메뉴 건너뛰기




Volumn 18, Issue 5, 2011, Pages 418-425

Human Male infertility: A Complex Multifactorial Phenotype

Author keywords

azoospermia; epigenetics; HPG axis; MicroRNA; multifactorial

Indexed keywords

ANIMAL; EPIGENETICS; GENETICS; HUMAN; MALE; MALE INFERTILITY; METHODOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; PHYSIOLOGY; REVIEW; SPERMATOGENESIS; SPERMATOZOON;

EID: 80052730921     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719111398148     Document Type: Review
Times cited : (70)

References (68)
  • 1
    • 0036798824 scopus 로고    scopus 로고
    • Genetic dissection of mammalian fertility pathways
    • Matzuk M.M. Lamb D.J. Genetic dissection of mammalian fertility pathways. Nature Cell Biol Nature Med. 2002; 8 (suppl): S41 - S49.
    • (2002) Nature Cell Biol Nature Med , vol.8 , pp. S41-S49
    • Matzuk, M.M.1    Lamb, D.J.2
  • 2
    • 0035665312 scopus 로고    scopus 로고
    • Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with the other techniques
    • Evenson D.P. Larson K.L. Jost L.K. Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with the other techniques. J Androl. 2002; 23 (1): 25 - 43.
    • (2002) J Androl , vol.23 , Issue.1 , pp. 25-43
    • Evenson, D.P.1    Larson, K.L.2    Jost, L.K.3
  • 3
    • 0028933276 scopus 로고
    • Mammalian sperm DNA susceptibility to in-situ denaturation associated with the presence of DNA strand breaks as measured by the terminal deoxynucleotidyltransferase assay
    • Sailer B.L. Jost L.K. Evenson D.P. Mammalian sperm DNA susceptibility to in-situ denaturation associated with the presence of DNA strand breaks as measured by the terminal deoxynucleotidyltransferase assay. J Androl. 1995; 16 (1): 80 - 87.
    • (1995) J Androl , vol.16 , Issue.1 , pp. 80-87
    • Sailer, B.L.1    Jost, L.K.2    Evenson, D.P.3
  • 4
    • 0025922098 scopus 로고
    • Cytogenetic studies in male infertility: a review
    • De Brakeleer M. Dao T.N. Cytogenetic studies in male infertility: a review. Hum Reprod. 1991; 6 (2): 245 - 250.
    • (1991) Hum Reprod , vol.6 , Issue.2 , pp. 245-250
    • De Brakeleer, M.1    Dao, T.N.2
  • 5
    • 0141813754 scopus 로고    scopus 로고
    • Idiopathic cases of male infertility from a region in India show low incidence of Y-chromosome microdeletion
    • Ambasudhan R. Singh K. Agrawal J.K. et al. Idiopathic cases of male infertility from a region in India show low incidence of Y-chromosome microdeletion. J Biosci. 2003; 28 (5): 605 - 612.
    • (2003) J Biosci , vol.28 , Issue.5 , pp. 605-612
    • Ambasudhan, R.1    Singh, K.2    Agrawal3
  • 6
    • 24044476597 scopus 로고    scopus 로고
    • Chromosomal studies in infertile men with oligozoospermia & non-obstructive azoospermia
    • Nagvenkar P. Desai K. Hinduja I. Zaveri K. Chromosomal studies in infertile men with oligozoospermia & non-obstructive azoospermia. Indian J Med Res. 2005; 122 (1): 34 - 42.
    • (2005) Indian J Med Res , vol.122 , Issue.1 , pp. 34-42
    • Nagvenkar, P.1    Desai, K.2    Hinduja, I.3    Zaveri, K.4
  • 7
    • 0043167788 scopus 로고    scopus 로고
    • Nuclear and mitochondrial DNA analysis of a 2,000-year-old necropolis in the Egyin Gol Valley of Mongolia
    • Keyser-Tracqui C. Crubézy E. Ludes B. Nuclear and mitochondrial DNA analysis of a 2,000-year-old necropolis in the Egyin Gol Valley of Mongolia. Am J Hum Genet. 2003; 73 (2): 247 - 260.
