Safety of intravenous thrombolysis within 4.5 h of symptom onset in patients with negative post-treatment stroke imaging for cerebral infarction

Neurocritical Care

Volumn 15, Issue 1, 2011, Pages 76-79

  Giraldo, Elias A ^a   Khalid, Aisha ^b   Zand, Ramin ^b  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Acute ischemic stroke; Stroke imaging; Stroke mimics; Thrombolysis; TIA

Indexed keywords

ALTEPLASE;

ADULT; ARTICLE; BLOOD CLOT LYSIS; BRAIN HEMORRHAGE; BRAIN INFARCTION; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; DRUG SAFETY; FEMALE; GINGIVA BLEEDING; HOSPITALIZATION; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MIGRAINE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; ONSET AGE; OUTCOME ASSESSMENT; PARALYSIS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SOMATOFORM DISORDER; STROKE; SYMPTOMATOLOGY; TRANSIENT ISCHEMIC ATTACK;

AGED; CEREBRAL INFARCTION; DIFFUSION MAGNETIC RESONANCE IMAGING; DRUG ADMINISTRATION SCHEDULE; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; ISCHEMIC ATTACK, TRANSIENT; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; STROKE; THROMBOLYTIC THERAPY; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME;

EID: 80052634761     PISSN: 15416933     EISSN: 15560961     Source Type: Journal    
DOI: 10.1007/s12028-011-9523-x     Document Type: Article

References (13)

1. Lees KR, Bluhmki E, von Kummer R, et al. Time to treatment with intravenous alteplase and outcome in stroke: An updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010;375:1695-703.
2. Schellinger PD, Bryan RN, Caplan LR, et al. Evidence-based guideline: The role of diffusion and perfusion MRI for the diagnosis of acute ischemic stroke: Report of the therapeutics and technology assessment subcommittee of the American Academy of Neurology. Neurology. 2010;75:177-85.
3. Oppenheim C, Stanescu R, Dormont D, et al. False-negative diffusion-weighted MR findings in acute ischemic stroke. Am J Neuroradiol. 2000;21:1434-40.
4. Huff JS. Stroke mimics and chameleons. Emerg Med Clin North Am. 2002;20:583-95.
5. Yew KS, Cheng E. Acute stroke diagnosis. Am Fam Physician. 2009;80:33-40.
6. Chernyshev OY, Martin-Schild S, Albright KC, et al. Safety of tPA in stroke mimics and neuroimaging-negative cerebral ischemia. Neurology. 2010;74:1340-5.
7. Winkler DT, Fluri F, Fuhr P, et al. Thrombolysis in stroke mimics: Frequency, clinical characteristics, and outcome. Stroke. 2009;40:1522-5.
8. Uchino K, Massaro L, Hammer MD. Transient ischemic attack after tissue plasminogen activator: Aborted stroke or unnecessary stroke therapy? Cerebrovasc Dis. 2010;29:57-61.
9. Caplan L, Mohr J, Kistler J, Koroshetz W. Should thrombolytic therapy be the first-line treatment for acute ischemic stroke? Thrombolysis-not a panacea for ischemic stroke. N Engl J Med. 1997;337:1309-10. (Pubitemid 27461290)
10. Scott PA, Silbergleit R. Misdiagnosis of stroke in tissue plasminogen activator-treated patients: Characteristics and outcomes. Ann Emerg Med. 2003;42:611-8. (Pubitemid 37329015)
11. Vroomen P, Buddingh M, Luijckx G, et al. The incidence of stroke mimics among stroke department admissions in relation to age group. J Stroke Cerebrovasc Dis. 2008;17:418-22.
12. Hand P, Kwan J, Lindley R, Dennis M, Wardlaw J. Distinguishing between stroke and mimic at the bedside: The brain attack study. Stroke. 2006;37:769-75. (Pubitemid 43731907)
13. Hemmen TM, Meyer BC, McClean TL, Lyden PD. Identification of nonischemic stroke mimics among 411 code strokes at the University of California, San Diego, Stroke Center. J Stroke Cerebrovasc Dis. 2008;17:23-5.