-
1
-
-
24744453350
-
Treatment of aortic disease in patients with Marfan syndrome
-
Milewicz DM, Dietz HC, Miller DC. Treatment of aortic disease in patients with Marfan syndrome. Circulation. 2005;111:e150-e157.
-
(2005)
Circulation
, vol.111
-
-
Milewicz, D.M.1
Dietz, H.C.2
Miller, D.C.3
-
2
-
-
0035910615
-
Phenotypic alteration of vascular smooth muscle cells precedes elastolysis in a mouse model of Marfan syndrome
-
Bunton TE, Biery NJ, Myers L, Gayraud B, Ramirez F, Dietz HC. Phenotypic alteration of vascular smooth muscle cells precedes elastolysis in a mouse model of Marfan syndrome. Circ Res. 2001;88:37-43. (Pubitemid 32064080)
-
(2001)
Circulation Research
, vol.88
, Issue.1
, pp. 37-43
-
-
Bunton, T.E.1
Jensen Biery, N.2
Myers, L.3
Gayraud, B.4
Ramirez, F.5
Dietz, H.C.6
-
3
-
-
4043070821
-
Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome
-
DOI 10.1172/JCI200420641
-
Judge DP, Biery NJ, Keene DR, Geubtner J, Myers L, Huso DL, Sakai LY, Dietz HC. Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome. J Clin Invest. 2004; 114:172-181. (Pubitemid 39071622)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.2
, pp. 172-181
-
-
Judge, D.P.1
Biery, N.J.2
Keene, D.R.3
Geubtner, J.4
Myers, L.5
Huso, D.L.6
Sakai, L.Y.7
Dietz, H.C.8
-
4
-
-
0037373277
-
Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome
-
DOI 10.1038/ng1116
-
Neptune ER, Frischmeyer PA, Arking DE, Myers L, Bunton TE, Gayraud B, Ramirez F, Sakai LY, Dietz HC. Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome. Nat Genet. 2003;33: 407-411. (Pubitemid 36278859)
-
(2003)
Nature Genetics
, vol.33
, Issue.3
, pp. 407-411
-
-
Neptune, E.R.1
Frischmeyer, P.A.2
Arking, D.E.3
Myers, L.4
Bunton, T.E.5
Gayraud, B.6
Ramirez, F.7
Sakai, L.Y.8
Dietz, H.C.9
-
5
-
-
0028883828
-
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group
-
Shepherd J, Cobbe SM, Ford I, Isles CG, Lorimer AR, MacFarlane PW, McKillop JH, Packard CJ. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. N Engl J Med. 1995;333:1301-1307.
-
(1995)
N Engl J Med
, vol.333
, pp. 1301-1307
-
-
Shepherd, J.1
Cobbe, S.M.2
Ford, I.3
Isles, C.G.4
Lorimer, A.R.5
MacFarlane, P.W.6
McKillop, J.H.7
Packard, C.J.8
-
6
-
-
0032169240
-
Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels
-
Ridker PM, Rifai N, Pfeffer MA, Sacks FM, Moye LA, Goldman S, Flaker GC, Braunwald E. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events (CARE) Investigators Circulation. 1998;98:839-844. (Pubitemid 28397432)
-
(1998)
Circulation
, vol.98
, Issue.9
, pp. 839-844
-
-
Ridker, P.M.1
Rifai, N.2
Pfeffer, M.A.3
Sacks, F.M.4
Moye, L.A.5
Goldman, S.6
Flaker, G.C.7
Braunwald, E.8
-
7
-
-
0035916233
-
Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization
-
Crisby M, Nordin-Fredriksson G, Shah PK, Yano J, Zhu J, Nilsson J. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation. 2001; 103:926-933. (Pubitemid 32183796)
-
(2001)
Circulation
, vol.103
, Issue.7
, pp. 926-933
-
-
Crisby, M.1
Nordin-Fredriksson, G.2
Shah, P.K.3
Yano, J.4
Zhu, J.5
Nilsson, J.6
-
8
-
-
4143093784
-
Effects of pravastatin on progression of glucose intolerance and cardiovascular remodeling in a type II diabetes model
-
DOI 10.1016/j.jacc.2004.04.050, PII S0735109704010915
-
Yu Y, Ohmori K, Chen Y, Sato C, Kiyomoto H, Shinomiya K, Takeuchi H, Mizushige K, Kohno M. Effects of pravastatin on progression of glucose intolerance and cardiovascular remodeling in a type II diabetes model. J Am Coll Cardiol. 2004;44:904-913. (Pubitemid 39099592)
-
(2004)
Journal of the American College of Cardiology
, vol.44
, Issue.4
, pp. 904-913
-
-
Yu, Y.1
Ohmori, K.2
Chen, Y.3
Sato, C.4
Kiyomoto, H.5
Shinomiya, K.6
Takeuchi, H.7
Mizushige, K.8
Kohno, M.9
-
9
-
-
77649129149
-
Losartan therapy in adults with Marfan syndrome: Study protocol of the multi-center randomized controlled COMPARE trial
-
Radonic T, de Witte P, Baars MJ, Zwinderman AH, Mulder BJ, Groenink M. Losartan therapy in adults with Marfan syndrome: study protocol of the multi-center randomized controlled COMPARE trial. Trials. 2010;11:3.