    • (2003) Am J Hum Genet , vol.73 , Issue.2 , pp. 247-260
    • Keyser-Tracqui, C.1    Crubézy, E.2    Ludes, B.3
  • 8
    • 0028304516 scopus 로고
    • Familial pericentric inversion of chromosome 1 (p34q23) and male infertility with stage specific spermatogenic arrest
    • Meschede D. Froster U.G. Bergmann M. Nieschlag E. Familial pericentric inversion of chromosome 1 (p34q23) and male infertility with stage specific spermatogenic arrest. J Med Genet. 1994; 31 (7): 573 - 575.
    • (1994) J Med Genet , vol.31 , Issue.7 , pp. 573-575
    • Meschede, D.1    Froster, U.G.2    Bergmann, M.3    Nieschlag, E.4
  • 9
    • 84997952198 scopus 로고    scopus 로고
    • Genetic risks of intracytoplasmic sperm injection in the treatment of male infertility: recommendations for genetic counseling and screening
    • Jhonson M.D. Genetic risks of intracytoplasmic sperm injection in the treatment of male infertility: recommendations for genetic counseling and screening. Fert Steril. 1998; 70 (3): 119 - 124.
    • (1998) Fert Steril , vol.70 , Issue.3 , pp. 119-124
    • Jhonson, M.D.1
  • 10
    • 0037967242 scopus 로고    scopus 로고
    • The male specific region of the human Y chromosome is a mosaic of discrete sequence classes
    • Skaletsky H. Kuroda-Kawaguchi T. Patrick J.M. et al. The male specific region of the human Y chromosome is a mosaic of discrete sequence classes. Nature. 2003; 423 (6942): 825 - 837.
    • (2003) Nature , vol.423 , Issue.6942 , pp. 825-837
    • Skaletsky, H.1    Kuroda-Kawaguchi, T.2    Patrick3
  • 11
    • 0035865360 scopus 로고    scopus 로고
    • A physical map of the human Y chromosome
    • Tilford C.A. Kuroda-Kawaguchi T. Skaletsky H. et al. A physical map of the human Y chromosome. Nature. 2001; 409 (6822): 943 - 945.
    • (2001) Nature , vol.409 , Issue.6822 , pp. 943-945
    • Tilford, C.A.1    Kuroda-Kawaguchi, T.2    Skaletsky3
  • 12
    • 0344588222 scopus 로고    scopus 로고
    • Genetic disorders of human spermatogenesis
    • In: Geffery M.H. Wailes, eds. Proceedings of 6th International Congress of andrology, Austria
    • Vogt P.H. Genetic disorders of human spermatogenesis. In: Geffery M.H. Wailes, eds. Current advances in Andrology. Proceedings of 6th International Congress of andrology, Austria, 1997; 51 - 75.
    • (1997) , pp. 51-75
    • Vogt, P.H.1
  • 13
    • 0035184973 scopus 로고    scopus 로고
    • The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men
    • Kuroda-Kawaguchi T. Skaletsky H. Brown L.G. et al. The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men. Nat Genet. 2001; 29 (3): 279 - 286.
    • (2001) Nat Genet , vol.29 , Issue.3 , pp. 279-286
    • Kuroda-Kawaguchi, T.1    Skaletsky, H.2    Brown3
  • 14
    • 0032796205 scopus 로고    scopus 로고
    • Screening for microdeletion of Y chromosome genes in patients undergoing intracytoplasmic sperm injection
    • Krausz C. Bussani-Mastellone C. Granchi S. McElreavey K. Scaselli G. Forti G. Screening for microdeletion of Y chromosome genes in patients undergoing intracytoplasmic sperm injection. Hum Reprod. 1999; 14 (7): 1717 - 1721.
