Randomized, placebo-controlled, double-blind trial of Swedish snus for smoking reduction and cessation

Harm Reduction Journal

Volumn 8, Issue , 2011, Pages

  Joksić, Gordana ^a   Spasojević Tišma, Vera ^a   Antić, Ruza ^b   Nilsson, Robert ^b   Rutqvist, Lars E ^c  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b Academic Association for Research on Occupational and Public Health   (Serbia)

^c Swedish Match AB   (Sweden)

Author keywords

Double blind; Placebo controlled; Randomized trial; Smoking cessation; Swedish snussmoking reduction

Indexed keywords

PLACEBO;

ADULT; AGED; ARTICLE; CIGARETTE SMOKING; CLINICAL PROTOCOL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HEALTH CENTER; HUMAN; MALE; NORMAL HUMAN; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; RISK; SERBIA; SMOKELESS TOBACCO; SMOKING CESSATION;

EID: 80052690520     PISSN: None     EISSN: 14777517     Source Type: Journal    
DOI: 10.1186/1477-7517-8-25     Document Type: Article

References (29)

1. WHO Report on the Global Tobacco Epidemic, 2008: the MPOWER package. 2008, Geneva, World Health Organization.
2. Institute of Public Health of Serbia "Dr Milan Jovanović Batut". Health of Population of Serbia: analytical study 1997-2007. Belgrade 2009,
3. Mackay J, Eriksen M, Shafey O. The Tobacco Atlas. American Cancer Society 2006,
4. Foulds J, Ramström L, Burke M, Fagerström K. The effects of smokeless tobacco (snus) on smoking and public health in Sweden. Tobacco Control 2003, 12:349-359. 10.1136/tc.12.4.349, 1747791, 14660766.
5. Royal College of Physicians. 2002, Protecting Smokers, Saving Lives, Publications Unit of the Royal College of Physicians, London.
6. Lee PN, Hamling J. Systematic review of the relation between smokeless tobacco and cancer in Europe and North America. BMC Med 2009, 29:36.
7. Lee PN. Summary of the epidemiological evidence relating snus to health. Regul Toxicol Pharmacol 2011, 59:197-214. 10.1016/j.yrtph.2010.12.002, 21163315.
8. Moore D, Aveyard P, Connock M, Wang D, Fry-Smith A, Barton P. Effectiveness and safety of nicotine replacement therapy assisted reduction to stop smoking: systematic review and meta-analysis. BMJ 2009, 338:b1024. 10.1136/bmj.b1024, 2664870, 19342408.
9. Rodu B, Cole P. Lung cancer mortality: comparing Sweden with other countries in the European Union. Scand J Public Health 2010, 38:332-3. 10.1177/1403494810364203, 20435619.
10. Swedish National Board of Health and Welfare. Public Health Report 2005 (In Swedish). Socialstyrelsen, Stockholm 2006,
11. Lund K, Scheffels J, McNeill A. The association between use of snus and quit rates for smoking: results from seven Norwegian cross-sectional studies. Addiction 2011, 106:162-167. 10.1111/j.1360-0443.2010.03122.x, 3021722, 20883459.
12. Ramström L, et al. Commentary on Lund Consolidating the evidence on effectiveness of snus for smoking cessation - implications for public health. Addiction 2011, 106:168-169. 10.1111/j.1360-0443.2010.03180.x, 21618730, Commentary on Lund.
13. World Health Organization WHO Study Group on Tobacco Product Regulation. Report on the scientific basis of tobacco product regulation: third report of a WHO study group. 2009, WHO Technical Report Series 955, Geneva, Switzerland, World Health Organization.
14. Asfar T, Ebbert JO, Klesges RC, Relyea GE. Do smoking reduction interventions promote cessation in smokers not ready to quit?. Addict Behav 2011, 36:764-768. 10.1016/j.addbeh.2011.02.003, 21420791.
15. International conference on harmonisation of technical requirements for registration of pharmaceuticals for human use. ICH-GCP Good Clinical Practice Retrieved July 2011., http://ichgcp.net
16. Rutqvist LE, Curvall M, Hassler T, Ringberger T, Wahlberg I. Swedish snus and the GothiaTek® standard. Harm Reduction Journal 2011, 8:11. 10.1186/1477-7517-8-11, 3119032, 21575206.
17. Lunell E, Lunell M. Steady-state nicotine plasma levels following use of four different types of Swedish snus compared with 2-mg Nicorette chewing gum: a crossover study. Nicotine Tob Res 2005, 7:397-403. 10.1080/14622200500125468, 16085507.
18. Benowitz NL, Porchet H, Sheiner L, Jacob P. Nicotine absorption and cardiovascular effects with smokeless tobacco use: comparison with cigarettes and nicotine gum. Clin Pharmacol Ther 1988, 44:23-28. 10.1038/clpt.1988.107, 3391001.
19. Heatherton TF, Kozlowski LT, Frecker RC, Fagerström KO. The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire. Br J Addict 1991, 86:1119-1127. 10.1111/j.1360-0443.1991.tb01879.x, 1932883.
20. European Medicines Agency (EMA) Statistical principles for clinical trials. September 1998. Retrieved July 2011, European Medicines Agency (EMA)., http://www.ema.europa.eu/pdfs/human/ich/036396en.pdf
21. Simmons MS, Connett JE, Nides MA, Lindgren PG, Kleerup EC, Murray RP, Bjornson WM, Tashkin DP. Smoking reduction and the rate of decline in FEV1: results from the Lung Health Study. Eur Respir J 2005, 25:1011-7. 10.1183/09031936.05.00086804, 15929955.
22. Tönnesen P, Mikkelsen K, Bremann L. Nurse-conducted smoking cessation in patients with COPD using nicotine sublingual tablets and behavioral support. Nicotine Tob Res 2005, 7:139-48. 10.1080/14622200412331328411, 15804686.
23. Gilljam H, Galanti MR. Role of snus (oral moist snuff) in smoking cessation and smoking reduction in Sweden. Addiction 2003, 98:1183-9. 10.1046/j.1360-0443.2003.00379.x, 12930201.
24. Hajek P, Jackson P, Belcher M. Long-term Use of Nicotine Chewing Gum: Occurrence, Determinants, and Effect on Weight Gain. JAMA 1988, 260:1593-1596. 10.1001/jama.260.11.1593, 3411739.
25. Jarvis MJ, Raw M, Russell MAH, Feyerabend C. Randomised controlled trial of nicotine chewing-gum. BMJ 1982, 285:537-540. 10.1136/bmj.285.6341.537, 1499070, 6809161.
26. Murray RP, Bailey WC, Daniels K, Bjornson WM, Kurnow K, Connett JE, Nides MA, Kiley JP. Safety of Nicotine Polacrilex Gum Used by 3,094 Participants in the Lung Health Study. Chest 1996, 109:438-445. 10.1378/chest.109.2.438, 8620719.
27. Lund K-E, McNeill A, Scheffels J. The use of snus for quitting smoking compared with medicinal products. Nicotine Tob Res 2010, 12:817-822. 10.1093/ntr/ntq105, 2910876, 20622023.
28. Ramström LM, Foulds J. Role of snus in initiation and cessation of tobacco smoking in Sweden. Tobacco Control 2006, 15:210-214. 10.1136/tc.2005.014969, 2564662, 16728752.
29. Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) Health Effects of Smokeless Tobacco Products 2008, European Commission, Brussels, Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR).