Molecular genetic and functional characterization implicate muscle-restricted coiled-coil gene (MURC) as a causal gene for familial dilated cardiomyopathy

Circulation: Cardiovascular Genetics

Volumn 4, Issue 4, 2011, Pages 349-358

  Rodriguez, Gabriela ^a   Ueyama, Tomomi ^b   Ogata, Takehiro ^b   Czernuszewicz, Grazyna ^a   Tan, Yanli ^a   Dorn II, Gerald W ^c   Bogaev, Roberta ^d   Amano, Katsuya ^b   Oh, Hidemasa ^e   Matsubara, Hiroaki ^b   Willerson, James T ^a,d   Marian, Ali J ^a,d  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ST LUKE S EPISCOPAL HOSPITAL   (United States)

^e OKAYAMA UNIVERSITY HOSPITAL   (Japan)

Author keywords

Cardiomyopathy; Genetics; Heart failure; Mutation; RhoA

Indexed keywords

ALPHA TROPOMYOSIN; AMINO ACID; MUTANT PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ACTC1 GENE; ADULT; AFRICAN AMERICAN; ANIMAL CELL; ARTICLE; CAUCASIAN; CELL GROWTH; CELL SIZE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DELETION MUTANT; DISEASE COURSE; DISEASE MARKER; ELECTROCARDIOGRAM; ENZYME ACTIVATION; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; FEMALE; FRAMESHIFT MUTATION; GENE; GENE SEQUENCE; GENOTYPE; HEART ATRIUM ARRHYTHMIA; HEART FAILURE; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONDUCTION DISTURBANCE; HEART TRANSPLANTATION; HETEROZYGOTE; HUMAN; INHERITANCE; LMNA GENE; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; MUSCLE FIBER CULTURE; MUSCLE RESTRICTED COILED COIL GENE; MYBPC3 GENE; MYH7 GENE; MYOZ2 GENE; NEWBORN; NONHUMAN; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; RACE DIFFERENCE; RAT; REGULATOR GENE; SHORT TANDEM REPEAT; TNNI3 GENE; TNNT2 GENE; VIRUS RECOMBINANT; WILD TYPE;

ANIMALS; CARDIOMYOPATHY, DILATED; CARDIOMYOPATHY, HYPERTROPHIC; CASE-CONTROL STUDIES; DNA MUTATIONAL ANALYSIS; HUMANS; MUSCLE CELLS; MUSCLE PROTEINS; MUTANT PROTEINS; MUTATION; RATS; TRANSFECTION;

MUS; RATTUS;

EID: 80052718007     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.111.959866     Document Type: Article

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