-
(2010)
Trials.
, vol.11
, pp. 3
-
-
Radonic, T.1
De Witte, P.2
Baars, M.J.3
Zwinderman, A.H.4
Mulder, B.J.5
Groenink, M.6
-
10
-
-
33645672459
-
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome
-
Habashi JP, Judge DP, Holm TM, Cohn RD, Loeys BL, Cooper TK, Myers L, Klein EC, Liu G, Calvi C, Podowski M, Neptune ER, Halushka MK, Bedja D, Gabrielson K, Rifkin DB, Carta L, Ramirez F, Huso DL, Dietz HC. Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science. 2006;312:117-121.
-
(2006)
Science
, vol.312
, pp. 117-121
-
-
Habashi, J.P.1
Judge, D.P.2
Holm, T.M.3
Cohn, R.D.4
Loeys, B.L.5
Cooper, T.K.6
Myers, L.7
Klein, E.C.8
Liu, G.9
Calvi, C.10
Podowski, M.11
Neptune, E.R.12
Halushka, M.K.13
Bedja, D.14
Gabrielson, K.15
Rifkin, D.B.16
Carta, L.17
Ramirez, F.18
Huso, D.L.19
Dietz, H.C.20
more..
-
11
-
-
0026215301
-
The new stereological methods for interpreting functional morphology from slices of cells and organs
-
Mayhew TM. The new stereological methods for interpreting functional morphology from slices of cells and organs. Exp Physiol. 1991;76: 639-665.
-
(1991)
Exp Physiol
, vol.76
, pp. 639-665
-
-
Mayhew, T.M.1
-
12
-
-
0030963981
-
Neuron volume in the ventral horn in Wobbler mouse motoneuron disease: A light microscope stereological study
-
DOI 10.1017/S0021878297002203
-
Dockery P, Tang Y, Morais M, Vacca-Galloway LL. Neuron volume in the ventral horn in Wobbler mouse motoneuron disease: a light microscope stereological study. J Anat. 1997;191(Pt 1):89-98. (Pubitemid 27385106)
-
(1997)
Journal of Anatomy
, vol.191
, Issue.1
, pp. 89-98
-
-
Dockery, P.1
Tang, Y.2
Morais, M.3
Vacca-Galloway, L.L.4
-
13
-
-
34848842170
-
Fibrillin-rich microfibrils: Structural determinants of morphogenetic and homeostatic events
-
DOI 10.1002/jcp.21189
-
Ramirez F, Dietz HC. Fibrillin-rich microfibrils: Structural determinants of morphogenetic and homeostatic events. J Cell Physiol. 2007;213: 326-330. (Pubitemid 47509709)
-
(2007)
Journal of Cellular Physiology
, vol.213
, Issue.2
, pp. 326-330
-
-
Ramirez, F.1
Dietz, H.C.2
-
14
-
-
34250869487
-
Marfan syndrome: Clinical diagnosis and management
-
DOI 10.1038/sj.ejhg.5201851, PII 5201851
-
Dean JC. Marfan syndrome: clinical diagnosis and management. Eur J Hum Genet. 2007;15:724-733. (Pubitemid 46969881)
-
(2007)
European Journal of Human Genetics
, vol.15
, Issue.7
, pp. 724-733
-
-
Dean, J.C.S.1
-
15
-
-
15244363856
-
TGF-β-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome
-
DOI 10.1172/JCI200422715
-
Ng CM, Cheng A, Myers LA, Martinez-Murillo F, Jie C, Bedja D, Gabrielson KL, Hausladen JM, Mecham RP, Judge DP, Dietz HC. TGFbeta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome. J Clin Invest. 2004;114:1586-1592. (Pubitemid 40385549)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.11
, pp. 1586-1592
-
-
Ng, C.M.1
Cheng, A.2
Myers, L.A.3
Martinez-Murillo, F.4
Jie, C.5
Bedja, D.6
Gabrielson, K.L.7
Hausladen, J.M.W.8
Mecham, R.P.9
Judge, D.P.10
Dietz, H.C.11
-
16
-
-
34249688228
-
Marfan syndrome: from molecular pathogenesis to clinical treatment
-
DOI 10.1016/j.gde.2007.04.006, PII S0959437X07000718
-
Ramirez F, Dietz HC. Marfan syndrome: from molecular pathogenesis to clinical treatment. Curr Opin Genet Dev. 2007;17:252-258. (Pubitemid 46843550)
-
(2007)
