A new risk factor for the development of non-alcoholic fatty liver disease: HLA complex genes

Turkish Journal of Gastroenterology

Volumn 22, Issue 4, 2011, Pages 395-399

  Çelikbilek, Mehmet ^a   Selçuk, Haldun ^a   Yilmaz, Uǧur ^a  

^a BASKENT UNIVERSITY   (Turkey)

Author keywords

Genetic; Hepatosteatosis; Human leukocyte antigen (HLA); Non alcoholic fatty liver disease

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; HLA A1 ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; HLA B27 ANTIGEN; HLA B35 ANTIGEN; HLA B44 ANTIGEN; HLA B51 ANTIGEN; HLA B57 ANTIGEN; HLA B60 ANTIGEN; HLA B7 ANTIGEN; HLA B8 ANTIGEN; HLA DQ2 ANTIGEN; HLA DQ8 ANTIGEN; HLA DQB1 ANTIGEN; HLA DR ANTIGEN; HLA DR11 ANTIGEN; HLA DR15 ANTIGEN; HLA DR7 ANTIGEN;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CYTOMEGALOVIRUS; DIABETES MELLITUS; DISEASE COURSE; ECHOGRAPHY; FEMALE; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HLA SYSTEM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HYPERLIPIDEMIA; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; OUTCOME ASSESSMENT; RISK FACTOR;

ADULT; AGED; ALANINE TRANSAMINASE; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; CYTOTOXICITY TESTS, IMMUNOLOGIC; FATTY LIVER; FEMALE; GENES, MHC CLASS I; GENES, MHC CLASS II; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; RISK FACTORS;

EID: 80052699969     PISSN: 13004948     EISSN: None     Source Type: Journal    
DOI: 10.4318/tjg.2011.0237     Document Type: Article

References (29)

