Cadmium chloride inhibits lactate gluconeogenesis in isolated human renal proximal tubules: A cellular metabolomic approach with 13C-NMR

Archives of Toxicology

Volumn 85, Issue 9, 2011, Pages 1067-1077

  Faiz, Hassan ^a   Conjard Duplany, Agnès ^a   Boghossian, Michelle ^a   Martin, Guy ^a   Baverel, Gabriel ^a   Ferrier, Bernard ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Cadmium; Gluconeogenesis; Human; Lactate; Metabolism; Nephrotoxicity

Indexed keywords

ACETYL COENZYME A; ADENOSINE TRIPHOSPHATE; ALANINE AMINOTRANSFERASE; CADMIUM CHLORIDE; CARBON 13; COENZYME A; GLUCOSE 6 PHOSPHATASE; GLUTATHIONE; LACTATE DEHYDROGENASE; LACTIC ACID; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PYRUVATE CARBOXYLASE; TRICARBOXYLIC ACID;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME METABOLISM; GLUCONEOGENESIS; GLUCOSE UTILIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CELL; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE DISORDER; METABOLOMICS; NEPHROTOXICITY; PRIORITY JOURNAL;

CADMIUM CHLORIDE; CARBON ISOTOPES; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; GLUCONEOGENESIS; HUMANS; KIDNEY TUBULES, PROXIMAL; LACTATES; MAGNETIC RESONANCE SPECTROSCOPY; METABOLOMICS; TISSUE CULTURE TECHNIQUES;

EID: 80052716991     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-010-0633-6     Document Type: Article

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