    • (1999) Hum Reprod , vol.14 , Issue.7 , pp. 1717-1721
    • Krausz, C.1    Bussani-Mastellone, C.2    Granchi, S.3    McElreavey, K.4    Scaselli, G.5    Forti, G.6
  • 16
    • 0037438451 scopus 로고    scopus 로고
    • Lack of association between Y chromosome haplogroups and male infertility
    • Carvalho C.M.B. Fujisawa M. Shirakawa T. et al. Lack of association between Y chromosome haplogroups and male infertility. Am J Med Genet. 2003; 116A (2): 152 - 158.
    • (2003) Am J Med Genet , vol.116A , Issue.2 , pp. 152-158
    • Carvalho, C.M.B.1    Fujisawa, M.2    Shirakawa3
  • 17
    • 67649114103 scopus 로고    scopus 로고
    • Y-haplotypes and idiopathic male infertility in an Indian population
    • Singh K. Raman R. Y-haplotypes and idiopathic male infertility in an Indian population. Indian J Hum Genet. 2009; 15 (1): 19 - 22.
    • (2009) Indian J Hum Genet , vol.15 , Issue.1 , pp. 19-22
    • Singh, K.1    Raman, R.2
  • 19
    • 0034969838 scopus 로고    scopus 로고
    • Aneuploidy rate in spermatozoa of selected men with abnormal semen parameters
    • Calogero A.E. Palma A.D. Grazioso C. et al. Aneuploidy rate in spermatozoa of selected men with abnormal semen parameters. Hum Reproduc. 2001; 16 (6): 1172 - 1179.
    • (2001) Hum Reproduc , vol.16 , Issue.6 , pp. 1172-1179
    • Calogero, A.E.1    Palma, A.D.2    Grazioso3
  • 20
    • 26844470927 scopus 로고    scopus 로고
    • The phenotype of short stature homeobox gene (SHOX) deficiency in childhood: contrasting children with Leri-Weill dyschondrosteosis and Turner syndrome
    • Ross J.L. Kowal K. Quigley C.A. et al. The phenotype of short stature homeobox gene (SHOX) deficiency in childhood: contrasting children with Leri-Weill dyschondrosteosis and Turner syndrome. J Pediatr. 2005; 147 (4): 499 - 507.
    • (2005) J Pediatr , vol.147 , Issue.4 , pp. 499-507
    • Ross, J.L.1    Kowal, K.2    Quigley3
  • 21
    • 0141506898 scopus 로고    scopus 로고
    • A unification of mosaic structures in the human genome
    • Lercher M.J. Urrutia A.O. Pavlíek A. Hurst L.D. A unification of mosaic structures in the human genome. Hum Mol Genet. 2003; 12 (19): 2411 - 2415.
    • (2003) Hum Mol Genet , vol.12 , Issue.19 , pp. 2411-2415
    • Lercher, M.J.1    Urrutia, A.O.2    Pavlíek, A.3    Hurst, L.D.4
  • 22
    • 0033592186 scopus 로고    scopus 로고
    • Linkage between male infertility and trinucleotide repeat expansion in the androgen-receptor gene
    • Dowsing A.T. Yong E.L. Clark M. McLachlan R.I. Krester D.M. Trounson A.O. Linkage between male infertility and trinucleotide repeat expansion in the androgen-receptor gene. Lancet. 1999; 354 (9179): 640 - 644.
    • (1999) Lancet , vol.354 , Issue.9179 , pp. 640-644
    • Dowsing, A.T.1    Yong, E.L.2    Clark, M.3    McLachlan, R.I.4    Krester, D.M.5    Trounson, A.O.6
  • 23
    • 35948969182 scopus 로고    scopus 로고
    • Male infertility and variation in CAG repeat length in the androgen receptor gene: a meta-analysis
    • Davis-Dao C.A. Tuazon E.D. Sokol R.Z. Cortessis V.K. Male infertility and variation in CAG repeat length in the androgen receptor gene: a meta-analysis. J Clin Endocrinol Metab. 2007; 92 (11): 4319 - 4326.