Current Opinion in Genetics and Development
, vol.17
, Issue.3
, pp. 252-258
-
-
Ramirez, F.1
Dietz, H.C.2
-
17
-
-
13044266360
-
Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1
-
DOI 10.1073/pnas.96.7.3819
-
Pereira L, Lee SY, Gayraud B, Andrikopoulos K, Shapiro SD, Bunton T, Biery NJ, Dietz HC, Sakai LY, Ramirez F. Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1. Proc Natl Acad Sci USA. 1999;96:3819-3823. (Pubitemid 29168994)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.7
, pp. 3819-3823
-
-
Pereira, L.1
Lee, S.Y.2
Gayraud, B.3
Andrikopoulos, K.4
Shapiro, S.D.5
Bunton, T.6
Biery, N.J.7
Dietz, H.C.8
Sakai, L.Y.9
Ramirez, F.10
-
18
-
-
15444372697
-
Plaque rupture after short periods of fat feeding in the apolipoprotein E-knockout mouse: Model characterization and effects of pravastatin treatment
-
DOI 10.1161/01.CIR.0000158435.98035.8D
-
Johnson J, Carson K, Williams H, Karanam S, Newby A, Angelini G, George S, Jackson C. Plaque rupture after short periods of fat feeding in the apolipoprotein E-knockout mouse: model characterization and effects of pravastatin treatment. Circulation. 2005;111:1422-1430. (Pubitemid 40396809)
-
(2005)
Circulation
, vol.111
, Issue.11
, pp. 1422-1430
-
-
Johnson, J.1
Carson, K.2
Williams, H.3
Karanam, S.4
Newby, A.5
Angelini, G.6
George, S.7
Jackson, C.8
-
19
-
-
0035879774
-
Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases
-
DOI 10.1016/S0002-9149(01)01616-2, PII S0002914901016162
-
Kalela A, Laaksonen R, Lehtimaki T, Koivu TA, Hoyhtya M, Janatuinen T, Pollanen P, Vesalainen R, Saikku P, Knuuti J, Nikkari ST. Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases. Am J Cardiol. 2001;88:173-175, A176. (Pubitemid 32607707)
-
(2001)
American Journal of Cardiology
, vol.88
, Issue.2
, pp. 173-175
-
-
Kalela, A.1
Laaksonen, R.2
Lehtimaki, T.3
Koivu, T.A.4
Hoyhtya, M.5
Janatuinen, T.6
Pollanen, P.7
Vesalainen, R.8
Saikku, P.9
Knuuti, J.10
Nikkari, S.T.11
-
20
-
-
33748767111
-
Therapeutic intervention based on protein prenylation and associated modifications
-
DOI 10.1038/nchembio818, PII NCHEMBIO818
-
Gelb MH, Brunsveld L, Hrycyna CA, Michaelis S, Tamanoi F, Van Voorhis WC, Waldmann H. Therapeutic intervention based on protein prenylation and associated modifications. Nat Chem Biol. 2006;2: 518-528. (Pubitemid 44413234)
-
(2006)
Nature Chemical Biology
, vol.2
, Issue.10
, pp. 518-528
-
-
Gelb, M.H.1
Brunsveld, L.2
Hrycyna, C.A.3
Michaelis, S.4
Tamanoi, F.5
Van Voorhis, W.C.6
Waldmann, H.7
-
21
-
-
0037625637
-
Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages
-
DOI 10.1161/01.ATV.0000068646.76823.AE
-
Luan Z, Chase AJ, Newby AC. Statins inhibit secretion of metalloproteinases-1,-2,-3, and-9 from vascular smooth muscle cells and macrophages. Arterioscler Thromb Vasc Biol. 2003;23:769-775. (Pubitemid 36566165)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.5
, pp. 769-775
-
-
Luan, Z.1
Chase, A.J.2
Newby, A.C.3
-
22
-
-
77955473542
-
Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome
-
e2
-
Yang HH, Kim JM, Chum E, van Breemen C, Chung AW. Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome. J Thorac Cardiovasc Surg. 2010;140:305-312.e2.
-
(2010)
J Thorac Cardiovasc Surg.
, vol.140
, pp. 305-312
-
-
Yang, H.H.1
Kim, J.M.2
Chum, E.3
Van Breemen, C.4
Chung, A.W.5
|