Synthesis of the C19 methyl ether of aspercyclide A via germyl-Stille macrocyclisation and ELISA evaluation of both enantiomers following optical resolution

Organic and Biomolecular Chemistry

Volumn 9, Issue 19, 2011, Pages 6814-6824

  Carr, James L ^a   Sejberg, Jimmy J P ^a   Saab, Fabienne ^b   Holdom, Mary D ^b   Davies, Anna M ^b   White, Andrew J P ^a   Leatherbarrow, Robin J ^a   Beavil, Andrew J ^b   Sutton, Brian J ^b   Lindell, Stephen D ^c   Spivey, Alan C ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

^c BAYER CROPSCIENCE AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGIC DISORDER; MACROCYCLICS; METHYL ETHERS; NATURAL PRODUCTS; OPTICAL RESOLUTION; PROTEIN-PROTEIN INTERACTIONS; SIGNAL TRANSDUCTION PATHWAYS;

CHIRALITY; COPYING; CRYSTAL STRUCTURE; ENANTIOMERS; ORGANIC COMPOUNDS; SIGNAL TRANSDUCTION; SYNTHESIS (CHEMICAL);

ETHERS;

ASPERCYCLIDE A; ETHER DERIVATIVE; LACTONE; MACROCYCLIC COMPOUND;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; STEREOISOMERISM; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

CHEMISTRY TECHNIQUES, SYNTHETIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; LACTONES; MACROCYCLIC COMPOUNDS; METHYL ETHERS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 80052705370     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c1ob05862b     Document Type: Article

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