Expression study on the porcine PTHLH gene and its relationship with sow teat number

Journal of Animal Breeding and Genetics

Volumn 128, Issue 5, 2011, Pages 344-353

  Martinez Giner M ^a   Noguera, J L ^a   Balcells, I ^b   Alves, E ^c   Varona, L ^a,d   Pena, R N ^a  

^a IRTA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c INIA   (Spain)

^d UNIVERSIDAD DE ZARAGOZA   (Spain)

Author keywords

Parathyroid hormone like hormone; Pig; QPCR; QTL; Teat number

Indexed keywords

PARATHYROID HORMONE RELATED PROTEIN;

ALTERNATIVE RNA SPLICING; ANIMAL; ARTICLE; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HISTOLOGY; MALE; PHENOTYPE; SWINE; UDDER;

ALTERNATIVE SPLICING; ANIMALS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOTYPE; MALE; MAMMARY GLANDS, ANIMAL; PARATHYROID HORMONE-RELATED PROTEIN; PHENOTYPE; POLYMORPHISM, GENETIC; SUS SCROFA;

SUIDAE; SUS;

EID: 80052679384     PISSN: 09312668     EISSN: 14390388     Source Type: Journal    
DOI: 10.1111/j.1439-0388.2011.00925.x     Document Type: Article

References (30)

