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Volumn 5, Issue , 2010, Pages 1-31

Molecular pathogenesis of necrotizing fasciitis

Author keywords

Flesh eating disease; Group A Streptococcus; Severe invasive infection

Indexed keywords

BACTERIAL PROTEIN; BACTERIUM ANTIBODY; CLINDAMYCIN; GAMMA INTERFERON; IMMUNOGLOBULIN; INTERLEUKIN 1; MATRIX METALLOPROTEINASE; METAL TRANSPORTER OF STREPTOCOCCUS PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; PENICILLIN G; PRSA PROTEIN; SPEB PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VANCOMYCIN; VIRULENCE FACTOR;

EID: 77949890164     PISSN: 15534006     EISSN: 15534014     Source Type: Book Series    
DOI: 10.1146/annurev-pathol-121808-102135     Document Type: Review
Times cited : (112)

References (150)
  • 1
    • 0036891957 scopus 로고    scopus 로고
    • Evolving microbes and re-emerging streptococcal disease
    • Krause RM. 2002. Evolving microbes and re-emerging streptococcal disease. Clin. Lab. Med. 22:835-848
    • (2002) Clin. Lab. Med. , vol.22 , pp. 835-848
    • Krause, R.M.1
  • 2
    • 34347334334 scopus 로고    scopus 로고
    • New understanding of the group A Streptococcus pathogenesis cycle
    • Tart AH, Walker MJ, Musser JM. 2007. New understanding of the group A Streptococcus pathogenesis cycle. Trends Microbiol. 15:318-325
    • (2007) Trends Microbiol , vol.15 , pp. 318-325
    • Tart, A.H.1    Walker, M.J.2    Musser, J.M.3
  • 3
    • 34848846150 scopus 로고    scopus 로고
    • The epidemiology of invasive group A streptococcal infection and potential vaccine implications: United States, 2000-2004
    • O'Loughlin RE, Roberson A, Cieslak PR, Lynfield R, Gershman K, et al. 2007. The epidemiology of invasive group A streptococcal infection and potential vaccine implications: United States, 2000-2004. Clin. Infect. Dis. 45:853-862
    • (2007) Clin. Infect. Dis. , vol.45 , pp. 853-862
    • O'Loughlin, R.E.1    Roberson, A.2    Cieslak, P.R.3    Lynfield, R.4    Gershman, K.5
  • 6
    • 65249093620 scopus 로고    scopus 로고
    • Clinical and microbiological characteristics of severe Streptococcus pyogenes disease in Europe
    • Luca-Harari B, Darenberg J, Neal S, Siljander T, Strakova L, et al. 2009. Clinical and microbiological characteristics of severe Streptococcus pyogenes disease in Europe. J. Clin. Microbiol. 47:1155-1165
    • (2009) J. Clin. Microbiol. , vol.47 , pp. 1155-1165
    • Luca-Harari, B.1    Darenberg, J.2    Neal, S.3    Siljander, T.4    Strakova, L.5
  • 7
    • 58149313653 scopus 로고    scopus 로고
    • Molecular mechanisms underlying group A streptococcal pathogenesis
    • Olsen RJ, Shelburne SA, Musser JM. 2009. Molecular mechanisms underlying group A streptococcal pathogenesis. Cell Microbiol. 11:1-12
    • (2009) Cell Microbiol. , vol.11 , pp. 1-12
    • Olsen, R.J.1    Shelburne, S.A.2    Musser, J.M.3
  • 8
    • 40749125722 scopus 로고    scopus 로고
    • Severe necrotizing fasciitis in a human immunodeficiency virus-positive patient caused by methicillin-resistant Staphylococcus aureus
    • Olsen RJ, Burns KM, Chen L, Kreiswirth BN,Musser JM. 2008. Severe necrotizing fasciitis in a human immunodeficiency virus-positive patient caused by methicillin-resistant Staphylococcus aureus. J. Clin. Microbiol. 46:1144-1147
    • (2008) J. Clin. Microbiol. , vol.46 , pp. 1144-1147
    • Olsen, R.J.1    Burns, K.M.2    Chen, L.3    Kreiswirth, B.N.4    Musser, J.M.5
  • 9
    • 43149108342 scopus 로고    scopus 로고
    • Community-associated methicillin-resistant Staphylococcus aureus skin infections: Advances toward identifying the key virulence factors
    • Nygaard TK, DeLeo FR, Voyich JM. 2008. Community-associated methicillin-resistant Staphylococcus aureus skin infections: advances toward identifying the key virulence factors. Curr. Opin. Infect. Dis. 21:147-152
    • (2008) Curr. Opin. Infect. Dis. , vol.21 , pp. 147-152
    • Nygaard, T.K.1    De Leo, F.R.2    Voyich, J.M.3
  • 11
    • 66849099117 scopus 로고    scopus 로고
    • Adherence of Streptococcus pyogenes to human epithelial cells is modulated by Haemophilus influenzae
    • Xu Q, Pichichero ME, Zeng M. 2009. Adherence of Streptococcus pyogenes to human epithelial cells is modulated by Haemophilus influenzae. Scand. J. Infect. Dis. 41:244-251
    • (2009) Scand. J. Infect. Dis. , vol.41 , pp. 244-251
    • Xu, Q.1    Pichichero, M.E.2    Zeng, M.3
  • 12
    • 4143067139 scopus 로고    scopus 로고
    • Fournier's gangrene: Experience with 25 patients and use of Fournier's gangrene severity index score
    • Yeniyol CO, Suelozgen T, Arslan M, Ayder AR. 2004. Fournier's gangrene: experience with 25 patients and use of Fournier's gangrene severity index score. Urology 64:218-222
    • (2004) Urology , vol.64 , pp. 218-222
    • Yeniyol, C.O.1    Suelozgen, T.2    Arslan, M.3    Ayder, A.R.4
  • 13
    • 84882879888 scopus 로고
    • Hippocrates on necrotising fasciitis
    • Descamps V, Aitken J, Lee MG. 1994. Hippocrates on necrotising fasciitis. Lancet 344:556
    • (1994) Lancet , vol.344 , pp. 556
    • Descamps, V.1    Aitken, J.2    Lee, M.G.3
  • 14
    • 0001270113 scopus 로고
    • Necrotizing fasciitis
    • Wilson B. 1952. Necrotizing fasciitis. Am. Surg. 18:416-431
    • (1952) Am. Surg. , vol.18 , pp. 416-431
    • Wilson, B.1
  • 15
    • 49349113964 scopus 로고    scopus 로고
    • Approach to debridement in necrotizing fasciitis
    • Wong CH, Yam AK, Tan AB, Song C. 2008. Approach to debridement in necrotizing fasciitis. Am. J. Surg. 196:e19-24
    • (2008) Am. J. Surg. , vol.196
    • Wong, C.H.1    Yam, A.K.2    Tan, A.B.3    Song, C.4
  • 16
    • 38849206833 scopus 로고    scopus 로고
    • Autopsy cases of fulminant-type bacterial infection with necrotizing fasciitis: Group A (beta) hemolytic Streptococcus pyogenes versus Vibrio vulnificus infection
    • Tajiri T, Tate G, Akita H, Ohike N, Masunaga A, et al. 2008. Autopsy cases of fulminant-type bacterial infection with necrotizing fasciitis: group A (beta) hemolytic Streptococcus pyogenes versus Vibrio vulnificus infection. Pathol. Int. 58:196-202
    • (2008) Pathol. Int. , vol.58 , pp. 196-202
    • Tajiri, T.1    Tate, G.2    Akita, H.3    Ohike, N.4    Masunaga, A.5
  • 17
    • 24644475670 scopus 로고    scopus 로고
    • Vascular dysfunction and ischemic destruction of tissue in Streptococcus pyogenes infection: The role of streptolysin O-induced platelet/neutrophil complexes
    • Bryant AE, Bayer CR, Chen RY, Guth PH, Wallace RJ, Stevens DL. 2005. Vascular dysfunction and ischemic destruction of tissue in Streptococcus pyogenes infection: the role of streptolysin O-induced platelet/neutrophil complexes. J. Infect. Dis. 192:1014-1022
    • (2005) J. Infect. Dis. , vol.192 , pp. 1014-1022
    • Bryant, A.E.1    Bayer, C.R.2    Chen, R.Y.3    Guth, P.H.4    Wallace, R.J.5    Stevens, D.L.6
  • 18
    • 34247510565 scopus 로고    scopus 로고
    • Prognostic factors in necrotizing fasciitis and myositis: Analysis of 16 consecutive cases at a single institution in Switzerland
    • Rieger UM, Gugger CY, Farhadi J, Heider I, Andresen R, et al. 2007. Prognostic factors in necrotizing fasciitis and myositis: analysis of 16 consecutive cases at a single institution in Switzerland. Ann. Plast. Surg. 58:523-530
    • (2007) Ann. Plast. Surg. , vol.58 , pp. 523-530
    • Rieger, U.M.1    Gugger, C.Y.2    Farhadi, J.3    Heider, I.4    Andresen, R.5
  • 19
    • 33845939764 scopus 로고    scopus 로고
    • Morbidity and mortality of patients with invasive group A streptococcal infections admitted to the ICU
    • Mehta S, McGeer A, Low DE, Hallett D, Bowman DJ, et al. 2006. Morbidity and mortality of patients with invasive group A streptococcal infections admitted to the ICU. Chest 130:1679-1686
    • (2006) Chest , vol.130 , pp. 1679-1686
    • Mehta, S.1    McGeer, A.2    Low, D.E.3    Hallett, D.4    Bowman, D.J.5
  • 21
    • 14944351056 scopus 로고    scopus 로고
    • Successful management of severe group A streptococcal soft tissue infections using an aggressive medical regimen including intravenous olyspecific immunoglobulin together with a conservative surgical approach
    • Norrby-Teglund A, Muller MP, McGeer A, Gan BS, Guru V, et al. 2005. Successful management of severe group A streptococcal soft tissue infections using an aggressive medical regimen including intravenous polyspecific immunoglobulin together with a conservative surgical approach. Scand. J. Infect. Dis. 37:166-172
    • (2005) Scand. J. Infect. Dis. , vol.37 , pp. 166-172
    • Norrby-Teglund, A.1    Muller, M.P.2    McGeer, A.3    Gan, B.S.4    Guru, V.5
  • 22
    • 0030786631 scopus 로고    scopus 로고
    • Population-based surveillance for group A streptococcal necrotizing fasciitis: Clinical features, prognostic indicators, and microbiologic analysis of seventy-seven cases
    • Ontario Group A Streptococcal Study
    • Kaul R McGeer A Low DE Green K Schwartz B. 1997. Population-based surveillance for group A streptococcal necrotizing fasciitis: Clinical features, prognostic indicators, and microbiologic analysis of seventy-seven cases. Ontario Group A Streptococcal Study. Am. J. Med. 103. 18-24.
