[11C]acetate PET/CT visualizes skeletal muscle exercise participation, impaired function, and recovery after hip arthroplasty; first results

Molecular Imaging and Biology

Volumn 13, Issue 4, 2011, Pages 793-799

  Buchegger, Franz ^a   Ratib, Osman ^a   Willi, Jean Pierre ^a   Steiner, Charles ^a   Seimbille, Yann ^a   Zaidi, Habib ^a   Graf, V́ronique ^a   Peter, Robin ^a   Jung, Maximilien ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

11C acetate; Hip arthroplasty; Muscle injury; PET CT; Skeletal muscle exercise PET

Indexed keywords

ACETIC ACID C 11; ACETIC ACID DERIVATIVE; CARBON; DIAGNOSTIC AGENT;

ADULT; ARTICLE; CASE REPORT; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; DRUG UPTAKE; EXERCISE; FUNCTIONAL STATUS; GLUTEUS MAXIMUS MUSCLE; HIP ARTHROPLASTY; HUMAN; HUMAN TISSUE; ILIACUS MUSCLE; IMAGE ANALYSIS; INTERNAL OBTURATOR MUSCLE; MALE; MUSCLE FUNCTION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PSOAS MUSCLE; SCINTISCANNING; SKELETAL MUSCLE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONVALESCENCE; HIP; KINESIOTHERAPY; METHODOLOGY; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; RADIOGRAPHY; REST;

ACETATES; ARTHROPLASTY, REPLACEMENT, HIP; CARBON RADIOISOTOPES; EXERCISE THERAPY; HIP; HUMANS; MALE; MIDDLE AGED; MUSCLE, SKELETAL; POSITRON-EMISSION TOMOGRAPHY; RECOVERY OF FUNCTION; REST; TOMOGRAPHY, X-RAY COMPUTED;

EID: 80052632262     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-010-0415-9     Document Type: Article

References (26)