    • (2007) J Clin Endocrinol Metab , vol.92 , Issue.11 , pp. 4319-4326
    • Davis-Dao, C.A.1    Tuazon, E.D.2    Sokol, R.Z.3    Cortessis, V.K.4
  • 24
    • 0242664116 scopus 로고    scopus 로고
    • Sox3 is required for gonadal function, but not sex determination, in males and females
    • Weiss J. Meeks J.J. Hurley L. Raverot G. Frassetto A. Jameson J.L. Sox3 is required for gonadal function, but not sex determination, in males and females. Mol Cell Biol. 2003; 23 (22): 8084 - 8091.
    • (2003) Mol Cell Biol , vol.23 , Issue.22 , pp. 8084-8091
    • Weiss, J.1    Meeks, J.J.2    Hurley, L.3    Raverot, G.4    Frassetto, A.5    Jameson, J.L.6
  • 26
    • 4043092052 scopus 로고    scopus 로고
    • EAA/EMQN best practice guidelines for molecular diagnosis of Y-chromosomal microdeletions. State of the art 2004
    • Simoni M. Bakker E. Krausz C. EAA/EMQN best practice guidelines for molecular diagnosis of Y-chromosomal microdeletions. State of the art 2004. Int J Androl. 2004; 27 (4): 240 - 249.
    • (2004) Int J Androl , vol.27 , Issue.4 , pp. 240-249
    • Simoni, M.1    Bakker, E.2    Krausz, C.3
  • 27
    • 12244292692 scopus 로고    scopus 로고
    • Genetic abnormalities among severely oligospermic men who are candidates for intracytoplasmic sperm injection
    • Foresta C. Garolla A. Bartoloni L. Bettella A. Ferlin A. Genetic abnormalities among severely oligospermic men who are candidates for intracytoplasmic sperm injection. J Clin Endocrinol Metab. 2005; 90 (1): 152 - 156.
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.1 , pp. 152-156
    • Foresta, C.1    Garolla, A.2    Bartoloni, L.3    Bettella, A.4    Ferlin, A.5
  • 28
    • 0030292382 scopus 로고    scopus 로고
    • The DAZ gene cluster on the human Y chromosome arose from autosomal gene that was transposed, repeatedly amplified and pruned
    • Saxena R. Brown L.G. Hawkins T. et al. The DAZ gene cluster on the human Y chromosome arose from autosomal gene that was transposed, repeatedly amplified and pruned. Nat Genet. 1996; 14 (3): 292 - 299.
    • (1996) Nat Genet , vol.14 , Issue.3 , pp. 292-299
    • Saxena, R.1    Brown, L.G.2    Hawkins3
  • 29
    • 0035185070 scopus 로고    scopus 로고
    • Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility
    • Rovio A.T. Marchington D.R. Donat S. et al. Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility. Nat Genet. 2001; 29 (3): 261 - 262.
    • (2001) Nat Genet , vol.29 , Issue.3 , pp. 261-262
    • Rovio, A.T.1    Marchington, D.R.2    Donat3
  • 30
    • 0025818959 scopus 로고
    • DNA packaging and organization in mammalian spermatozoa: comparison with somatic cells
    • Ward W.S. Coffey D.S. DNA packaging and organization in mammalian spermatozoa: comparison with somatic cells. Biol Reprod. 1991; 44 (4): 569 - 574.
    • (1991) Biol Reprod , vol.44 , Issue.4 , pp. 569-574
    • Ward, W.S.1    Coffey, D.S.2
  • 31
    • 59849126153 scopus 로고    scopus 로고
    • Histone modifications dictate specific biological readouts
    • Munshi A. Shafi G. Aliya N. Histone modifications dictate specific biological readouts. J Genet Genom. 2009; 36 (2): 75 - 88.