    • (1997) Am. J. Med. , vol.103 , pp. 18-24
    • Kaul, R.1    McGeer, A.2    Low, D.E.3    Green, K.4    Schwartz, B.5
  • 23
    • 58349085329 scopus 로고    scopus 로고
    • Case records of the Massachusetts General Hospital. Case 2-2009. A 25-year-old man with pain and swelling of the right hand and hypotension
    • Filbin MR, Ring DC,Wessels MR, Avery LL, Kradin RL. 2009. Case records of the Massachusetts General Hospital. Case 2-2009. A 25-year-old man with pain and swelling of the right hand and hypotension. N. Engl. J. Med. 360:281-290
    • (2009) N. Engl. J. Med. , vol.360 , pp. 281-290
    • Filbin, M.R.1    Ring Dcwessels, M.R.2    Avery, L.L.3    Kradin, R.L.4
  • 24
    • 28844492280 scopus 로고    scopus 로고
    • A pilot study of cytokine levels and white blood cell counts in the diagnosis of necrotizing fasciitis
    • Rodriguez RM, Abdullah R, Miller R, Barry L, Lungstras-Bufler K, et al. 2006. A pilot study of cytokine levels and white blood cell counts in the diagnosis of necrotizing fasciitis. Am. J. Emerg. Med. 24:58-61
    • (2006) Am. J. Emerg. Med. , vol.24 , pp. 58-61
    • Rodriguez, R.M.1    Abdullah, R.2    Miller, R.3    Barry, L.4    Lungstras-Bufler, K.5
  • 25
    • 42149195170 scopus 로고    scopus 로고
    • Necrotizing fasciitis caused by group A Streptococcus with no apparent predisposing factors presenting as acute abdomen
    • Al-Tamimi HA, Thomas L. 2008. Necrotizing fasciitis caused by group A Streptococcus with no apparent predisposing factors presenting as acute abdomen. Int. J. Infect. Dis. 12:332-333
    • (2008) Int. J. Infect. Dis. , vol.12 , pp. 332-333
    • Al-Tamimi, H.A.1    Thomas, L.2
  • 27
    • 35348960997 scopus 로고    scopus 로고
    • Blunt trauma as a risk factor for group A streptococcal necrotizing fasciitis
    • Nuwayhid ZB, Aronoff DM, Mulla ZD. 2007. Blunt trauma as a risk factor for group A streptococcal necrotizing fasciitis. Ann. Epidemiol. 17:878-881
    • (2007) Ann. Epidemiol. , vol.17 , pp. 878-881
    • Nuwayhid, Z.B.1    Aronoff, D.M.2    Mulla, Z.D.3
  • 28
    • 0028271420 scopus 로고
    • Gangrenous streptococcal myositis: Case report
    • Hird B, Byrne K. 1994. Gangrenous streptococcal myositis: case report. J. Trauma 36:589-591
    • (1994) J. Trauma , vol.36 , pp. 589-591
    • Hird, B.1    Byrne, K.2
  • 29
    • 40749083853 scopus 로고    scopus 로고
    • Onset of streptococcal toxic shock syndrome is accelerated by bruising in a mouse model
    • Seki M, Saito M, Iida K, Taniai H, Soejima T, et al. 2008. Onset of streptococcal toxic shock syndrome is accelerated by bruising in a mouse model. Microb. Pathog. 44:339-343
    • (2008) Microb. Pathog. , vol.44 , pp. 339-343
    • Seki, M.1    Saito, M.2    Iida, K.3    Taniai, H.4    Soejima, T.5
  • 30
    • 33646478851 scopus 로고    scopus 로고
    • Molecular genetic anatomy of inter-and intraserotype variation in the human bacterial pathogen group A Streptococcus
    • Beres SB, Richter EW, Nagiec MJ, Sumby P, Porcella SF, et al. 2006. Molecular genetic anatomy of inter-and intraserotype variation in the human bacterial pathogen group A Streptococcus. Proc. Natl. Acad. Sci. USA 103:7059-7064
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 7059-7064
    • Beres, S.B.1    Richter, E.W.2    Nagiec, M.J.3    Sumby, P.4    Porcella, S.F.5
  • 31
    • 33744795703 scopus 로고    scopus 로고
    • Group A streptococcal myonecrosis: Increased vimentin expression after skeletal-muscle injury mediates the binding of Streptococcus pyogenes
    • Bryant AE, Bayer CR, Huntington JD, Stevens DL. 2006. Group A streptococcal myonecrosis: Increased vimentin expression after skeletal-muscle injury mediates the binding of Streptococcus pyogenes. J. Infect. Dis. 193:1685-1692
    • (2006) J. Infect. Dis. , vol.193 , pp. 1685-1692
    • Bryant, A.E.1    Bayer, C.R.2    Huntington, J.D.3    Stevens, D.L.4
  • 32
    • 56649088259 scopus 로고    scopus 로고
    • Muscle injury, vimentin expression, and nonsteroidal anti-inflammatory drugs predispose to cryptic group A streptococcal necrotizing infection
    • Hamilton SM, Bayer CR, Stevens DL, Lieber RL, Bryant AE. 2008. Muscle injury, vimentin expression, and nonsteroidal anti-inflammatory drugs predispose to cryptic group A streptococcal necrotizing infection. J. Infect. Dis. 198:1692-1698
    • (2008) J. Infect. Dis. , vol.198 , pp. 1692-1698
    • Hamilton, S.M.1    Bayer, C.R.2    Stevens, D.L.3    Lieber, R.L.4    Bryant, A.E.5
  • 33
    • 0028864198 scopus 로고
    • Could nonsteroidal antiinflammatory drugs (NSAIDs) enhance the progression of bacterial infections to toxic shock syndrome?
