Microsatellite instability and survival in rectal cancer Cancer Causes Control. 20 1763 1768 19669908 10.1007/s10552-009-9410-3
30. CM Ribic DJ Sargent MJ Moore, et al. 2003 Tumor microsatellite- instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer N Engl J Med. 349 247 257 12867608 10.1056/NEJMoa022289 1:CAS:528:DC%2BD3sXlsVGjsbY%3D (Pubitemid 36859476)
31. R Jover P Zapater A Castells, et al. 2009 The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status Eur J Cancer. 45 365 373 18722765 10.1016/j.ejca.2008.07.016 1:CAS:528:DC%2BD1MXhs1CnsLo%3D