    • (2009) J Genet Genom , vol.36 , Issue.2 , pp. 75-88
    • Munshi, A.1    Shafi, G.2    Aliya, N.3
  • 32
    • 0033956680 scopus 로고    scopus 로고
    • An unusual form of purifying selection in sperm protein
    • Rooney A.P. Zhang J. Nei M. An unusual form of purifying selection in sperm protein. Mol Biol Evol. 2000; 17 (2): 278 - 283.
    • (2000) Mol Biol Evol , vol.17 , Issue.2 , pp. 278-283
    • Rooney, A.P.1    Zhang, J.2    Nei, M.3
  • 34
    • 67651037122 scopus 로고    scopus 로고
    • Hydrodynamic propulsion of human sperm
    • Gillies E.A. Cannon R.M. Green R.B. et al. Hydrodynamic propulsion of human sperm. J Fluid Mech. 2009; 625: 445 - 474.
    • (2009) J Fluid Mech , vol.625 , pp. 445-474
    • Gillies, E.A.1    Cannon, R.M.2    Green3
  • 35
    • 26944466235 scopus 로고    scopus 로고
    • DNA integrity is compromised in protamine-deficient human sperm
    • Aoki V.W. Moskovtsev S.I. Willis J. et al. DNA integrity is compromised in protamine-deficient human sperm. J Androl. 2005; 26: 741 - 748.
    • (2005) J Androl , vol.26 , pp. 741-748
    • Aoki, V.W.1    Moskovtsev, S.I.2    Willis3
  • 36
    • 0026059176 scopus 로고
    • Use of aniline blue to assess chromatin condensation in morphologically normal spermatozoa in normal and infertile men
    • Hofman N. Hilscher B. Use of aniline blue to assess chromatin condensation in morphologically normal spermatozoa in normal and infertile men. Hum Reprod. 1991; 6 (7): 979 - 982.
    • (1991) Hum Reprod , vol.6 , Issue.7 , pp. 979-982
    • Hofman, N.1    Hilscher, B.2
  • 39
    • 0029694433 scopus 로고    scopus 로고
    • The gene responsible for adrenal hypoplasia congenita, DAX-1, encodes a nuclear hormone receptor that defines a new class within the superfamily
    • Burris T.P. Guo W. McCabe E.R. The gene responsible for adrenal hypoplasia congenita, DAX-1, encodes a nuclear hormone receptor that defines a new class within the superfamily. Recent Prog Horm Res. 1996; 51: 241 - 259.
    • (1996) Recent Prog Horm Res , vol.51 , pp. 241-259
    • Burris, T.P.1    Guo, W.2    McCabe, E.R.3
  • 40
    • 0017188025 scopus 로고
    • A case of male pseudohermaphroditism associated with elevated LH, normal FSH and low testosterone possibly due to the secretion of an abnormal LH molecule
    • Park I.J. Burnett L.S. Jones H.W. Jr. Migeon C.J. Blizzard R.M. A case of male pseudohermaphroditism associated with elevated LH, normal FSH and low testosterone possibly due to the secretion of an abnormal LH molecule. Acta Endocrinol (Copenh). 1976; 83 (1): 173 - 181.
    • (1976) Acta Endocrinol (Copenh) , vol.83 , Issue.1 , pp. 173-181
    • Park, I.J.1    Burnett, L.S.2    Jones, H.W.3    Migeon, C.J.4    Blizzard, R.M.5
  • 41
    • 0026335545 scopus 로고
    • Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone
    • Weiss J. Axelrod L. Whitcomb R.W. et al. Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone. N Engl J Med. 1992; 326 (3): 179 - 183.