    • Stevens DL. 1995. Could nonsteroidal antiinflammatory drugs (NSAIDs) enhance the progression of bacterial infections to toxic shock syndrome? Clin. Infect. Dis. 21:977-980
    • (1995) Clin. Infect. Dis. , vol.21 , pp. 977-980
    • Stevens, D.L.1
  • 34
    • 0037823449 scopus 로고    scopus 로고
    • Assessing the relationship between the use of nonsteroidal antiinflammatory drugs and necrotizing fasciitis caused by group A Streptococcus
    • Aronoff DM, Bloch KC. 2003. Assessing the relationship between the use of nonsteroidal antiinflammatory drugs and necrotizing fasciitis caused by group A Streptococcus. Medicine (Baltim.) 82:225-235
    • (2003) Medicine (Baltim.) , vol.82 , pp. 225-235
    • Aronoff, D.M.1    Bloch, K.C.2
  • 35
    • 85012656216 scopus 로고
    • Studies on the biology of Streptococcus. I. Antigenic pathogenesis research. relationship between strains of Streptococcus haemolyticus
    • Dochez R, Avery OT, Lancefield RC. 1919. Studies on the biology of Streptococcus. I. Antigenic pathogenesis research. relationship between strains of Streptococcus haemolyticus. J. Exp. Med. 30:179-213
    • (1919) J. Exp. Med. , vol.30 , pp. 179-213
    • Dochez, R.1    Avery, O.T.2    Lancefield, R.C.3
  • 36
    • 51849112875 scopus 로고    scopus 로고
    • Genome sequence of a Lancefield group C Streptococcus zooepidemicus strain causing epidemic nephritis: New information about an old disease
    • Beres SB, Sesso R, Pinto SW, Hoe NP, Porcella SF, et al. 2008. Genome sequence of a Lancefield group C Streptococcus zooepidemicus strain causing epidemic nephritis: new information about an old disease. PLoS ONE 3:e3026
    • (2008) PLoS ONE , vol.3
    • Beres, S.B.1    Sesso, R.2    Pinto, S.W.3    Hoe, N.P.4    Porcella, S.F.5
  • 38
    • 0033939735 scopus 로고    scopus 로고
    • Pathogenesis of group A streptococcal infections
    • Cunningham MW. 2000. Pathogenesis of group A streptococcal infections. Clin. Microbiol. Rev. 13:470-511
    • (2000) Clin. Microbiol. Rev. , vol.13 , pp. 470-511
    • Cunningham, M.W.1
  • 39
    • 54249155508 scopus 로고    scopus 로고
    • Rise and persistence of global M1T1 clone of Streptococcus pyogenes
    • Aziz RK, Kotb M. 2008. Rise and persistence of global M1T1 clone of Streptococcus pyogenes. Emerg. Infect. Dis. 14:1511-1517
    • (2008) Emerg. Infect. Dis. , vol.14 , pp. 1511-1517
    • Aziz, R.K.1    Kotb, M.2
  • 40
    • 16844365338 scopus 로고    scopus 로고
    • Invasive group A streptococcal disease in Alberta, Canada (2000 to 2002)
    • Tyrrell GJ, Lovgren M, Kress B, Grimsrud K. 2005. Invasive group A streptococcal disease in Alberta, Canada (2000 to 2002). J. Clin. Microbiol. 43:1678-1683
    • (2005) J. Clin. Microbiol. , vol.43 , pp. 1678-1683
    • Tyrrell, G.J.1    Lovgren, M.2    Kress, B.3    Grimsrud, K.4
  • 41
    • 28244489930 scopus 로고    scopus 로고
    • Toward a genome-wide systems biology analysis of host-pathogen interactions in group A Streptococcus
    • Musser JM, DeLeo FR. 2005. Toward a genome-wide systems biology analysis of host-pathogen interactions in group A Streptococcus. Am. J. Pathol. 167:1461-1472
    • (2005) Am. J. Pathol. , vol.167 , pp. 1461-1472
    • Musser, J.M.1    De Leo, F.R.2
  • 42
    • 0037162559 scopus 로고    scopus 로고
    • Genome sequence of a serotype M3 strain of group A Streptococcus: Phage-encoded toxins, the high-virulence phenotype, and clone emergence
    • Beres SB, Sylva GL, Barbian KD, Lei B, Hoff JS, et al. 2002. Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence. Proc. Natl. Acad. Sci. USA 99:10078-10083
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 10078-1008
    • Beres, S.B.1    Sylva, G.L.2    Barbian, K.D.3    Lei, B.4    Hoff, J.S.5
  • 43
    • 57349084131 scopus 로고    scopus 로고
    • Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenes
    • McShan WM, Ferretti JJ, Karasawa T, Suvorov AN, Lin S, et al. 2008. Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenes. J. Bacteriol. 190:7773-7785
    • (2008) J. Bacteriol. , vol.190 , pp. 7773-7785
    • McShan, W.M.1    Ferretti, J.J.2    Karasawa, T.3    Suvorov, A.N.4    Lin, S.5
  • 44
    • 23944510259 scopus 로고    scopus 로고
    • Genome sequence of a serotype M28 strain of group A Streptococcus: Potential new insights into puerperal sepsis and bacterial disease specificity
    • Green NM, Zhang S, Porcella SF, Nagiec MJ, Barbian KD, et al. 2005. Genome sequence of a serotype M28 strain of group A Streptococcus: potential new insights into puerperal sepsis and bacterial disease specificity. J. Infect. Dis. 192:760-770
    • (2005) J. Infect. Dis. , vol.192 , pp. 760-770
    • Green, N.M.1    Zhang, S.2    Porcella, S.F.3    Nagiec, M.J.4    Barbian, K.D.5
  • 45
    • 3943087577 scopus 로고    scopus 로고
    • Progress toward characterization of the group A Streptococcus metagenome: Complete genome sequence of a macrolide-resistant serotype M6 strain
    • Banks DJ, Porcella SF, Barbian KD, Beres SB, Philips LE, et al. 2004. Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain. J. Infect. Dis. 190:727-738
    • (2004) J. Infect. Dis. , vol.190 , pp. 727-738
    • Banks, D.J.1    Porcella, S.F.2    Barbian, K.D.3    Beres, S.B.4    Philips, L.E.5
  • 47
    • 0037007095 scopus 로고    scopus 로고
    • Genome sequence and cmparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks
    • Smoot JC, Barbian KD, Van Gompel JJ, Smoot LM, Chaussee MS, et al. 2002. Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks. Proc. Natl. Acad. Sci. USA 99:4668-4673
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 4668-4673
    • Smoot, J.C.1    Barbian, K.D.2    Van Gompel, J.J.3    Smoot, L.M.4    Chaussee, M.S.5
  • 48
    • 0038480005 scopus 로고    scopus 로고
    • Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution
    • Nakagawa I, Kurokawa K, Yamashita A, Nakata M, Tomiyasu Y, et al. 2003. Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution. Genome Res. 13:1042-1055
    • (2003) Genome Res. , vol.13 , pp. 1042-1055
    • Nakagawa, I.1    Kurokawa, K.2    Yamashita, A.3    Nakata, M.4    Tomiyasu, Y.5
  • 49
    • 77952917849 scopus 로고    scopus 로고
    • A naturally occurring single nucleotide change decreases necrotizing fasciitis ("flesh-eating") capacity of group A Streptococcus (GAS)
    • Abstr.
    • Olsen RJ, Sitkiewicz I, Ayeras AA, Beres SB, Green NM, et al. 2009. A naturally occurring single nucleotide change decreases necrotizing fasciitis ("flesh-eating") capacity of group A Streptococcus (GAS). FASEB J. 22:594 (Abstr.)
    • (2009) FASEB J. , vol.22 , pp. 594
    • Olsen, R.J.1    Sitkiewicz, I.2    Ayeras, A.A.3    Beres, S.B.4    Green, N.M.5
  • 50
    • 23344444773 scopus 로고    scopus 로고
    • Growth characteristics of and virulence factor production by group A Streptococcus during cultivation in human saliva
    • Shelburne SA 3rd, Granville CN, Tokuyama M, Sitkiewicz I, Patel P, Musser JM. 2005. Growth characteristics of and virulence factor production by group A Streptococcus during cultivation in human saliva. Infect. Immun. 73:4723-4731
    • (2005) Infect. Immun. , vol.73 , pp. 4723-4731
    • Shelburne Iii, S.A.1    Granville, C.N.2    Tokuyama, M.3    Sitkiewicz, I.4    Patel, P.5    Musser, J.M.6
  • 51
    • 27644485867 scopus 로고    scopus 로고
    • Central role of a two-component gene regulatory system of previously unknown function in pathogen persistence in human saliva
    • Shelburne SA, Sumby P, Sitkiewicz I, Granville CN, DeLeo FR, Musser JM. 2005. Central role of a two-component gene regulatory system of previously unknown function in pathogen persistence in human saliva. Proc. Natl. Acad. Sci. USA 102:16037-16042
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 16037-16042
    • Shelburne, S.A.1    Sumby, P.2    Sitkiewicz, I.3    Granville, C.N.4    De Leo, F.R.5    Musser, J.M.6
  • 52
    • 4143122250 scopus 로고    scopus 로고
    • Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infections
    • Beres SB, Sylva GL, Sturdevant DE, Granville CN, Liu M, et al. 2004. Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infections. Proc. Natl. Acad. Sci. USA 101:11833-11838
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 11833-11838
    • Beres, S.B.1    Sylva, G.L.2    Sturdevant, D.E.3    Granville, C.N.4    Liu, M.5
  • 53
    • 13444279883 scopus 로고    scopus 로고
