Lung transplantation affects expression of the chemokine receptor type 4 on specific T cell subsets

Clinical and Experimental Immunology

Volumn 166, Issue 1, 2011, Pages 103-109

  Paantjens, A W M ^a   van de Graaf, E A ^a   Kwakkel van Erp, J M ^a   Hoefnagel, T ^a   van Kessel, D A ^b   van den Bosch, J M M ^b   Otten, H G ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ST ANTONIUS HOSPITAL   (Netherlands)

Author keywords

BOS; CCR4; Lung transplantation; T cell subsets; TARC

Indexed keywords

CHEMOKINE RECEPTOR CCR4; THYMUS AND ACTIVATION REGULATED CHEMOKINE;

ADULT; ARTICLE; BRONCHIOLITIS OBLITERANS; CD4+ T LYMPHOCYTE; CHRONIC GRAFT REJECTION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; LUNG TRANSPLANTATION; MALE; MEMORY T LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE;

ADULT; BIOLOGICAL MARKERS; BRONCHIOLITIS OBLITERANS; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CCL17; CHEMOKINE CCL2; CHEMOKINE CCL22; FEMALE; FLOW CYTOMETRY; GRAFT REJECTION; HUMANS; LUNG TRANSPLANTATION; MALE; MIDDLE AGED; RECEPTORS, CCR4; SYNDROME; T-LYMPHOCYTE SUBSETS; TIME FACTORS;

EID: 80052646454     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2011.04450.x     Document Type: Article

References (21)

1. Burke CM, Theodore J, Dawkins KD etal. Post-transplant obliterative bronchiolitis and other late lung sequelae in human heart-lung transplantation. Chest 1984; 86:824-9.
2. Estenne M, Maurer JR, Boehler A etal. Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria. J Heart Lung Transplant 2002; 21:297-310.
3. Paantjens AW, Kwakkel-van Erp JM, van Ginkel WG etal. Serum thymus and activation regulated chemokine levels post-lung transplantation as a predictor for the bronchiolitis obliterans syndrome. Clin Exp Immunol 2008; 154:202-8.
4. Belperio JA, Keane MP, Burdick MD etal. Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome. J Clin Invest 2001; 108:547-6.
5. Meloni F, Solari N, Miserere S etal. Chemokine redundancy in BOS pathogenesis. A possible role also for the CC chemokines: MIP3-beta, MIP3-alpha, MDC and their specific receptors. Transpl Immunol 2008; 18:275-80.
6. Bhorade SM, Chen H, Molinero L etal. Decreased percentage of CD4+FoxP3+ cells in bronchoalveolar lavage from lung transplant recipients correlates with development of bronchiolitis obliterans syndrome. Transplantation 2010; 90:540-6.
7. Kunkel EJ, Boisvert J, Murphy K etal. Expression of the chemokine receptors CCR4, CCR5, and CXCR3 by human tissue-infiltrating lymphocytes. Am J Pathol 2002; 160:347-55.
8. Gregson AL, Hoji A, Palchevskiy V etal. Protection against bronchiolitis obliterans syndrome is associated with allograft CCR7+ CD45RA- T regulatory cells. PLoS ONE 2010; 5:e11354.
9. Vijayanand P, Durkin K, Hartmann G etal. Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients. J Immunol 2010; 184:4568-74.
10. Stolberg VR, Chiu BC, Schmidt BM, Kunkel SL, Sandor M, Chensue SW. CC Chemokine receptor 4 contributes to innate NK and chronic stage T helper cell recall responses during Mycobacterium bovis. Infection 2011; 178:233-44.
11. Yogo Y, Fujishima S, Inoue T etal. Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis. Respir Res 2009; 10:80.
12. Hijnen D, De Bruin-Weller M, Oosting B etal. Serum thymus and activation-regulated chemokine (TARC) and cutaneous T cell-attracting chemokine (CTACK) levels in allergic diseases: TARC and CTACK are disease-specific markers for atopic dermatitis. J Allergy Clin Immunol 2004; 113:334-40.
13. Paantjens AW, van de Graaf EA, van Ginkel WG, van den Bosch JM, Otten HG. Lung transplantation under a tacrolimus/mycophenolate mofetil-based immunosuppressive regimen results in low titers of HLA and MICA IgG antibodies which are not related to development of BOS. J Heart Lung Transplant 2010; 29:596.
14. Morimoto Y, Bian Y, Gao P etal. Induction of surface CCR4 and its functionality in mouse Th2 cells is regulated differently during Th2 development. J Leukoc Biol 2005; 78:753-61.
15. Iellem A, Mariani M, Lang R etal. Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells. J Exp Med 2001; 194:847-53.
16. Bauwens AM, van de Graaf EA, van Ginkel WG, van Kessel DA, Otten HG. Pre-transplant soluble CD30 is associated with bronchiolitis obliterans syndrome after lung transplantation. J Heart Lung Transplant 2006; 25:416-19.
17. Kwakkel-van Erp JM, Otten HG, Paantjens AW etal. Soluble CD30 measured after lung transplantation does not predict bronchiolitis obliterans syndrome in a tacrolimus/mycophenolate mofetil-based immunosuppressive regimen. J Heart Lung Transplant 2008; 27:1172-5.
18. Fields RC, Bharat A, Steward N etal. Elevated soluble CD30 correlates with development of bronchiolitis obliterans syndrome following lung transplantation. Transplantation 2006; 82:1596-601.
19. Golocheikine AS, Saini D, Ramachandran S, Trulock EP, Patterson A, Mohanakumar T. Soluble CD30 levels as a diagnostic marker for bronchiolitis obliterans syndrome following human lung transplantation. Transpl Immunol 2008; 18:260-3.
20. Kwakkel-van Erp JM, Haeck IM, Paantjens AW etal. Differential usefulness of biomarkers thymus and activation-regulated chemokine and soluble CD30 during enteric coated mycophenolate sodium and cyclosporine therapy in atopic dermatitis. J Am Acad Dermatol 2010; 63:e70-2.
21. Berin MC, Eckmann L, Broide DH, Kagnoff MF. Regulated production of the T helper 2-type T-cell chemoattractant TARC by human bronchial epithelial cells in vitro and in human lung xenografts. Am J Respir Cell Mol Biol 2001; 24:382-9.