    • (1992) N Engl J Med , vol.326 , Issue.3 , pp. 179-183
    • Weiss, J.1    Axelrod, L.2    Whitcomb3
  • 42
    • 0001192315 scopus 로고
    • Disorders of sexual differentiation
    • Griffin J.E. Wilson J.D. Disorders of sexual differentiation. Campwell’s Urol. 1992; 2: 1509 - 1542.
    • (1992) Campwell’s Urol , vol.2 , pp. 1509-1542
    • Griffin, J.E.1    Wilson, J.D.2
  • 43
    • 0033064556 scopus 로고    scopus 로고
    • Role of heat shock protein HSP70-2 in spermatogenesis
    • Eddy E.M. Role of heat shock protein HSP70-2 in spermatogenesis. Rev Reprod. 1999; 4 (1): 23 - 30.
    • (1999) Rev Reprod , vol.4 , Issue.1 , pp. 23-30
    • Eddy, E.M.1
  • 44
    • 0028143234 scopus 로고
    • Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man
    • Smith E.P. Boyd J. Frank G.R. et al. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med. 1995; 331 (16): 1056 - 1061.
    • (1995) N Engl J Med , vol.331 , Issue.16 , pp. 1056-1061
    • Smith, E.P.1    Boyd, J.2    Frank3
  • 45
    • 67651162120 scopus 로고    scopus 로고
    • Estrogen receptor β gene mutations in Indian infertile men
    • Khattri A. Pandey R.K. Gupta N.J. et al. Estrogen receptor β gene mutations in Indian infertile men. Mol Hum Reproduc. 2009; 15 (8): 513 - 520.
    • (2009) Mol Hum Reproduc , vol.15 , Issue.8 , pp. 513-520
    • Khattri, A.1    Pandey, R.K.2    Gupta3
  • 46
    • 0001887902 scopus 로고
    • Early sexual growth and activity
    • In: Philadelphia, PA WB Saunders Co.
    • Kinsey A.C. Pomeroy W.B. Martin C.E. Early sexual growth and activity. In: Sexual Behavior in the Human Male. Philadelphia, PA: WB Saunders Co., 1948; 157 - 192
    • (1948) , pp. 157-192
    • Kinsey, A.C.1    Pomeroy, W.B.2    Martin, C.E.3
  • 47
    • 0028036288 scopus 로고
    • Inhibition of gonadotropin hormone-releasing hormone release by prolactin from GT1 neuronal cell lines through prolactin receptors
    • Milenkovic L.D. Angelo G. Kelly P.A. Weiner R.I. Inhibition of gonadotropin hormone-releasing hormone release by prolactin from GT1 neuronal cell lines through prolactin receptors. Proc Natl Acad Sci USA. 1994; 91 (4): 1244 - 1247.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.4 , pp. 1244-1247
    • Milenkovic, L.D.1    Angelo, G.2    Kelly, P.A.3    Weiner, R.I.4
  • 48
    • 84998028688 scopus 로고
    • Prolactin-induced modification of testosterone metabolism in man
    • Margrini G. Pallaton M. Felber J.P. Prolactin-induced modification of testosterone metabolism in man. Acta Endocrinol. 1977; 85 (suppl 212): 143.
    • (1977) Acta Endocrinol , vol.85 , pp. 143
    • Margrini, G.1    Pallaton, M.2    Felber, J.P.3
  • 49
    • 0028904997 scopus 로고
    • Dihydrotestosterone is the active androgen in the maintenance of nitric oxide mediated penile erection in the rat
    • Lugg J.A. Rajfer J. Gonzalez-Cadavid N.F. Dihydrotestosterone is the active androgen in the maintenance of nitric oxide mediated penile erection in the rat. Endocrinology. 1995; 136 (4): 1495 - 1501.
    • (1995) Endocrinology , vol.136 , Issue.4 , pp. 1495-1501
    • Lugg, J.A.1    Rajfer, J.2    Gonzalez-Cadavid, N.F.3
  • 50
    • 0028036149 scopus 로고
    • Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study
    • Feldman H.A. Goldstein I. Hatzichristou D.G. Krane R.J. McKinlay J.B. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol. 1994; 151 (1): 54 - 61.