    • Extracellular deoxyribonuclease made by group A Streptococcus assists pathogenesis by enhancing evasion of the innate immune response
    • Sumby P, BarbianKD,Gardner DJ, Whitney AR,WeltyDM,et al. 2005. Extracellular deoxyribonuclease made by group A Streptococcus assists pathogenesis by enhancing evasion of the innate immune response. Proc. Natl. Acad. Sci. USA 102:1679-1684
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 1679-1684
    • Sumby, P.1    Barbian, K.D.2    Gardner, D.J.3    Whitney, A.R.4    Welty, D.M.5
  • 54
    • 0036900443 scopus 로고    scopus 로고
    • M types of group A streptococcal isolates submitted to the National Center for Streptococcus (Canada) from 1993 to 1999
    • Tyrrell GJ, Lovgren M, Forwick B, Hoe NP, Musser JM, Talbot JA. 2002. M types of group A streptococcal isolates submitted to the National Center for Streptococcus (Canada) from 1993 to 1999. J. Clin. Microbiol. 40:4466-4471
    • (2002) J. Clin. Microbiol. , vol.40 , pp. 4466-4471
    • Tyrrell, G.J.1    Lovgren, M.2    Forwick, B.3    Hoe, N.P.4    Musser, J.M.5    Talbot, J.A.6
  • 55
    • 33750431409 scopus 로고    scopus 로고
    • Identification and characterization of bicistronic speB and prsA gene expression in the group A Streptococcus
    • Ma Y, Bryant AE, Salmi DB, Hayes-Schroer SM,McIndoo E, et al. 2006. Identification and characterization of bicistronic speB and prsA gene expression in the group A Streptococcus. J. Bacteriol. 188:7626-7634
    • (2006) J. Bacteriol. , vol.188 , pp. 7626-7634
    • Ma, Y.1    Bryant, A.E.2    Salmi, D.B.3    Hayes-Schroer, S.M.4    McIndoo, E.5
  • 56
    • 0033042528 scopus 로고    scopus 로고
    • Extracellular cysteine protease produced by Streptococcus pyogenes participates in the pathogenesis of invasive skin infection and dissemination in mice
    • Lukomski S, Montgomery CA, Rurangirwa J, Geske RS, Barrish JP, et al. 1999. Extracellular cysteine protease produced by Streptococcus pyogenes participates in the pathogenesis of invasive skin infection and dissemination in mice. Infect. Immun. 67:1779-1788
    • (1999) Infect. Immun. , vol.67 , pp. 1779-1788
    • Lukomski, S.1    Montgomery, C.A.2    Rurangirwa, J.3    Geske, R.S.4    Barrish, J.P.5
  • 57
    • 40749113609 scopus 로고    scopus 로고
    • A chemokine-degrading extracellular protease made by group A Streptococcus alters pathogenesis by enhancing evasion of the innate immune response
    • Sumby P, Zhang S, Whitney AR, Falugi F, Grandi G, et al. 2008. A chemokine-degrading extracellular protease made by group A Streptococcus alters pathogenesis by enhancing evasion of the innate immune response. Infect. Immun. 76:978-985
    • (2008) Infect. Immun. , vol.76 , pp. 978-985
    • Sumby, P.1    Zhang, S.2    Whitney, A.R.3    Falugi, F.4    Grandi, G.5
  • 58
    • 4344601240 scopus 로고    scopus 로고
    • Plasminogen is a critical host pathogenicity factor for group A streptococcal infection
    • Sun H, Ringdahl U, Homeister JW, Fay WP, Engleberg NC, et al. 2004. Plasminogen is a critical host pathogenicity factor for group A streptococcal infection. Science 305:1283-1286
    • (2004) Science , vol.305 , pp. 1283-1286
    • Sun, H.1    Ringdahl, U.2    Homeister, J.W.3    Fay, W.P.4    Engleberg, N.C.5
  • 59
    • 0032795615 scopus 로고    scopus 로고
    • Staging of the baboon response to group A streptococci administered intramuscularly: A descriptive study of the clinical symptoms and clinical chemical response patterns
    • Taylor FB Jr, Bryant AE, Blick KE, Hack E, Jansen PM, et al. 1999. Staging of the baboon response to group A streptococci administered intramuscularly: a descriptive study of the clinical symptoms and clinical chemical response patterns. Clin. Infect. Dis. 29:167-177
    • (1999) Clin. Infect. Dis. , vol.29 , pp. 167-177
    • Taylor Jr., F.B.1    Bryant, A.E.2    Blick, K.E.3    Hack, E.4    Jansen, P.M.5
  • 60
    • 0024340460 scopus 로고
    • Severe group A streptococcal infections associated with a toxic shock-like syndrome and scarlet fever toxin
    • Stevens DL, Tanner MH, Winship J, Swarts R, Ries KM, et al. 1989. Severe group A streptococcal infections associated with a toxic shock-like syndrome and scarlet fever toxin A. N. Engl. J. Med. 321:1-7
    • (1989) A. N. Engl. J. Med. , vol.321 , pp. 1-7
    • Stevens, D.L.1    Tanner, M.H.2    Winship, J.3    Swarts, R.4    Ries, K.M.5
  • 61
    • 0141840766 scopus 로고    scopus 로고
    • Molecular genetic analysis of 675 group A Streptococcus isolates collected in a carrier study at Lackland Air Force Base, San Antonio
    • Hoe NP, Fullerton KE, Liu M, Peters JE, Gackstetter GD, et al. 2003. Molecular genetic analysis of 675 group A Streptococcus isolates collected in a carrier study at Lackland Air Force Base, San Antonio, Texas. J. Infect. Dis. 18 8:818-827
    • (2003) Texas. J. Infect. Dis. , vol.188 , pp. 818-827
    • Hoe, N.P.1    Fullerton, K.E.2    Liu, M.3    Peters, J.E.4    Gackstetter, G.D.5
  • 62
    • 0036266507 scopus 로고    scopus 로고
    • Molecular mechanisms of adhesion, colonization, and invasion of group A streptococci
    • Courtney HS, Hasty DL, Dale JB. 2002. Molecular mechanisms of adhesion, colonization, and invasion of group A streptococci. Ann. Med. 34:77-87
    • (2002) Ann. Med. , vol.34 , pp. 77-87
    • Courtney, H.S.1    Hasty, D.L.2    Dale, J.B.3
  • 63
    • 0026661424 scopus 로고
    • Protein F, afibronectin-binding protein, is an adhesin of the group A Streptococcus pyogenes
    • Hanski E, Caparon M. 1992. Protein F, a fibronectin-binding protein, is an adhesin of the group A Streptococcus pyogenes. Proc. Natl. Acad. Sci. USA 89:6172-6176
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6172-6176
    • Hanski, E.1    Caparon, M.2
  • 64
    • 44449117596 scopus 로고    scopus 로고
    • Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete
    • Gillen CM, Courtney HS, Schulze K, Rohde M, Wilson MR, et al. 2008. Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete. J. Biol. Chem. 283:6359-6366
    • (2008) J. Biol. Chem. , vol.283 , pp. 6359-6366
    • Gillen, C.M.1    Courtney, H.S.2    Schulze, K.3    Rohde, M.4    Wilson, M.R.5
  • 65
    • 0041322724 scopus 로고    scopus 로고
    • Serum opacity factor (SOF) of Streptococcus pyogenes evokesantibodies that opsonize homologous and heterologous SOF-positive serotypes of group A streptococci
    • Courtney HS, Hasty DL, Dale JB. 2003. Serum opacity factor (SOF) of Streptococcus pyogenes evokes antibodies that opsonize homologous and heterologous SOF-positive serotypes of group A streptococci. Infect. Immun. 71:5097-5103
    • (2003) Infect. Immun. , vol.71 , pp. 5097-5103
    • Courtney, H.S.1    Hasty, D.L.2    Dale, J.B.3
  • 66
    • 32344435599 scopus 로고    scopus 로고
    • Intranasal immunization with serum opacity factor (SOF) of Streptococcus pyogenes fails to protect mice against lethal mucosal challenge with a heterologous strain
    • Schulze K, Medina E, Guzman CA. 2006. Intranasal immunization with serum opacity factor (SOF) of Streptococcus pyogenes fails to protect mice against lethal mucosal challenge with a heterologous strain. Vaccine 24:1446-1450
    • (2006) Vaccine , vol.24 , pp. 1446-1450
    • Schulze, K.1    Medina, E.2    Guzman, C.A.3
  • 67
    • 27344448129 scopus 로고    scopus 로고
    • Group A Streptococcus produce piluslike structures containing protective antigens and Lancefield T antigens
    • Mora M, Bensi G, Capo S, Falugi F, Zingaretti C, et al. 2005. Group A Streptococcus produce piluslike structures containing protective antigens and Lancefield T antigens. Proc. Natl. Acad. Sci. USA 102:15641-15646
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 15641-15646
    • Mora, M.1    Bensi, G.2    Capo, S.3    Falugi, F.4    Zingaretti, C.5
  • 68
    • 33846929809 scopus 로고    scopus 로고
    • Role of streptococcal T antigens in superficial skin infection
    • Lizano S, Luo F, Bessen DE. 2007. Role of streptococcal T antigens in superficial skin infection. J. Bacteriol. 189:1426-1434
    • (2007) J. Bacteriol. , vol.189 , pp. 1426-1434
    • Lizano, S.1    Luo, F.2    Bessen, D.E.3
  • 69
    • 56749155689 scopus 로고    scopus 로고
    • Sequence variation in group A Streptococcus pili and association of pilus backbone types with Lancefield T serotypes
