In vivo and ex vivo percutaneous absorption of [ 14C]-bisphenol A in rats: A possible extrapolation to human absorption?

Archives of Toxicology

Volumn 85, Issue 9, 2011, Pages 1035-1043

  Marquet, Fabrice ^a   Payan, Jean Paul ^a   Beydon, Dominique ^a   Wathier, Ludivine ^a   Grandclaude, Marie Christine ^a   Ferrari, Elisabeth ^a  

^a INSTITUT NATIONAL DE RECHERCHE ET DE SÉCURITÉ   (France)

Author keywords

Bisphenol A; Ex vivo; Human; In vivo; Percutaneous absorption; Rat

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; CARBON 14;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DIETARY INTAKE; EX VIVO STUDY; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MALE; METABOLISM; NONHUMAN; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; RAT; SKIN ABSORPTION; SKIN PERMEABILITY;

ADMINISTRATION, CUTANEOUS; AIR POLLUTANTS, OCCUPATIONAL; ANIMALS; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIFFUSION CHAMBERS, CULTURE; FECES; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MODELS, BIOLOGICAL; PHENOLS; PREDICTIVE VALUE OF TESTS; RATS; RATS, SPRAGUE-DAWLEY; SKIN; SKIN ABSORPTION; SPECIES SPECIFICITY;

ANIMALIA; RATTUS; RODENTIA;

EID: 80052718466     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0651-z     Document Type: Article

References (29)