    • (1994) J Urol , vol.151 , Issue.1 , pp. 54-61
    • Feldman, H.A.1    Goldstein, I.2    Hatzichristou, D.G.3    Krane, R.J.4    McKinlay, J.B.5
  • 51
    • 0025022323 scopus 로고
    • Nicotine and cotinine inhibit steroidogenesis in mouse Leydig cells
    • Patterson T.R. Stringham J.D. Meikle A.W. Nicotine and cotinine inhibit steroidogenesis in mouse Leydig cells. Life Sci. 1990; 46 (4): 265 - 272.
    • (1990) Life Sci , vol.46 , Issue.4 , pp. 265-272
    • Patterson, T.R.1    Stringham, J.D.2    Meikle, A.W.3
  • 54
    • 84998091063 scopus 로고    scopus 로고
    • Premature ejaculation: definition, assessment and management
    • Martin J.S. Premature ejaculation: definition, assessment and management. Trend Urol Gynaecol Sex Health. 2010; 15 (3): 39 - 43.
    • (2010) Trend Urol Gynaecol Sex Health , vol.15 , Issue.3 , pp. 39-43
    • Martin, J.S.1
  • 55
    • 32244433720 scopus 로고    scopus 로고
    • Seminiferous cord formation and germ-cell programming: epigenetic transgenerational actions of endocrine disruptors
    • Skinner M. Anway M. Seminiferous cord formation and germ-cell programming: epigenetic transgenerational actions of endocrine disruptors. Ann N Y Acad Sci. 2005; 1061: 18 - 32.
    • (2005) Ann N Y Acad Sci , vol.1061 , pp. 18-32
    • Skinner, M.1    Anway, M.2
  • 56
    • 0041522560 scopus 로고    scopus 로고
    • Role of sperm chromatin abnormalities and DNA damage in m8ale infertility
    • Agarwal A. Said T.M. Role of sperm chromatin abnormalities and DNA damage in m8ale infertility. Hum Reprod Update. 2003; 9 (4): 331 - 345.
    • (2003) Hum Reprod Update , vol.9 , Issue.4 , pp. 331-345
    • Agarwal, A.1    Said, T.M.2
  • 57
    • 0037418193 scopus 로고    scopus 로고
    • Transgenerational inheritance of epigenetic states at the murine Axin (Fu) allele occurs after maternal and paternal transmission
    • Rakyan V.K. Chong S. Champ M.E. et al. Transgenerational inheritance of epigenetic states at the murine Axin (Fu) allele occurs after maternal and paternal transmission. Proc Natl Acad Sci. U S A. 2003; 100 (5): 2538 - 2543.
    • (2003) Proc Natl Acad Sci , vol.100 , Issue.5 , pp. 2538-2543
    • Rakyan, V.K.1    Chong, S.2    Champ3
  • 59
    • 0035849145 scopus 로고    scopus 로고
    • Homozygous methylenetetrahydrofolate reductase C677T mutation and male infertility
    • Bezold G. Lange M. Peter R.U. Homozygous methylenetetrahydrofolate reductase C677T mutation and male infertility. New Eng J Med. 2001; 44 (15): 1172 - 1173.
    • (2001) New Eng J Med , vol.44 , Issue.15 , pp. 1172-1173
    • Bezold, G.1    Lange, M.2    Peter, R.U.3
  • 60
    • 0242661475 scopus 로고    scopus 로고
    • C677T methylenetetrahydrofolate reductase lymorphism interferes with the effects of folic acid and zinc sulfate on sperm concentration
    • Ebisch I.M.W. Heerde W.L. Thomas CMG van der Put N. Wong W.Y. Steegers-Theunissen R.P.M. C677T methylenetetrahydrofolate reductase lymorphism interferes with the effects of folic acid and zinc sulfate on sperm concentration. Fertl Steril. 2003; 80 (5): 1190 - 1194.