    • Falugi F, Zingaretti C, Pinto V, Mariani M, Amodeo L, et al. 2008. Sequence variation in group A Streptococcus pili and association of pilus backbone types with Lancefield T serotypes. J. Infect. Dis. 198:1834-1841
    • (2008) J. Infect. Dis. , vol.198 , pp. 1834-1841
    • Falugi, F.1    Zingaretti, C.2    Pinto, V.3    Mariani, M.4    Amodeo, L.5
  • 70
    • 58749093047 scopus 로고    scopus 로고
    • Preventing bacterial infections with pilus-based vaccines: The group B Streptococcus paradigm
    • Margarit I, Rinaudo CD, Galeotti CL, Maione D, Ghezzo C, et al. 2009. Preventing bacterial infections with pilus-based vaccines: the group B Streptococcus paradigm. J. Infect. Dis. 199:108-115
    • (2009) J. Infect. Dis. , vol.199 , pp. 108-115
    • Margarit, I.1    Rinaudo, C.D.2    Galeotti, C.L.3    Maione, D.4    Ghezzo, C.5
  • 71
    • 33750459365 scopus 로고    scopus 로고
    • Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2
    • Sitkiewicz I, Nagiec MJ, Sumby P, Butler SD, Cywes-Bentley C, Musser JM. 2006. Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2. Proc. Natl. Acad. Sci. USA 103:16009-16014
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16009-16014
    • Sitkiewicz, I.1    Nagiec, M.J.2    Sumby, P.3    Butler, S.D.4    Cywes-Bentley, C.5    Musser, J.M.6
  • 72
    • 32344453260 scopus 로고    scopus 로고
    • Characterization and identification of vaccine candidate proteins through analysis of the groupAStreptococcus surface proteome
    • Rodriguez-Ortega MJ, Norais N, Bensi G, Liberatori S, Capo S, et al. 2006. Characterization and identification of vaccine candidate proteins through analysis of the groupAStreptococcus surface proteome. Nat. Biotechnol. 24:191-197
    • (2006) Nat. Biotechnol. , vol.24 , pp. 191-197
    • Rodriguez-Ortega, M.J.1    Norais, N.2    Bensi, G.3    Liberatori, S.4    Capo, S.5
  • 73
    • 58149328654 scopus 로고    scopus 로고
    • Overcoming function annotation errors in the gram-positive pathogen Streptococcus suis by a proteomics-driven approach
    • Rodriguez-Ortega MJ, Luque I, Tarradas C, Barcena JA. 2008. Overcoming function annotation errors in the gram-positive pathogen Streptococcus suis by a proteomics-driven approach. BMC Genomics 9:588
    • (2008) BMC Genomics , vol.9 , pp. 588
    • Rodriguez-Ortega, M.J.1    Luque, I.2    Tarradas, C.3    Barcena, J.A.4
  • 74
    • 2942614702 scopus 로고    scopus 로고
    • Interactions with fibronectin attenuate the virulence of Streptococcus pyogenes
    • Nyberg P, Sakai T, Cho KH, Caparon MG, Fassler R, Bjorck L. 2004. Interactions with fibronectin attenuate the virulence of Streptococcus pyogenes. EMBO J. 23:2166-2174
    • (2004) EMBO J. , vol.23 , pp. 2166-2174
    • Nyberg, P.1    Sakai, T.2    Cho, K.H.3    Caparon, M.G.4    Fassler, R.5    Bjorck, L.6
  • 75
    • 21144443961 scopus 로고    scopus 로고
    • Longitudinalanalysis of the group A Streptococcus transcriptome in experimental pharyngitis in cynomolgus macaques
    • Virtaneva K, Porcella SF, Graham MR, Ireland RM, Johnson CA, et al. 2005. Longitudinal analysis of the group A Streptococcus transcriptome in experimental pharyngitis in cynomolgus macaques. Proc. Natl. Acad. Sci. USA 102:9014-9019
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 9014-9019
    • Virtaneva, K.1    Porcella, S.F.2    Graham, M.R.3    Ireland, R.M.4    Johnson, C.A.5
  • 76
    • 0030087812 scopus 로고    scopus 로고
    • Human salivary glucose analysis by high-performance ion-exchange chromatography and pulsed amperometric detection
    • Gough H, Luke GA, Beeley JA, Geddes DA. 1996. Human salivary glucose analysis by high-performance ion-exchange chromatography and pulsed amperometric detection. Arch. Oral. Biol. 41:141-145
    • (1996) Arch. Oral. Biol. , vol.41 , pp. 141-145
    • Gough, H.1    Luke, G.A.2    Beeley, J.A.3    Geddes, D.A.4
  • 77
    • 34147118421 scopus 로고    scopus 로고
    • MalE of group A Streptococcus participates in the rapid transport of maltotriose and longer maltodextrins
    • Shelburne SA 3rd, Fang H, Okorafor N, Sumby P, Sitkiewicz I, et al. 2007. MalE of group A Streptococcus participates in the rapid transport of maltotriose and longer maltodextrins. J. Bacteriol. 189:2610-2617
    • (2007) J. Bacteriol. , vol.189 , pp. 2610-2617
    • Shelburne Iii, S.A.1    Fang, H.2    Okorafor, N.3    Sumby, P.4    Sitkiewicz, I.5
  • 78
    • 40349097955 scopus 로고    scopus 로고
    • A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus
    • Shelburne SA 3rd, Keith D, Horstmann N, Sumby P, Davenport MT, et al. 2008. A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus. Proc. Natl. Acad. Sci. USA 105:1698-1703
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 1698-1703
    • Shelburne Iii, S.A.1    Keith, D.2    Horstmann, N.3    Sumby, P.4    Davenport, M.T.5
  • 79
    • 0027158446 scopus 로고
    • Role of M protein in pharyngeal colonization by group A streptococci in rats
    • Hollingshead SK, Simecka JW, Michalek SM. 1993. Role of M protein in pharyngeal colonization by group A streptococci in rats. Infect. Immun. 61:2277-2283
    • (1993) Infect. Immun. , vol.61 , pp. 2277-2283
    • Hollingshead, S.K.1    Simecka, J.W.2    Michalek, S.M.3
  • 80
    • 0032145096 scopus 로고    scopus 로고
    • Molecular analysis of the role of the group A streptococcal cysteine protease, hyaluronic acid capsule, and M protein in a murine model of human invasive soft-tissue infection
    • Ashbaugh CD, Warren HB, Carey VJ, Wessels MR. 1998. Molecular analysis of the role of the group A streptococcal cysteine protease, hyaluronic acid capsule, and M protein in a murine model of human invasive soft-tissue infection. J. Clin. Investig. 102:550-560
    • (1998) J. Clin. Investig. , vol.102 , pp. 550-560
    • Ashbaugh, C.D.1    Warren, H.B.2    Carey, V.J.3    Wessels, M.R.4
  • 81
    • 0001197006 scopus 로고
    • Current knowledge of type-specificMantigens of groupAstreptococci
    • Lancefield RC. 1962. Current knowledge of type-specificMantigens of groupAstreptococci. J. Immunol. 89:307-313
    • (1962) J. Immunol. , vol.89 , pp. 307-313
    • Lancefield, R.C.1
  • 82
    • 0017712962 scopus 로고
    • StreptococcalMprotein extracted by nonionic detergent. II. Analysis of the antibody response to the multiple antigenic determinants of the M-protein molecule
    • Fischetti VA. 1977. StreptococcalMprotein extracted by nonionic detergent. II. Analysis of the antibody response to the multiple antigenic determinants of the M-protein molecule. J. Exp. Med. 146:1108-1123
    • (1977) J. Exp. Med. , vol.146 , pp. 1108-1123
    • Fischetti, V.A.1
  • 83
    • 39149094630 scopus 로고    scopus 로고
    • Current status of group A streptococcal vaccine development
    • Dale JB. 2008. Current status of group A streptococcal vaccine development. Adv. Exp. Med. Biol. 609:53-63
    • (2008) Adv. Exp. Med. Biol. , vol.609 , pp. 53-63
    • Dale, J.B.1
  • 85
    • 28444441948 scopus 로고    scopus 로고
    • Active and passive intranasal immunizations with streptococcal surface protein C5a peptidase prevent infection of murine nasal mucosa-associated lymphoid tissue, a functional homologue of human tonsils
    • Park HS, Cleary PP. 2005. Active and passive intranasal immunizations with streptococcal surface protein C5a peptidase prevent infection of murine nasal mucosa-associated lymphoid tissue, a functional homologue of human tonsils. Infect. Immun. 73:7878-86
    • (2005) Infect. Immun. , vol.73 , pp. 7878-7886
    • Park, H.S.1    Cleary, P.P.2
  • 87
    • 0030067110 scopus 로고    scopus 로고
    • Protein SIC, a novel extracellular protein of Streptococcus pyogenes interfering with complement function
    • Akesson P, Sjoholm AG, Bjorck L. 1996. Protein SIC, a novel extracellular protein of Streptococcus pyogenes interfering with complement function. J. Biol. Chem. 271:1081-1088
    • (1996) J. Biol. Chem. , vol.271 , pp. 1081-1088
    • Akesson, P.1    Sjoholm, A.G.2    Bjorck, L.3
  • 88
    • 33847009078 scopus 로고    scopus 로고
    • The CXC chemokine MIG/CXCL9 is important in innate immunity against Streptococcus pyogenes
    • Egesten A, Eliasson M, Johansson HM, Olin AI, Morgelin M, et al. 2007. The CXC chemokine MIG/CXCL9 is important in innate immunity against Streptococcus pyogenes. J. Infect. Dis. 195:684-693
    • (2007) J. Infect. Dis. , vol.195 , pp. 684-693
    • Egesten, A.1    Eliasson, M.2    Johansson, H.M.3    Olin, A.I.4    Morgelin, M.5