1. AS Al-Hiyasat H Darmani AM Elbethiea 2002 Effects of bisphenol A on adult male mouse fertility Eur J Oral Sci 110 163 167 12013561 10.1034/j.1600-0722. 2002.11201.x 1:CAS:528:DC%2BD38XktF2gtbk%3D
2. S Biedermann P Tschudin K Grob 2010 Transfer of bisphenol A from thermal printer paper to the skin Anal Bioannal Chem 398 571 576 10.1007/s00216-010- 3936-9 1:CAS:528:DC%2BC3cXos1ait7k%3D
3. PJ Boogaard MA Denneman NJ Van Sittert 2000 Dermal penetration and metabolism of five glycidyl ethers in human, rat and mouse skin Xenobiotica 30 469 483 10875681 10.1080/004982500237488 1:CAS:528:DC%2BD3cXktF2ltbY%3D (Pubitemid 30639140)
4. E Burridge 2003 Bisphenol A: product profile Eur Chem News 17 14 20
5. AM Calafat Z Kuklenyik JA Reidy SP Caudill J Ekong LL Needham 2005 Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population Environ Health Perspect 113 391 395 15811827 10.1289/ehp.7534 1:CAS:528:DC%2BD2MXjvFOktrc%3D (Pubitemid 40601814)
6. JY Domoradzki LH Pottenger CM Thornton SC Hansen TL Card DA Markham MD Dryzga RN Shiotsuka JM Waechter Jr 2003 Metabolism and pharmacokinetics of bisphenol A (BPA) and the embryo-fetal distribution of BPA-monoglucuronide in CD Sprague-Dawley rats at three gestational stages Toxicol Sci 76 21 34 12915710 10.1093/toxsci/kfg206 1:CAS:528:DC%2BD3sXosVeqsrY%3D (Pubitemid 37361882)
7. ECETOC (1993) Percutaneous absorption. Monograph report no 20
8. EFSA Panel on food contact materials, enzymes, flavourings and processing aids (CEF) (2010) Scientific opinion on bisphenol A: evaluation of a study investigating its neurodevlopmental toxicity, review of recent scientific literature on its toxicity and advice on the Danish risk assessment of bisphenol A. EFSA J 8(9):1829 [110 pp]
9. PG Hewitt J Perkins SA Hotchkiss 2000 Metabolism of fluroxypyr, fluroxypyr methyl ester, and the herbicide fluroxypyr methylheptyl ester. I: during percutaneous absorption through fresh rat and human skin in vitro Drug Metab Dispos 28 748 754 10859147 1:CAS:528:DC%2BD3cXks12is7g%3D (Pubitemid 30470823)
10. N Kaddar C Harthe H Dechaud E Mappus M Pugeat 2008 Cutaneous penetration of bisphenol A in pig skin J Toxicol Environ Health 71 471 473 10.1080/15287390801906824 1:CAS:528:DC%2BD1cXjtFSisLo%3D (Pubitemid 351380288)
11. BW Kemppainen M Mehta R Stafford RT Riley 1992 Effect of vehicle on skin penetration and retention of a lipophilic red tide toxin (PbTx-3) Toxicon 30 931 935 1523686 10.1016/0041-0101(92)90393-J 1:CAS:528:DyaK38Xlt1Kisb8%3D
12. H Kurebayashi R Harada RK Stewart H Numata Y Ohno 2002 Disposition of low dose of bisphenol A in male and female cynomolgus monkeys Toxicol Sci 68 32 42 12075108 10.1093/toxsci/68.1.32 1:CAS:528:DC%2BD38XlsVSnurs%3D (Pubitemid 34785227)
13. 14C]-bisphenol A in male rats and its main biliary excretion as BPA glucuronide Toxicol Sci 73 17 25 12700409 10.1093/toxsci/kfg040 1:CAS:528:DC%2BD3sXjsVKltLc%3D (Pubitemid 36609081)
14. IA Lang TS Galloway A Scarlett WE Henley M Depledge MelzerD WallaceRB 2008 Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults JAMA 300 1303 1310 18799442 10.1001/jama.300.11.1303 1:CAS:528:DC%2BD1cXhtFGis7nE
15. A Matsumoto N Kunugita K Kitagawa T Isse T Oyama GL Foureman M Morita T Kawamoto 2003 Bisphenol A levels in human urine Environ Health Perspect 111 101 104 12515686 10.1289/ehp.5512 1:CAS:528:DC%2BD3sXht1Wqs7c%3D
16. NTP-CEHRH monograph on the potential human reproductive and developmental effects of bisphenol A (2008) U.S. department of health and human services, NIH publication no 08-5994, p 321
17. P Palanza KL Howdeshell S Parmigiani FS vom Saal 2002 Exposure to a low dose of bisphenol A during fetal life or in adulthood alters maternal behavior in mice Environ Health Perspect 110 415 422 12060838 10.1289/ehp.02110s3415 1:CAS:528:DC%2BD38XltlWjsbs%3D (Pubitemid 34669809)
18. 14C]di-N-butylphthalate in rat Drug Metab Dispos 29 843 854 11353753 1:CAS:528:DC%2BD3MXjvFantrw%3D (Pubitemid 32488641)
19. JP Payan M Lafontaine P Simon F Marquet C Champmartin-Gendre D Beydon E Ferrari 2008 In vivo and in vitro percutaneous absorption of [14]pyrene in Sprague-Dawley male rats: skin reservoir effect and consequence on urinary 1-OH pyrene excretion Arch Toxicol 82 739 747 18421439 10.1007/s00204-008-0300-3 1:CAS:528:DC%2BD1cXht1ehtbvL
20. JP Payan M Lafontaine P Simon F Marquet C Champmartin-Gendre D Beydon L Wathier E Ferrari 2009 3-Hydroxybenzo(a)pyrene as a biomarker of dermal exposure to benzo(a)pyrene Arch Toxicol 83 873 883 19526226 10.1007/s00204-009-0440-0 1:CAS:528:DC%2BD1MXntF2mtr0%3D
21. BS Rubin MK Murray DA Damassa JC King AM Soto 2001 Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels Environ Health Perspect 109 675 680 11485865 10.1289/ehp.01109675 1:CAS:528:DC%2BD3MXmtFOjsb8%3D (Pubitemid 32785423)
22. J Sekizawa 2008 Low-dose effects of bisphenol A: a serious threat to human health? J Toxicol Sci 33 389 403 18827439 10.2131/jts.33.389 1:CAS:528:DC%2BD1cXht1Omtr7L
23. JJM Van de Sandt JA van Burgsteden S Cage PL Carmichael I Dick S Kenyon K Korinth JC Limasset WJM Maas L Montomoli JB Nielsen JP Payan E Robinson P Sartorelli KH Schaller SC Wilkinson F Williams 2004 In vitro predictions of skin absorption of caffeine, testosterone and benzoic acid: a multi-centre comparison study Regul Toxicol Pharmacol 39 271 281 15135208 10.1016/j.yrtph.2004.02.004 (Pubitemid 38596765)
24. C Vickers 1963 Existence of reservoir in the stratum corneum. Experimental proof Arch Dermatol 88 21 23
25. W Völkel M Kiranoglu H Fromme 2008 Determination of free and total bisphenol A in human urine to assess daily uptake as a basis for a valid risk assessment Toxicol Lett 179 155 162 18579321 10.1016/j.toxlet.2008.05.002
26. W Völkel T Colnot GA Csanady JG Filser W Dekant 2002 Metabolism and kinetics of bisphenol A in humans at low doses following oral administration Chem Res Toxicol 15 1281 1287 12387626 10.1021/tx025548t (Pubitemid 35222197)
27. FS Vom Saal C Hughes 2005 An extensive new literature concerning low-dose effect of bisphenol A shows the need for a new risk assessment Environ Health Perspect 113 926 933 16079060 10.1289/ehp.7713 1:CAS:528:DC%2BD2MXpslSktbs%3D (Pubitemid 41149619)
28. Zalko D, Jacques C, Duplan H, Bruel S, Perdu E (2010) Viable skin efficiently absorbs and metabolizes Bisphenol A. Chemosphere (in press)
29. Q Zhang JE Grice G Wang MS Roberts 2009 Cutaneous metabolism in transdermal drug delivery Curr Drug Metab 10 227 235 19442085 10.2174/138920009787846350 1:CAS:528:DC%2BD1MXmtlGrsLg%3D