1. Skutches CL, Holroyde CP, Myers RN, Paul P, Reichard GA (1979) Plasma acetate turnover and oxidation. J Clin Invest 64:708-713 (Pubitemid 10223746)
2. Pouteau E, Piloquet H, Maugeais P, Champ M, Dumon H, Nguyen P, Krempf M (1996) Kinetic aspects of acetate metabolism in healthy humans using [1-13C] acetate. Am J Physiol 271:E58-E64
3. Mittendorfer B, Sidossis LS, Walser E, Chinkes DL, Wolfe RR (1998) Regional acetate kinetics and oxidation in human volunteers. Am J Physiol 274:E978-E983 (Pubitemid 28308781)
4. van Hall G, Sacchetti M, Radegran G (2002) Whole body and leg acetate kinetics at rest, during exercise and recovery in humans. J Physiol 542:263-272 (Pubitemid 35190288)
5. 99mTc-MIBI SPET. Eur J Nucl Med Mol Imaging 31:13-21 (Pubitemid 38133536)
6. 11C]acetate synthesis in GMP conditions. Appl Radiat Isot 64:995-1000 (Pubitemid 44137478)
7. Michel C, Sibomana M, Boi A, Bernard X, Lonneux M, Defrise M, Comtat C, Kinahan PE, Townsend DW (1998) Preserving Poisson characteristics of PET data with weighted OSEM reconstruction. IEEE Nuclear Science Symp Medical Imaging Conf 2:1323-1329
8. Kemppainen J, Fujimoto T, Kalliokoski KK, Viljanen T, Nuutila P, Knuuti J (2002) Myocardial and skeletal muscle glucose uptake during exercise in humans. J Physiol 542:403-412 (Pubitemid 35190303)
9. 18F]fluoro-2-deoxy-D-glucose. Int J Radiat Oncol Biol Phys 59:1295-1300 (Pubitemid 38954050)
10. Pappas GP, Olcott EW, Drace JE (2001) Imaging of skeletal muscle function using (18)FDG PET: Force production, activation, and metabolism. J Appl Physiol 90:329-337 (Pubitemid 32038535)
11. Schelbert HR (1987) Positron emission tomography. Diagnostic and therapeutic implications in human myocardial ischemia. Int J Card Imaging 2:199-208 (Pubitemid 18040995)
12. Beanlands RS, Bach DS, Raylman R, Armstrong WF, Wilson V, Montieth M, Moore CK, Bates E, Schwaiger M (1993) Acute effects of dobutamine on myocardial oxygen consumption and cardiac efficiency measured using carbon-11 acetate kinetics in patients with dilated cardiomyopathy. J Am Coll Cardiol 22:1389-1398 (Pubitemid 23316364)
13. Bengel FM, Ueberfuhr P, Nekolla S, Ziegler SI, Reichart B, Schwaiger M (1999) Oxidative metabolism of the transplanted human heart assessed by positron emission tomography using C-11 acetate. Am J Cardiol 83:1503-1505, A8
14. 11C]acetate as a tracer of cardiac oxidative metabolism. Am J Physiol 266:H1304-H1315
15. 11C]acetate and dynamic positron tomography. Circulation 80:863-872 (Pubitemid 19261634)
16. 11C] acetate as a tracer for noninvasive assessment of oxidative metabolism with positron emission tomography in normal, ischemic, postischemic, and hyperemic canine myocardium. Circulation 81:1594-1605 (Pubitemid 20158299)
17. Buck A, Wolpers HG, Hutchins GD, Savas V, Mangner TJ, Nguyen N, Schwaiger M (1991) Effect of carbon-11-acetate recirculation on estimates of myocardial oxygen consumption by PET. J Nucl Med 32:1950-1957
18. Wolpers HG, Buck A, Nguyen N, Marcowitz PA, Armstrong WF, Starling MR, Hicks R, Mangner TJ, Schwaiger M (1994) An approach to ventricular efficiency by use of carbon 11-labeled acetate and positron emission tomography. J Nucl Cardiol 1:262-269 (Pubitemid 24317232)
19. Sidossis LS, Coggan AR, Gastaldelli A, Wolfe RR (1995) Pathway of free fatty acid oxidation in human subjects. Implications for tracer studies. J Clin Invest 95:278-284
20. Kudo T, Hata T, Kagawa S, Kishibe Y, Iwasaki J, Nakano A, Okazawa H (2008) Simple quantification of myocardial perfusion by pixel-bypixel graphical analysis using carbon-11 acetate: Comparison of the Kcomplexes of carbon-11 acetate and nitrogen-13 ammonia. Nucl Med Commun 29:679-685
21. 18F-fluorodeoxyglucose positron emission tomography. J Orthop Sci 11:42-45 (Pubitemid 43155855)
22. Laaksonen MS, Kalliokoski KK, Kyrolainen H, Kemppainen J, Teras M, Sipila H, Nuutila P, Knuuti J (2003) Skeletal muscle blood flow and flow heterogeneity during dynamic and isometric exercise in humans. Am J Physiol Heart Circ Physiol 284:H979-H986 (Pubitemid 36228247)
23. Kalliokoski KK, Kuusela TA, Nuutila P, Tolvanen T, Oikonen V, Teras M, Takala TE, Knuuti J (2001) Perfusion heterogeneity in human skeletal muscle: Fractal analysis of PET data. Eur J Nucl Med 28:450-456 (Pubitemid 32260910)
24. Berry DJ (2005) "Minimally invasive" total hip arthroplasty. J Bone Joint Surg Am 87:699-700 (Pubitemid 40489342)
25. Muller M, Tohtz S, Springer I, Dewey M, Perka C (2010) Randomized controlled trial of abductor muscle damage in relation to the surgical approach for primary total hip replacement: Minimally invasive anterolateral versus modified direct lateral approach. Arch Orthop Trauma Surg. doi:10.1007/s00402- 010-1117-0
26. Pfirrmann CW, Notzli HP, Dora C, Hodler J, Zanetti M (2005) Abductor tendons and muscles assessed at MR imaging after total hip arthroplasty in asymptomatic and symptomatic patients. Radiology 235:969-976 (Pubitemid 40695896)