  • 89
    • 0037188512 scopus 로고    scopus 로고
    • Insight into the molecular basis of pathogen abundance: Group A Streptococcus inhibitor of complement inhibits bacterial adherence and internalization into human cells
    • Hoe NP, Ireland RM, DeLeo FR, Gowen BB, Dorward DW, et al. 2002. Insight into the molecular basis of pathogen abundance: Group A Streptococcus inhibitor of complement inhibits bacterial adherence and internalization into human cells. Proc. Natl. Acad. Sci. USA 99:7646-7651
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 7646-7651
    • Hoe, N.P.1    Ireland, R.M.2    De Leo, F.R.3    Gowen, B.B.4    Dorward, D.W.5
  • 90
    • 32944465559 scopus 로고    scopus 로고
    • DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps
    • Buchanan JT, Simpson AJ, Aziz RK, Liu GY, Kristian SA, et al. 2006. DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps. Curr. Biol. 16:396-400
    • (2006) Curr. Biol. , vol.16 , pp. 396-400
    • Buchanan, J.T.1    Simpson, A.J.2    Aziz, R.K.3    Liu, G.Y.4    Kristian, S.A.5
  • 91
    • 0030950679 scopus 로고    scopus 로고
    • Intracellular reservoir of Streptococcus pyogenes in vivo: A possible explanation for recurrent pharyngotonsillitis
    • Osterlund A, Popa R, Nikkila T, Scheynius A, Engstrand L. 1997. Intracellular reservoir of Streptococcus pyogenes in vivo: a possible explanation for recurrent pharyngotonsillitis. Laryngoscope 107:640-647
    • (1997) Laryngoscope , vol.107 , pp. 640-647
    • Osterlund, A.1    Popa, R.2    Nikkila, T.3    Scheynius, A.4    Engstrand, L.5
  • 92
    • 58149309761 scopus 로고    scopus 로고
    • Intracelluar invasion by Streptococcus pyogenes: Invasins, host receptors, and relevance to human disease
    • ed. V Fischetti, RP Novick, JJ Ferretti, DA Portnoy, JI Rodd Washington, DC: ASM
    • Wang B, Cue D, Cleary PP. 2006. Intracelluar invasion by Streptococcus pyogenes: invasins, host receptors, and relevance to human disease. In Gram-Positive Pathogens, ed. V Fischetti, RP Novick, JJ Ferretti, DA Portnoy, JI Rodd, pp. 29-36.Washington, DC: ASM
    • (2006) Gram-Positive Pathogens , pp. 29-36
    • Wang, B.1    Cue, D.2    Cleary, P.P.3
  • 93
    • 33144467086 scopus 로고    scopus 로고
    • Streptococcal modulation of cellular invasion via TGF-?1 signaling
    • Wang B, Li S, Southern PJ, Cleary PP. 2006. Streptococcal modulation of cellular invasion via TGF-?1 signaling. Proc. Natl. Acad. Sci. USA 103:2380-85
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2380-2385
    • Wang, B.1    Li, S.2    Southern, P.J.3    Cleary, P.P.4
  • 94
    • 2942618331 scopus 로고    scopus 로고
    • SpeB modulates fibronectindependent internalization of Streptococcus pyogenes by efficient proteolysis of cell-wall-anchored protein F1
    • Nyberg P, Rasmussen M, Von Pawel-Rammingen U, Bjorck L. 2004. SpeB modulates fibronectindependent internalization of Streptococcus pyogenes by efficient proteolysis of cell-wall-anchored protein F1. Microbiology 150:1559-1569
    • (2004) Microbiology , vol.150 , pp. 1559-1569
    • Nyberg, P.1    Rasmussen, M.2    Von Pawel-Rammingen, U.3    Bjorck, L.4
  • 97
    • 33749362962 scopus 로고    scopus 로고
    • A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues
    • Hidalgo-Grass C, Mishalian I, Dan-Goor M, Belotserkovsky I, Eran Y, et al. 2006. A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues. EMBO J. 25:4628-4637
    • (2006) EMBO J. , vol.25 , pp. 4628-4637
    • Hidalgo-Grass, C.1    Mishalian, I.2    Dan-Goor, M.3    Belotserkovsky, I.4    Eran, Y.5
  • 98
    • 55849125399 scopus 로고    scopus 로고
    • Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein
    • Soehnlein O, Oehmcke S, Ma X, Rothfuchs AG, Frithiof R, et al. 2008. Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein. Eur. Respir. J. 32:405-412
    • (2008) Eur. Respir. J. , vol.32 , pp. 405-412
    • Soehnlein, O.1    Oehmcke, S.2    Ma, X.3    Rothfuchs, A.G.4    Frithiof, R.5
  • 99
    • 0035657925 scopus 로고    scopus 로고
    • Evasion of human innate and acquired immunity by a bacterial homolog of CD11b that inhibits opsonophagocytosis
    • Lei B, DeLeo FR, HoeNP, Graham MR,Mackie SM, et al. 2001. Evasion of human innate and acquired immunity by a bacterial homolog of CD11b that inhibits opsonophagocytosis. Nat. Med. 7:1298-1305
    • (2001) Nat. Med. , vol.7 , pp. 1298-1305
    • Lei, B.1    De Leo, F.R.2    Hoe, N.P.3    Graham, M.R.4    MacKie, S.M.5
  • 100
    • 0037007214 scopus 로고    scopus 로고
    • IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G
    • von Pawel-Rammingen U, Johansson BP, Bjorck L. 2002. IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G. EMBO J. 21:1607-1615
    • (2002) EMBO J. , vol.21 , pp. 1607-1615
    • Von Pawel-Rammingen, U.1    Johansson, B.P.2    Bjorck, L.3
  • 101
    • 29644438454 scopus 로고    scopus 로고
    • IdeS, a highly specific immunoglobulin G (IgG)-cleaving enzyme from Streptococcus pyogenes, is inhibited by specific IgG antibodies generated during infection
    • Akesson P Moritz L Truedsson M Christensson B Von Pawel-Rammingen U 2006. IdeS, a highly specific immunoglobulin G (IgG)-cleaving enzyme from Streptococcus pyogenes, is inhibited by specific IgG antibodies generated during infection. Infect. Immun. 74. 497-503.
    • (2006) Infect. Immun. , vol.74 , pp. 497-503
    • Akesson, P.1    Moritz, L.2    Truedsson, M.3    Christensson, B.4    Von Pawel-Rammingen, U.5
  • 102
    • 42949106144 scopus 로고    scopus 로고
    • The intrinsic immunoglobulin G endopeptidase activity of streptococcal Mac-2 proteins implies a unique role for the enzymatically impaired Mac-2 protein of M28 serotype strains
    • Soderberg JJ, Engstrom P, von Pawel-Rammingen U. 2008. The intrinsic immunoglobulin G endopeptidase activity of streptococcal Mac-2 proteins implies a unique role for the enzymatically impaired Mac-2 protein of M28 serotype strains. Infect. Immun. 76:2183-2188
    • (2008) Infect. Immun. , vol.76 , pp. 2183-2188
    • Soderberg, J.J.1    Engstrom, P.2    Von Pawel-Rammingen, U.3
  • 103
    • 35348848012 scopus 로고    scopus 로고
    • Blocking of experimental arthritis by cleavage of IgG antibodies in vivo
    • Nandakumar KS, Johansson BP, Bjorck L, Holmdahl R. 2007. Blocking of experimental arthritis by cleavage of IgG antibodies in vivo. Arthritis Rheum. 56:3253-3260
    • (2007) Arthritis Rheum. , vol.56 , pp. 3253-3260
    • Nandakumar, K.S.1    Johansson, B.P.2    Bjorck, L.3    Holmdahl, R.4
  • 105
    • 34447275428 scopus 로고
    • Esterase in extracellular concentrates of group A streptococci and the homologous antibody
    • Stock AH, Uriel J, Grabar P. 1961. Esterase in extracellular concentrates of group A streptococci and the homologous antibody. Nature 192:434-435
    • (1961) Nature , vol.192 , pp. 434-435
    • Stock, A.H.1    Uriel, J.2    Grabar, P.3
  • 106
    • 34447280868 scopus 로고    scopus 로고
    • Active and passive immunizations with the streptococcal esterase Sse protect mice against subcutaneous infection with group A streptococci
    • Liu M, Zhu H, Zhang J, Lei B. 2007. Active and passive immunizations with the streptococcal esterase Sse protect mice against subcutaneous infection with group A streptococci. Infect. Immun. 75:3651-3657
    • (2007) Infect. Immun. , vol.75 , pp. 3651-3657
    • Liu, M.1    Zhu, H.2    Zhang, J.3    Lei, B.4
  • 108
    • 54449083249 scopus 로고    scopus 로고
    • Effects of streptococcal pyrogenic exotoxin B on pathogenesis of Streptococcus pyogenes
    • Chiang-Ni C,Wu JJ. 2008. Effects of streptococcal pyrogenic exotoxin B on pathogenesis of Streptococcus pyogenes. J. Formos. Med. Assoc. 107:677-685
    • (2008) J. Formos. Med. Assoc. , vol.107 , pp. 677-685
    • Chiang-Ni, C.1    Wu, J.J.2
  • 109
    • 10244261522 scopus 로고    scopus 로고
    • Activation of a 66-kDa human endothelial cell matrix metalloprotease by Streptococcus pyogenes extracellular cysteine protease
    • Burns EH Jr, Marciel AM, Musser JM. 1996. Activation of a 66-kDa human endothelial cell matrix metalloprotease by Streptococcus pyogenes extracellular cysteine protease. Infect. Immun. 64:4744-4750
    • (1996) Infect. Immun. , vol.64 , pp. 4744-4750
    • Burns Jr., E.H.1    Marciel, A.M.2    Musser, J.M.3
  • 111
    • 3342981167 scopus 로고    scopus 로고