1. Chomdej S., Ponsuksili S., Schellander K., Wimmers K. (2004) Sequencing, SNP identification and mapping of the porcine PTHLH gene to chromosome 5. Anim. Genet., 35, 151-152.
2. Dèspres P., Martinat-Botte F., Lagant H., Terqui M., Legault C. (1992) A comparison of reproductive performance in Large White, hyperprolific Large White and Meishan sows. Journées de la Recherche Porcine en France, 24, 345-350.
3. Dunbar M.E., Young P., Zhang J.P., McCaughern-Carucci J., Lanske B., Orloff J.J., Karaplis A., Cunha G., Wysolmerski J.J. (1998) Stromal cells are critical targets in the regulation of mammary ductal morphogenesis by parathyroid hormone-related protein. Dev. Biol., 203, 75-89.
4. Gelfand A.E., Smith A.F.M. (1990) Sampling-based approaches to calculating marginal densities. J. Am. Stat. Assoc., 85, 398-409.
5. Huang X., Madan A. (1999) CAP3: a DNA sequence assembly program. Genome Res., 9, 868-877.
6. Kobayashi T., Kronenberg H.M., Foley J. (2005) Reduced expression of the PTH/PTHrP receptor during development of the mammary gland influences the function of the nipple during lactation. Dev. Dyn., 233, 794-803.
7. Larkin M.A., Blackshields G., Brown N.P., Chenna R., McGettigan P.A., McWilliam H., Valentin F., Wallace I.M., Wilm A., Lopez R., Thompson J.D., Gibson T.J., Higgins D.G. (2007) ClustalW and ClustalX version 2. Bioinformatics, 23, 2947-2948.
8. T method. Methods, 25, 402-408.
9. Mangin M., Ikeda K., Dreyer B.E., Broadus A.E. (1989) Isolation and characterization of the human parathyroid hormone-like peptide gene. Proc. Natl Acad. Sci. U.S.A., 86, 2408-2412.
10. Noguera J.L., Varona L., Babot D., Estany J. (2002) Multivariate analysis of litter size for multiple parities with production traits in pigs: II. Response to selection for litter size and correlated response to production traits. J. Anim. Sci., 80, 2548-2555.
11. O'Dowd R., Kent J.C., Moseley J.M., Wlodek M.E. (2008) Effects of uteroplacental insufficiency and reducing litter size on maternal mammary function and postnatal offspring growth. Am. J. Physiol. Regul. Integr. Comp. Physiol., 294, 539-548.
12. Onda K., Sato A., Yamaguchi M., Matsuki N., Ono K., Wada Y. (2006) Parathyroid hormone-related protein (PTHrP) and Ca levels in the milk of lactating cows. J. Vet. Med. Sci., 68, 709-713.
13. Philbrick W.M., Wysolmersky J.J., Galbraith S., Holt E., Orloff J.J., Yang K.H., Vasavada R.C., Weir E.C., Broadus A.E., Stewart A.F. (1996) Defining the roles of parathyroid hormone-related protein in normal physiology. Physiol. Rev., 76, 127-173.
14. Raftery A.E., Lewis S.M. (1992) How many iterations in the Gibbs sampler? In: J.M. Bernardo, J.O. Berger, A.P. Dawid, A.F.M. Smith (eds)Bayesian Statistics 4. Oxford University Press, Oxford, pp. 763-773.
15. Robinson G.W., Karpf A.B., Kratochwil K. (1999) Regulation of mammary gland development by tissue interaction. J. Mammary Gland Biol. Neoplasia, 4, 9-19.
16. Rodríguez C., Tomás A., Alves E., Ramirez O., Arqué M., Muñoz G., Barragán C., Varona L., Silió L., Amills M., Noguera J.L. (2005) QTL mapping for teat number in an Iberian-by-Meishan pig intercross. Anim. Genet., 36, 490-496.
17. Rosol T.J., Steinmeyer C.L., McCauley L.K., Gröne A., Dewille J.W., Capen C.C. (1995) Sequences of the cDNAs encoding canine parathyroid hormone-related protein and parathyroid hormone. Gene, 160, 241-243.
18. Sellers R.S., Luchin A.I., Richard V., Brena R.M., Lima D., Rosol T.J. (2004) Alternative splicing of parathyroid hormone-related protein mRNA: expression and stability. J. Mol. Endocrinol., 33, 227-241.
19. Sorensen D.A., Andersen S., Gianola D., Korsgaard I. (1995) Bayesian-inference in threshold models using Gibbs sampling. Genet. Sel. Evol., 27, 229-249.
20. Sorensen D.A., Vernersen A., Andersen S. (2000) Bayesian analysis of response to selection: a case study using litter size in Danish Yorkshire pigs. Genetics, 156, 283-295.
21. Spiegelhalter D.J., Best N.G., Carlin B.P., van der Linde A. (2002) Bayesian measures of model complexity and fit. J. R. Stat. Soc. B, 64, 583-639.
22. Suva L.J., Mather K.A., Gillespie M.T., Webb G.C., Ng K.W., Winslow G.A., Wood W.I., Martin T.J., Hudson P.J. (1989) Structure of the 5' flanking region of the gene encoding human Parathyroid-Hormone-Related protein (PTHRP). Gene, 77, 95-105.
23. Toro M.A., Dobao M.T., Rodriganez J., Silio L. (1986) Heritability of a canalized trait - Teat number in Iberian pigs. Genet. Sel. Evol., 18, 173-183.
24. Van Genderen C., Okamura R.M., Fariñas I., Quo R.G., Parslow T.G., Bruhn L., Grosschedl R. (1994) Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev., 8, 2691-2703.
25. Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., Speleman F. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol., 3, 34.1-34.11.
26. Varona L., Gómez-Raya L., Rauw W.M., Ovilo C., Clop A., Noguera J.L. (2005) The value of prior information for detection of QTL affecting longitudinal traïts: an example using Von Bertalanffy growth function. J. Anim. Breed. Genet., 122, 37-48.
27. Wysolmerski J.J., Philbrick W.M., Dunbar M.E., Lanske B., Kronenberg H., Broadus A.E. (1998) Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development. Development, 125, 1285-1294.
28. Yasuda T., Banville D., Hendy G.N., Goltzman D. (1989a) Characterization of the human parathyroid hormone-like peptide gene - functional and evolutionary aspects. J. Biol. Chem., 264, 7720-7725.
29. Yasuda T., Banville D., Rabbani S.A., Hendy G.N., Goltzman D. (1989b) Rat Parathyroid Hormone-Like Peptide - Comparison with the human homolog and expression in malignant and normal tissue. Mol. Endocrinol., 3, 518-525.
30. Zhao L., Roche P.J., Gunnersen J.M., Hammond V.E., Tregear G.W., Marelyn E., Wintour E.M., Beck F. (1999) Mice without a functional relaxin gene are unable to deliver milk to their pups. Endocrinology, 140, 445-453.