Effects of delayed and extended antioxidant treatment on acute acoustic trauma

Free Radical Research

Volumn 45, Issue 10, 2011, Pages 1162-1172

  Choi, Chul Hee ^a   Chen, Kejian ^b   Du, Xiaoping ^c   Floyd, Robert A ^d,e   Kopke, Richard D ^c,d,f  

^a Catholic University of Daegu   (South Korea)

^b NAVAL MEDICAL CENTER SAN DIEGO   (United States)

^c HOUGH EAR INSTITUTE   (United States)

^d OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^e UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

4 hydroxy 2 nonenal (4 HNE); Acetyl L carnitine (ALCAR); Antioxidant drugs; Auditory brainstem response (ABR); Hearing loss; Hydroxylated alpha tert butylnitrone (4 OHPBN); N acetyl L cysteine (NAC); Nitrotyrosine (NT); Outer hair cell loss

Indexed keywords

ACETYLCYSTEINE; LEVACECARNINE; N TERT BUTYL ALPHA PHENYLNITRONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL COUNT; CELL LOSS; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DRUG EFFECT; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; HAIR CELL; LOW FREQUENCY NOISE; NOISE INJURY; NONHUMAN; OXIDATIVE STRESS; TREATMENT DURATION;

ACOUSTIC STIMULATION; ANIMALS; ANTIOXIDANTS; CHINCHILLA; DRUG ADMINISTRATION SCHEDULE; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FEMALE; HAIR CELLS, AUDITORY, OUTER; HEARING LOSS, NOISE-INDUCED; IMMUNOHISTOCHEMISTRY; NOISE; OXIDATIVE STRESS;

EID: 80052700372     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2011.605360     Document Type: Article

References (34)