    • Proapoptotic effect of proteolytic activation of matrix metalloproteinases by Streptococcus pyogenes thiol proteinase (Streptococcus pyrogenic exotoxin B)
    • Tamura F, Nakagawa R, Akuta T, Okamoto S, Hamada S, et al. 2004. Proapoptotic effect of proteolytic activation of matrix metalloproteinases by Streptococcus pyogenes thiol proteinase (Streptococcus pyrogenic exotoxin B). Infect. Immun. 72:4836-4847
    • (2004) Infect. Immun. , vol.72 , pp. 4836-4847
    • Tamura, F.1    Nakagawa, R.2    Akuta, T.3    Okamoto, S.4    Hamada, S.5
  • 112
    • 1642333235 scopus 로고    scopus 로고
    • Mprotein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage
    • Herwald H, Cramer H, Morgelin M, Russell W, Sollenberg U, et al. 2004.Mprotein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage. Cell 116:367-379
    • (2004) Cell , vol.116 , pp. 367-379
    • Herwald, H.1    Cramer, H.2    Morgelin, M.3    Russell, W.4    Sollenberg, U.5
  • 113
    • 48749114201 scopus 로고    scopus 로고
    • M protein-mediated plasminogen binding is essential for the virulence of an invasive Streptococcus pyogenes isolate
    • Sanderson-Smith ML, Dinkla K, Cole JN, Cork AJ, Maamary PG, et al. 2008. M protein-mediated plasminogen binding is essential for the virulence of an invasive Streptococcus pyogenes isolate. FASEB J. 22:2715-2722
    • (2008) FASEB J. , vol.22 , pp. 2715-2722
    • Sanderson-Smith, M.L.1    Dinkla, K.2    Cole, J.N.3    Cork, A.J.4    Maamary, P.G.5
  • 114
    • 0041440157 scopus 로고    scopus 로고
    • Plasminogen enhances virulence of group A streptococci by streptokinase-dependent and streptokinase-independent mechanisms
    • Khil J, Im M, Heath A, Ringdahl U, Mundada L, et al. 2003. Plasminogen enhances virulence of group A streptococci by streptokinase-dependent and streptokinase-independent mechanisms. J. Infect. Dis. 188:497-505
    • (2003) J. Infect. Dis. , vol.188 , pp. 497-505
    • Khil, J.1    Im, M.2    Heath, A.3    Ringdahl, U.4    Mundada, L.5
  • 115
    • 27744445987 scopus 로고    scopus 로고
    • Increased expression of the ska gene in emm49-genotyped Streptococcus pyogenes strains isolated from patients with severe invasive streptococcal infections
    • Ikebe T, Endoh M, Watanabe H. 2005. Increased expression of the ska gene in emm49-genotyped Streptococcus pyogenes strains isolated from patients with severe invasive streptococcal infections. Jpn. J. Infect. Dis. 58:272-275 (Pubitemid 41614736)
    • (2005) Japanese Journal of Infectious Diseases , vol.58 , Issue.5 , pp. 272-275
    • Ikebe, T.1    Endoh, M.2    Watanabe, H.3
  • 116
    • 9144271096 scopus 로고    scopus 로고
    • Plasminogen binding by group A streptococcal isolates from a region of hyperendemicity for streptococcal skin infection and a high incidence of invasive infection
    • McKay FC, McArthur JD, Sanderson-Smith ML, Gardam S, Currie BJ, et al. 2004. Plasminogen binding by group A streptococcal isolates from a region of hyperendemicity for streptococcal skin infection and a high incidence of invasive infection. Infect. Immun. 72:364-370
    • (2004) Infect. Immun. , vol.72 , pp. 364-370
    • McKay, F.C.1    McArthur, J.D.2    Sanderson-Smith, M.L.3    Gardam, S.4    Currie, B.J.5
  • 117
    • 51349138787 scopus 로고    scopus 로고
    • Allelic variants of streptokinase from Streptococcus pyogenes display functional differences in plasminogen activation
    • McArthur JD McKay FC Ramachandran V Shyam P Cork AJ et al. 2008 Allelic variants of streptokinase from Streptococcus pyogenes display functional differences in plasminogen activation, FASEB J. 22. 3146-3153
    • (2008) FASEB J. , vol.22 , pp. 3146-3153
    • McArthur, J.D.1    McKay, F.C.2    Ramachandran, V.3    Shyam, P.4    Cork, A.J.5
  • 118
    • 23944488853 scopus 로고    scopus 로고
    • Specific C-terminal cleavage and inactivation of interleukin-8 by invasive disease isolates of Streptococcus pyogenes
    • Edwards RJ,TaylorGW,Ferguson M, Murray S, Rendell N, et al. 2005. Specific C-terminal cleavage and inactivation of interleukin-8 by invasive disease isolates of Streptococcus pyogenes. J. Infect. Dis. 192:783-790
    • (2005) J. Infect. Dis. , vol.192 , pp. 783-790
    • Edwards, R.J.1    Taylor, G.W.2    Ferguson, M.3    Murray, S.4    Rendell, N.5
  • 119
    • 33645776051 scopus 로고    scopus 로고
    • Genome-wide analysis of group A streptococci reveals a mutation that modulates global phenotype and disease specificity
    • Sumby P, Whitney AR, Graviss EA, DeLeo FR, Musser JM. 2006. Genome-wide analysis of group A streptococci reveals a mutation that modulates global phenotype and disease specificity. PLoS Pathog. 2:e5
    • (2006) PLoS Pathog. , vol.2
    • Sumby, P.1    Whitney, A.R.2    Graviss, E.A.3    De Leo, F.R.4    Musser, J.M.5
  • 120
    • 0035313287 scopus 로고    scopus 로고
    • Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infection
    • Engleberg NC, Heath A, Miller A, Rivera C, DiRita VJ. 2001. Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infection. J. Infect. Dis. 183:1043-1054
    • (2001) J. Infect. Dis. , vol.183 , pp. 1043-1054
    • Engleberg, N.C.1    Heath, A.2    Miller, A.3    Rivera, C.4    Di Rita, V.J.5
  • 121
    • 53649092162 scopus 로고    scopus 로고
    • TrxR, a new CovR-repressed response regulator that activates the Mga virulence regulon in group A Streptococcus
    • Leday TV, Gold KM, Kinkel TL, Roberts SA, Scott JR, McIver KS. 2008. TrxR, a new CovR-repressed response regulator that activates the Mga virulence regulon in group A Streptococcus. Infect. Immun. 76:4659-4668
    • (2008) Infect. Immun. , vol.76 , pp. 4659-4668
    • Leday, T.V.1    Gold, K.M.2    Kinkel, T.L.3    Roberts, S.A.4    Scott, J.R.5    McIver, K.S.6
  • 122
    • 2942511333 scopus 로고    scopus 로고
    • CovS inactivates CovR and is required for growth under conditions of general stress in Streptococcus pyogenes
    • Dalton TL, Scott JR. 2004. CovS inactivates CovR and is required for growth under conditions of general stress in Streptococcus pyogenes. J. Bacteriol. 186:3928-3937
    • (2004) J. Bacteriol. , vol.186 , pp. 3928-3937
    • Dalton, T.L.1    Scott, J.R.2
  • 124
    • 36549029160 scopus 로고    scopus 로고
    • RivR and the smallRNARivX: The missing links betweenhe CovRregulatory cascade and the Mga regulon
    • Roberts SA, Scott JR. 2007. RivR and the smallRNARivX: the missing links between theCovRregulatory cascade and the Mga regulon. Mol. Microbiol. 66:1506-1522
    • (2007) Mol. Microbiol. , vol.66 , pp. 1506-1522
    • Roberts, S.A.1    Scott, J.R.2
  • 125
    • 0037770195 scopus 로고    scopus 로고
    • Biology and pathogenesis of thrombosis and procoagulant activity in invasive infections caused by group A streptococci and Clostridium perfringens
    • Bryant AE. 2003. Biology and pathogenesis of thrombosis and procoagulant activity in invasive infections caused by group A streptococci and Clostridium perfringens. Clin. Microbiol. Rev. 16:451-462
    • (2003) Clin. Microbiol. Rev. , vol.16 , pp. 451-462
    • Bryant, A.E.1
  • 126
    • 60849087371 scopus 로고    scopus 로고
    • Reduced thrombin generation increases host susceptibility to group A streptococcal infection
    • Sun H,Wang X, Degen JL, Ginsburg D. 2009. Reduced thrombin generation increases host susceptibility to group A streptococcal infection. Blood 113:1358-1364
    • (2009) Blood , vol.113 , pp. 1358-1364
    • Sun, H.1    Wang, X.2    Degen, J.L.3    Ginsburg, D.4
  • 127
    • 34547909609 scopus 로고    scopus 로고
    • Severe streptococcal infection is associated with M protein-induced platelet activation and thrombus formation
    • Shannon O, Hertzen E, Norrby-Teglund A, Morgelin M, Sjobring U, Bjorck L. 2007. Severe streptococcal infection is associated with M protein-induced platelet activation and thrombus formation. Mol. Microbiol. 65:1147-1157
    • (2007) Mol. Microbiol. , vol.65 , pp. 1147-1157
    • Shannon, O.1    Hertzen, E.2    Norrby-Teglund, A.3    Morgelin, M.4    Sjobring, U.5    Bjorck, L.6
  • 129
    • 40449131624 scopus 로고    scopus 로고
    • Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence
    • McNamara C, Zinkernagel AS, Macheboeuf P, Cunningham MW, Nizet V, Ghosh P. 2008. Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence. Science 319:1405-1408
    • (2008) Science , vol.319 , pp. 1405-1408