    • (2003) Fertl Steril , vol.80 , Issue.5 , pp. 1190-1194
    • Ebisch, I.M.W.1    Heerde, W.L.2    Thomas, C.M.G.3    van der Put, N.4    Wong, W.Y.5    Steegers-Theunissen, R.P.M.6
  • 61
    • 16244371735 scopus 로고    scopus 로고
    • Mutation C677T in the methylenetetrahydrofolate reductase gene is associated with male infertility in an Indian population
    • Singh K. Singh S.K. Sah R. Singh I. Raman R. Mutation C677T in the methylenetetrahydrofolate reductase gene is associated with male infertility in an Indian population. Int J Androl. 2005; 28 (2): 115 - 119.
    • (2005) Int J Androl , vol.28 , Issue.2 , pp. 115-119
    • Singh, K.1    Singh, S.K.2    Sah, R.3    Singh, I.4    Raman, R.5
  • 62
    • 0035139992 scopus 로고    scopus 로고
    • Low seminal plasma folate concentrations are associated with low sperm density and count in male smokers and nonsmokers
    • Wallock L.M. Tamura T. Mayr C.A. Johnston K.E. Ames B.N. Jacob R.A. Low seminal plasma folate concentrations are associated with low sperm density and count in male smokers and nonsmokers. Fertil Steril. 2001; 75 (2): 252 - 259.
    • (2001) Fertil Steril , vol.75 , Issue.2 , pp. 252-259
    • Wallock, L.M.1    Tamura, T.2    Mayr, C.A.3    Johnston, K.E.4    Ames, B.N.5    Jacob, R.A.6
  • 63
    • 0036180440 scopus 로고    scopus 로고
    • Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial
    • Wong W.Y. Merkus H.M. Thomas C.M. Menkveld R. Zielhuis G.A. Steegers-Theunissen R.P. Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial. Fertil Steril. 2002; 77 (3): 491 - 498.
    • (2002) Fertil Steril , vol.77 , Issue.3 , pp. 491-498
    • Wong, W.Y.1    Merkus, H.M.2    Thomas, C.M.3    Menkveld, R.4    Zielhuis, G.A.5    Steegers-Theunissen, R.P.6
  • 64
    • 85046912622 scopus 로고    scopus 로고
    • Environment, lifestyle and infertility—an inter-generational issue
    • Sharpe R.M. Franks S. Environment, lifestyle and infertility—an inter-generational issue. Nat. Cell Biol. 2002; 4 (suppl): s33 - s40.
    • (2002) Nat. Cell Biol , vol.4 , pp. s33-s40
    • Sharpe, R.M.1    Franks, S.2
  • 66
    • 0032949010 scopus 로고    scopus 로고
    • Detection of benzo[a]pyrene diol epoxide-DNA adducts in embryos from smoking couples: evidence for transmission by spermatozoa
    • Zenzes M.T. Puy L. Bielecki R. Reed T.E. Detection of benzo[a]pyrene diol epoxide-DNA adducts in embryos from smoking couples: evidence for transmission by spermatozoa. Mol Hum Reprod. 1999; 5 (2): 125 - 131.
    • (1999) Mol Hum Reprod , vol.5 , Issue.2 , pp. 125-131
    • Zenzes, M.T.1    Puy, L.2    Bielecki, R.3    Reed, T.E.4
  • 68
    • 0032875814 scopus 로고    scopus 로고
    • Cocaine induced apoptosis in rat testes
    • Li H. Jian Y. Rajpurkar R. Dhabuwala C.B. Cocaine induced apoptosis in rat testes. J Urol. 1999; 162 (1): 213 - 216.
    • (1999) J Urol , vol.162 , Issue.1 , pp. 213-216
    • Li, H.1    Jian, Y.2    Rajpurkar, R.3    Dhabuwala, C.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.