Programmed cell death 4 (Pdcd4) expression in colorectal adenocarcinoma: Association with clinical stage

Oncology Letters

Volumn 2, Issue 6, 2011, Pages 1053-1057

  Lim, Sung Chul ^a   Hong, Ran ^a  

^a Chosun University   (South Korea)

Author keywords

Colorectal adenocarcinoma; Programmed cell death 4

Indexed keywords

PDCD4 PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER STAGING; CELL NUCLEUS; COLORECTAL CARCINOMA; CYTOPLASM; DISEASE FREE INTERVAL; FEMALE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PROGNOSIS; PROTEIN EXPRESSION; TUMOR GROWTH;

EID: 80052732910     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2011.365     Document Type: Article

References (23)

1. Jansen AP, Camalier CE and Colburn NH: Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis. Cancer Res 65: 6034-6041, 2005.
2. Hilliard A, Hilliard B, Zheng SJ, et al: Translational regulation of autoimmune inflammation and lymphoma genesis by programmed cell death 4. J Immunol 177: 8095-8102, 2006.
3. Yang HS, Matthews CP, Clair T, et al: Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion. Mol Cell Biol 26: 1297-1306, 2006.
4. Soejima H, Miyoshi O, Yoshinaga H, et al: Assignment of the programmed cell death 4 gene (Pdcd4) to human chromosome band 10q24 by in situ hybridization. Cytogenet Cell Genet 87: 113-114, 1999.
5. Cmarik JL, Min H, Hegamyer G, et al: Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. Proc Natl Acad Sci USA 96: 14037-14042, 1999.
6. Bitomsky N, Bohm M and Klempnauer KH: Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun. Oncogene 23: 7484-7493, 2004.
7. Goke R, Barth P, Schmidt A, Samans B and Lankat-Buttgereit B: Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21(Waf1/Cip1). Am J Physiol Cell Physiol 287: 1541-1546, 2004.
8. Leupold JH, Yang HS, Colburn NH, Asangani I, Post S and Allgayer H: Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors. Oncogene 26: 4550-4562, 2007.
9. Yang HS, Jansen AP, Nair R, et al: A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-κB or ODC transactivation. Oncogene 20: 669-676, 2001.
10. Yang HS, Knies JL, Stark C and Colburn NH: Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation. Oncogene 22: 3712-3720, 2003.
11. Li T, Li D, Sha J, Sun P and Huang Y: MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. Biochem Biophys Res Commun 383: 280-285, 2001.
12. Wen YH, Shi X, Chiriboga L, Matsahashi S, Yee H and Afonja O: Alterations in the expression of Pdcd4 in ductal carcinoma of the breast. Oncol Rep 18: 1387-1393, 2007.
13. Wei NA, Liu SS, Leung TH, et al: Loss of Programmed cell death 4 (Pdcd4) associates with the progression of ovarian cancer. Mol Cancer 8: 70, 2009.
14. Bohm M, Sawicka K, Siebrasse JP, Brehmer-Fastnacht A, Peters R and Klempnauer KH: The transformation suppressor protein Pdcd4 shuttles between nucleus and cytoplasm and binds RNA. Oncogene 22: 1905-1910, 2003.
15. Lankat-Buttgereit B, Gregel C, Knolle A, Hasilik A, Arnold R and Goke R: Pdcd4 inhibits growth of tumor cells by suppression of carbonic anhydrase type II. Mol Cell Endocrinol 214: 149-153, 2004.
16. Park JK, Hong R, Kim KJ, Lee TB and Lim SC: Significance of p-STAT3 expression in human colorectal adenocarcinoma. Oncol Rep 20: 597-604, 2008.
17. Greene FL, Page DL, Fleming ID, et al (eds.): AJCC Cancer Staging Manual. 6th edition. Springer-Verlag, New York, pp157-164, 2002.
18. Mudduluru G, Medved F, Grobholz R, et al: Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer. Cancer 110: 1697-1707, 2007.
19. Yang HS, Jansen AP, Komar AA, et al: The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Mol Cell Biol 23: 26-37, 2003.
20. Chen Y, Knosel T, Kristiansen G, et al: Loss of Pdcd4 expression in human lung cancer correlates with tumour progression and prognosis. J Pathol 200: 640-646, 2003.
21. Yoshinaga H, Matsuhashi S, Fujiyama C and Masaki Z: Novel human Pdcd4 (H731) gene expressed in proliferative cells is expressed in the small duct epithelial cells of the breast as revealed by an anti-H731 antibody. Pathol Int 49: 1067-1077, 1999.
22. Palamarchuk A, Efanov A, Maximov V, Aqeilan RI, Croce CM and Pekarsky Y: Akt phosphorylates and regulates Pdcd4 tumor suppressor protein. Cancer Res 65: 11282-11286, 2005.
23. Zhang H, Ozaki I, Mizuta T, et al: Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma. Oncogene 25: 6101-6112, 2005.