    • McNamara, C.1    Zinkernagel, A.S.2    MacHeboeuf, P.3    Cunningham, M.W.4    Nizet, V.5    Ghosh, P.6
  • 130
    • 0032508547 scopus 로고    scopus 로고
    • Crystal structure of the catalytic domain of human plasmin complexed with streptokinase
    • Wang X, Lin X, Loy JA, Tang J, Zhang XC. 1998. Crystal structure of the catalytic domain of human plasmin complexed with streptokinase. Science 281:1662-1665 (Pubitemid 128725547)
    • (1998) Science , vol.281 , Issue.5383 , pp. 1662-1665
    • Wang, X.1    Lin, X.2    Loy, J.A.3    Tang, J.4    Zhang, X.C.5
  • 131
    • 0037108912 scopus 로고    scopus 로고
    • Virulence control in group A Streptococcus by a two-component gene regulatory system: Global expression profiling and in vivo infection modeling
    • Graham MR, Smoot LM, Migliaccio CA, Virtaneva K, Sturdevant DE, et al. 2002. Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling. Proc. Natl. Acad. Sci. USA 99:13855-13860
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13855-13860
    • Graham, M.R.1    Smoot, L.M.2    Migliaccio, C.A.3    Virtaneva, K.4    Sturdevant, D.E.5
  • 132
    • 30744463313 scopus 로고    scopus 로고
    • Regulation of SpeB in Streptococcus pyogenes by pH and NaCl: A model for in vivo gene expression
    • Loughman JA, Caparon M. 2006. Regulation of SpeB in Streptococcus pyogenes by pH and NaCl: a model for in vivo gene expression. J. Bacteriol. 188:399-408
    • (2006) J. Bacteriol. , vol.188 , pp. 399-408
    • Loughman, J.A.1    Caparon, M.2
  • 133
    • 0037312503 scopus 로고    scopus 로고
    • Selective modulation of superantigen-induced responses by streptococcal cysteine protease
    • Kansal RG, Nizet V, Jeng A, Chuang WJ, Kotb M. 2003. Selective modulation of superantigen-induced responses by streptococcal cysteine protease. J. Infect. Dis. 187:398-407
    • (2003) J. Infect. Dis. , vol.187 , pp. 398-407
    • Kansal, R.G.1    Nizet, V.2    Jeng, A.3    Chuang, W.J.4    Kotb, M.5
  • 134
    • 0036153610 scopus 로고    scopus 로고
    • Rgg influences the expression of multiple regulatory loci to coregulate virulence factor expression in Streptococcus pyogenes
    • Chaussee MS, Sylva GL, Sturdevant DE, Smoot LM, Graham MR, et al. 2002. Rgg influences the expression of multiple regulatory loci to coregulate virulence factor expression in Streptococcus pyogenes. Infect. Immun. 70:762-770
    • (2002) Infect. Immun. , vol.70 , pp. 762-770
    • Chaussee, M.S.1    Sylva, G.L.2    Sturdevant, D.E.3    Smoot, L.M.4    Graham, M.R.5
  • 135
    • 34547693093 scopus 로고    scopus 로고
    • DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection
    • Walker MJ, Hollands A, Sanderson-Smith ML, Cole JN, Kirk JK, et al. 2007. DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection. Nat. Med. 13:981-985
    • (2007) Nat. Med. , vol.13 , pp. 981-985
    • Walker, M.J.1    Hollands, A.2    Sanderson-Smith, M.L.3    Cole, J.N.4    Kirk, J.K.5
  • 136
  • 137
    • 58149354503 scopus 로고    scopus 로고
    • A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence
    • Hollands A, Aziz RK, Kansal R, Kotb M, Nizet V, Walker MJ. 2008. A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence. PLoS ONE 3:e4102
    • (2008) PLoS ONE , vol.3
    • Hollands, A.1    Aziz, R.K.2    Kansal, R.3    Kotb, M.4    Nizet, V.5    Walker, M.J.6
  • 139
    • 0034926023 scopus 로고    scopus 로고
    • Reciprocal, temporal expression of SpeA and SpeB by invasive M1T1 group A streptococcal isolates in vivo
    • Kazmi SU, Kansal R, Aziz RK, Hooshdaran M, Norrby-Teglund A, et al. 2001. Reciprocal, temporal expression of SpeA and SpeB by invasive M1T1 group A streptococcal isolates in vivo. Infect. Immun. 69:4988-4995
    • (2001) Infect. Immun. , vol.69 , pp. 4988-4995
    • Kazmi, S.U.1    Kansal, R.2    Aziz, R.K.3    Hooshdaran, M.4    Norrby-Teglund, A.5
  • 140
    • 44649110098 scopus 로고    scopus 로고
    • Inter-and intraserotypic variation in the Streptococcus pyogenes Rgg regulon
    • Dmitriev AV, McDowell EJ, Chaussee MS. 2008. Inter-and intraserotypic variation in the Streptococcus pyogenes Rgg regulon. FEMS Microbiol. Lett. 284:43-51
    • (2008) FEMS Microbiol. Lett. , vol.284 , pp. 43-51
    • Dmitriev, A.V.1    McDowell, E.J.2    Chaussee, M.S.3
  • 142
    • 12144289327 scopus 로고    scopus 로고
    • Low antibody levels against cell wall-attached proteins of Streptococcus pyogenes predispose for severe invasive disease
    • Akesson P, Rasmussen M, Mascini E, von Pawel-Rammingen U, Janulczyk R, et al. 2004. Low antibody levels against cell wall-attached proteins of Streptococcus pyogenes predispose for severe invasive disease. J. Infect. Dis. 189:797-804
    • (2004) J. Infect. Dis. , vol.189 , pp. 797-804
    • Akesson, P.1    Rasmussen, M.2    Mascini, E.3    Von Pawel-Rammingen, U.4    Janulczyk, R.5
  • 143
    • 0033040119 scopus 로고    scopus 로고
    • Risk factors in the pathogenesis of invasive group A streptococcal infections: Role of protective humoral immunity
    • Basma H, Norrby-Teglund A, Guedez Y, McGeer A, Low DE, et al. 1999. Risk factors in the pathogenesis of invasive group A streptococcal infections: role of protective humoral immunity. Infect. Immun. 67:1871-1877
    • (1999) Infect. Immun. , vol.67 , pp. 1871-1877
    • Basma, H.1    Norrby-Teglund, A.2    Guedez, Y.3    McGeer, A.4    Low, D.E.5
  • 144
    • 34247851111 scopus 로고    scopus 로고
    • Dynamics of the immune response against extracellular products of group A streptococci during infection
    • Maripuu L, Eriksson A, Eriksson B, Pauksen K, Holm S, Norgren M. 2007. Dynamics of the immune response against extracellular products of group A streptococci during infection. Clin. Vaccine Immunol. 14:44-51
    • (2007) Clin. Vaccine Immunol. , vol.14 , pp. 44-51
    • Maripuu, L.1    Eriksson, A.2    Eriksson, B.3    Pauksen, K.4    Holm, S.5    Norgren, M.6
  • 145
    • 0036908653 scopus 로고    scopus 로고
    • An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections
    • Kotb M, Norrby-Teglund A, McGeer A, El-Sherbini H, Dorak MT, et al. 2002. An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections. Nat. Med. 8:1398-1404
    • (2002) Nat. Med. , vol.8 , pp. 1398-1404
    • Kotb, M.1    Norrby-Teglund, A.2    McGeer, A.3    El-Sherbini, H.4    Dorak, M.T.5
  • 146
    • 0035479183 scopus 로고    scopus 로고
    • Evidence for superantigen involvement in severe group A streptococcal tissue infections
    • Norrby-Teglund A, Thulin P, Gan BS, Kotb M, McGeer A, et al. 2001. Evidence for superantigen involvement in severe group A streptococcal tissue infections. J. Infect. Dis. 184:853-860
    • (2001) J. Infect. Dis. , vol.184 , pp. 853-860
    • Norrby-Teglund, A.1    Thulin, P.2    Gan, B.S.3    Kotb, M.4    McGeer, A.5
  • 147
    • 56849100940 scopus 로고    scopus 로고
    • Vaccine based on a ubiquitous cysteinyl protease and streptococcal pyrogenic exotoxin A protects against Streptococcus pyogenes sepsis and toxic shock
    • Ulrich RG. 2008. Vaccine based on a ubiquitous cysteinyl protease and streptococcal pyrogenic exotoxin A protects against Streptococcus pyogenes sepsis and toxic shock. J. Immune-Based Ther. Vaccines 6:8
    • (2008) J. Immune-Based Ther. Vaccines , vol.6 , pp. 8
    • Ulrich, R.G.1
  • 149
    • 34548385636 scopus 로고    scopus 로고
    • Surveillance for hospital outbreaks of invasive group A streptococcal infections in Ontario, Canada, 1992 to 2000
    • Daneman N, Green KA, Low DE, Simor AE,Willey B, et al. 2007. Surveillance for hospital outbreaks of invasive group A streptococcal infections in Ontario, Canada, 1992 to 2000. Ann. Intern. Med. 147:234-241
    • (2007) Ann. Intern. Med. , vol.147 , pp. 234-241
    • Daneman, N.1    Green, K.A.2    Low, D.E.3    Simor, A.E.4    Willey, B.5
  • 150
    • 17044452732 scopus 로고    scopus 로고
    • Invasive group A streptococcal disease in children and association with varicella-zoster virus infection
    • Ontario Group A Streptococcal Study Group
    • Laupland KB, Davies HD, Low DE, Schwartz B, Green K, McGeer A. 2000. Invasive group A streptococcal disease in children and association with varicella-zoster virus infection. Ontario Group A Streptococcal Study Group. Pediatrics 105:E60
    • (2000) Pediatrics , vol.105
    • Laupland, K.B.1    Davies, H.D.2    Low, D.E.3    Schwartz, B.4    Green, K.5    McGeer, A.6


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