1. Kotake Y, Sang H, Miyajima T, Wallis GL. Inhibition of NFkappaB, iNOS mRNA, COX2 mRNA, and COX catalytic activity by phenyl-N-tert-butylnitrone (PBN). Biochem Biophys Acta 1998;1448:77-84. (Pubitemid 28526622)
2. Kopke RD, Bielefeld E, Liu J, Zheng J, Jackson R, Henderson D, Coleman JK. Prevention of impulse noise-induced hearing loss with antioxidants. Acta Otolaryngol 2005;125:235-243. (Pubitemid 40477189)
3. Kopke RD, Coleman JK, Liu J, Campbell KC, Riffenburgh RH. Candidate's thesis: enhancing intrinsic cochlear stress defenses to reduce noise-induced hearing loss. Laryngoscope 2002;112:1515-1532. (Pubitemid 34977550)
4. Kopke RD, Jackson RL, Coleman JK, Liu J, Bielefeld EC, Balough BJ. NAC for noise: From the bench top to the clinic. Hearing Res 2007;226:114-125. (Pubitemid 46437291)
5. Kopke RD, Weisskopf PA, Boone JL, Jackson RL, Wester DC, Hoffer ME, et al. Reduction of noise-induced hearing loss using L-NAC and salicylate in the chinchilla. Hearing Res 2000;149:138-146.
6. Choi CH, Chen K, Vasquez-Weldon A, Jackson RL, Floyd, RA, Kopke RD. Effectiveness of 4-OHPBN alone and in combination with other antioxidant drugs in the treatment of acute acoustic trauma in chinchilla. Free Radic Biol Med 2008;44:1772-784.
7. Hagen TM, Ingersoll RT, Wehr CM, Lykkesfeldt J, Vinarsky V, Bartholomew JC, et al. Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. Proc Natl Acad Sci USA 1998;95:9562-9566. (Pubitemid 28506271)
8. Gadaleta MN, Cormio A, Pesce V, Lezza AM, Cantatore P. Aging and mitochondria. Biochimie 1998;80:863-870.
9. Seidman M, Van de Water TR. Pharmacological manipulation of the inner ear. ENT Journal 2003;82:276-288.
10. Coleman JKM, Kopke RD, Liu J, Ge X, Harper EA, Jones GE, et al. Pharmacological rescue of noise induced hearing loss using N-acetylcysteine and acetyl-L-carnitine. Hearing Res 2007;226:104-113. (Pubitemid 46428031)
11. Yamane H, Nakai Y, Takayama M, Konishi K, Iguchi H, Nakagawa T, et al. The emergence of free radicals after acoustic trauma and strial blood fl ow. Acta Otolaryngol Suppl 1995;519:87-92.
12. Ohlemiller KK, Dugan LL. Elevation of reactive oxygen species following ischemia-reperfusion in mouse cochlea observed in vivo. Audiol Neurootol 1999;4:219-228. (Pubitemid 29366434)
13. Ohlemiller KK, Wright JS, Dugan LL. Early elevation of cochlear reactive oxygen species following noise exposure. Audiol Neurootol 1999;4:229-236. (Pubitemid 29366435)
14. Yamashita D, Jiang HY, Schacht J, Miller JM. Delayed production of free radicals following noise exposure. Brain Res 2004;1019:201-209. (Pubitemid 39078625)
15. Yamashita D, Jiang HY, Le Prell CG, Schacht J, Miller JM. Post-exposure treatment attenuates noise-induced hearing loss. J Neurosci 2005;134:633-642. (Pubitemid 41111790)
16. Greenwood DD. A cochlear frequency-position function for several species-29 years later. J Acoust Soc Am 1990;87: 2592-2605. (Pubitemid 20289735)
17. Eldredge DH, Miller JD, Bohne BA. A frequency-position map for the chinchilla cochlea. J Acoust Soc Am 1981;69: 1091-1095. (Pubitemid 11076329)
18. Harding GW, Bohne BA, Ahmad M. DPOAE level shifts and ABR threshold shifts compared to detailed analysis of histopathological damage from noise. Hearing Res 2002;174: 158-171. (Pubitemid 35305043)
19. Cassandro E, Sequino L, Mondola P, Attanasio G, Barbara M, Filipo, R. Effect of superoxide dismutase and allopurinol on impulse noise-exposed guinea pigs-electrophysiological and biochemical study. Acta Otolaryngol 2003;123:802-807. (Pubitemid 37222694)
20. Karlida T, Yal ç in S, Ozt ü rk A, Ust ü nda B, G ök U, Kaygusuz I, Susaman N. The role of free oxygen radicals in noise induced hearing loss: effects of melatonin and methylprednisolone. Auris Nasus Larynx 2002;29:147-152. (Pubitemid 34230365)
21. West JD, Marnett LJ. Alterations in gene expression induced by the lipid peroxidation product, 4-hydroxy-2-nonenal. Chem Res Toxicol 2005;18:1642-1653. (Pubitemid 43257745)
22. Ohshima H, Friesen M, Brouet I, Bartsch H. Nitrotyrosine as a new marker for endogenous nitrosation and nitration of proteins. Food Chem Toxicol 1990;28:647-652.
23. Weaver CV, Liu SP, Lu JF, Lin BS. The effects of benzene exposure on apoptosis in epithelial lung cells: localization by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL) and the immunocytochemical localization of apoptosis-related gene products. Cell Biol Toxicol 2007;23:201-220. (Pubitemid 46902604)
24. Floyd RA, Kopke RD, Choi C-H, Foster SB, Doblas S, Towner RA. Nitrons as therapeutics. Free Radic Biol Med 2008;45:1361-1374.
25. Henderson D, Spongr V, Subramanian M, Campo P. Anatomical effects of impact noise. Hearing Res 1994;76: 101-117. (Pubitemid 24190336)
26. Shigenaga MK, Hagen TM, Ames BN. Oxidative damage and mitochondrial decay in aging. Proc Natl Acad Sci USA 1994;91:10771-10778. (Pubitemid 24349567)
27. Fischel-Ghodsian N, Kopke RD, Ge X. Mitochondrial dysfunction in hearing loss. Mitochondrion 2004;4:675-694. (Pubitemid 39646814)
28. Dhitavat S, Ortiz D, Rogers E, Rivera E, Shea TB. Folate, vitamin E, and acetyl-L-carnitine provide synergistic protection against oxidative stress resulting from exposure of human neuroblastoma cells to amyloidbeta. Brain Res 2005;1061: 114-117. (Pubitemid 41587919)
29. Le Prell CG, Hughes LF, Miller JM. Free radical scavengers vitamins A, C, and E plus magnesium reduce noise trauma. Free Radic Biol Med 2007;42:1454-1463. (Pubitemid 46467279)
30. Yamasoba T, Schacht J, Shoji F, Miller JM. Attenuation of cochlear damage from noise trauma by an iron chelator, a free radical scavenger and glial cell line-derived neurotrophic factor in vivo. Brain Res 1999;815:317-325. (Pubitemid 29225278)
31. Liu, Z. Experimental study on the mechanism of free radical in blast trauma induced hearing loss. Chin J Otorhinolaryngol 1992;27:24-26.
32. Ohinata Y, Yamasoba T, Schacht J, Miller JM. Glutathione limits noise-induced hearing loss. Hear Res 2000;146:28-34. (Pubitemid 30458860)
33. Kujawa SG, Liberman MC. Acceleration of age-related hearing loss by early noise exposure: evidence of a misspent youth. J Nurosci 2006;26:2115-2123.
34. Du X, Choi C-H, Chen K, Cheng W, Floyd RA, Kopke RD. Reduced formation of oxidative stress biomarkers and migration of mononuclear phagocytes in the cochleae of chinchilla after antioxidant treatment in acute acoustic trauma. International J Otolaryngol 2011; in press.