1. Chitturi S, Farrell G, George J. Non-alcoholic steatohepatitis in the Asia-Pacific region: future shock? J Gastroenterol Hepatol 2004; 19: 368-74.
2. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002; 346: 1221-31.
3. Ahishali E, Demir K, Ahishali B, et al. Electron microscopic findings in nonalcoholic fatty liver disease: is there any difference between hepatosteatosis and steatohepatitis? J Hepatology 2008; 48(Suppl 2): S341.
4. Ekstedt M, Franzén LE, Mathiesen UL, et al. Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 2006; 44: 865-73. (Pubitemid 46489550)
5. Sass DA, Chang P, Chopra KB. Nonalcoholic fatty liver disease: a clinical review. Dig Dis Sci 2005; 50: 171-80. (Pubitemid 40379159)
6. Marchesini G, Bugianesi E, Forlani G, et al. Non-alcoholic fatty liver, steatohepatitis and the metabolic syndrome. Hepatology 2003; 37: 917-23. (Pubitemid 36397405)
7. Musso G, Gambino R, Bo S, et al. Should nonalcoholic fatty liver disease be included in the definition of metabolic syndrome? A cross-sectional comparison with ATP III criteria in non-obese non-diabetic subjects. Diabetes Care 2008; 31: 562-8.
8. Lizardi-Cervera J, Chavez-Tapia NC, Pérez-Bautista O, et al. Association among C-reactive protein, fatty liver disease, and cardiovascular risk. Dig Dis Sci 2007; 52: 2375-9. (Pubitemid 47246489)
9. Wilfred de Alwis NM, Day CP. Non-alcoholic fatty liver disease: the mist gradually clears. J Hepatology 2008; 48: 104-12.
10. Struben VM, Hespenheide EE, Caldwell SH. Nonalcoholic steatohepatitis and cryptogenic cirrhosis within kindreds. Am J Med 2000; 108: 9-13. (Pubitemid 30058272)
11. Willner IR, Waters B, Patil SR, et al. Ninety patients with nonalcoholic steatohepatitis: insulin resistance, familial tendency, and severity of disease. Am J Gastroenterol 2001; 96: 2957-61. (Pubitemid 32959539)
12. Angulo P, Lindor KD. Non-alcoholic fatty liver disease. J Gastroenterol Hepatol 2002; 17(Suppl): 186-90.
13. Browning JD, Kumar KS, Saboorian MH, Thiele DL. Ethnic differences in the prevalence of cryptogenic cirrhosis. Am J Gastroenterol 2004; 99: 292-8. (Pubitemid 38279872)
14. Caldwell SH, Harris DM, Patrie JT, Hespenheide EE. Is NASH underdiagnosed among African Americans? Am J Gastroenterol 2002; 97: 1496-500.
15. HLA in Health and Disease. In: Lechler R, Warrens A, eds. London: Academic Press, 2000.
16. Quinn SF, Gosink BB. Characteristic sonographic signs of hepatic fatty infiltration. Am J Roentgenol 1985; 145: 753-5. (Pubitemid 16216509)
17. Joseph AE, Saverymuttu SH, al-Sam S, et al. Comparison of liver histology with ultrasonography in assessing diffuse parenchymal liver disease. Clin Radiol 1991; 43: 26-31.
18. Needleman L, Kurtz AB, Rifkin MD, et al. Sonography of diffuse benign liver disease: accuracy of pattern recognition and grading. Am J Roentgenol 1986; 146: 1011-5. (Pubitemid 16120017)
19. Terasaki PI, Bernoco D, Park MS, et al. Microdroplet testing for HLA-A, -B, -C and -D antigens. The Phillip Levine Award Lecture. Am J Clin Pathol 1978; 69: 103-20. (Pubitemid 8299128)
20. Buyse I, Decorte R, Baens M, et al. Rapid DNA typing of class II HLA antigens using the polymerase chain reaction and reverse dot blot hybridization. Tissue Antigens 1993; 41: 1-14. (Pubitemid 23069015)
21. Singh R, Kaul R, Kaul A, Khan K. A comparative review of HLA associations with hepatitis B and C viral infections across global populations. World J Gastroenterol 2007; 13: 1770-87. (Pubitemid 46706009)
22. Diepolder HM, Jung MC, Keller E, et al. A vigorous virus-specific CD4+ T cell response may contribute to the association of HLA-DR13 with viral clearance in hepatitis B. Clin Exp Immunol 1998; 113: 244-51. (Pubitemid 28352843)
23. Hong X, Yu RB, Sun NX, et al. Human leukocyte antigen class II DQB1*0301, DRB1*1101 alleles and spontaneous clearance of hepatitis C virus infection: a meta-analysis. World J Gastroenterol 2005; 11: 7302-7. (Pubitemid 43137680)
24. Cassinotti A, Birindelli S, Clerici M, et al. HLA and autoimmune digestive disease: a clinically oriented review for gastroenterologists. Am J Gastroenterol 2009; 104(1): 195-217.
25. Yoshizawa T, Akashiba T, Kurashina K, et al. Genetic and obstructive sleep apnoea syndrome: a study of human leukocyte antigen (HLA) typing. Int Med 1993; 32: 94-7.
26. Miyamoto K, Ishii H, Takata H, et al. Association of HLA-B40 and DRW9 with Japanese alcoholic liver cirrhosis. Pharmacol Biochem Behav 1983; 18 (Suppl 1): 467-71.
27. Doffoel M, Tongio MM, Gut JP, et al. Relationships between 34 HLA-A, HLA-B and HLA-DR antigens and three serological markers of viral infections in alcoholic cirrhosis. Hepatology 1986; 6(3): 457-63.
28. Mills PR, MacSween RN, Dick HM, Hislop WS. Histocompatibility antigens in patients with alcoholic liver disease in Scotland and northeastern England: failure to show an association. Gut 1988; 29(2): 146-8. (Pubitemid 18078879)
29. Saadeh S, Younossi ZM, Remer EM, et al. The utility of radiological imaging in nonalcoholic fatty liver disease. Gastroenterology 2002; 123: 745-50. (Pubitemid 34977081)