Co-expression of interleukin 12 enhances antitumor effects of a novel chimeric promoter-mediated suicide gene therapy in an immunocompetent mouse model

Biochemical and Biophysical Research Communications

Volumn 412, Issue 4, 2011, Pages 763-768

  Xu, Yu ^a,b   Liu, Zhengchun ^b   Kong, Haiyan ^b   Sun, Wenjie ^a,b   Liao, Zhengkai ^a,b   Zhou, Fuxiang ^a,b   Xie, Conghua ^a,b   Zhou, Yunfeng ^a,b  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b Hubei Cancer Clinical Study Center   (China)

Author keywords

Irradiation; CArG element; Gene therapy; HRP IAA system; HTERT promoter; Interleukin 12

Indexed keywords

ADENOVIRUS VECTOR; HORSERADISH PEROXIDASE; INDOLEACETIC ACID; INTERLEUKIN 12; TELOMERASE REVERSE TRANSCRIPTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOMEGALOVIRUS; DRUG SAFETY; FEMALE; GENE TARGETING; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; LEWIS CARCINOMA; LUNG CARCINOMA; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SUICIDE GENE THERAPY; T LYMPHOCYTE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; GENE THERAPY; GENES, TRANSGENIC, SUICIDE; HUMANS; IMMUNOCOMPETENCE; INTERLEUKIN-12; LEUKEMIC INFILTRATION; LUCIFERASES; MICE; MICE, INBRED C57BL; NEOPLASMS; RESPONSE ELEMENTS; T-LYMPHOCYTES; TELOMERASE;

ADENOVIRIDAE; ARMORACIA RUSTICANA; CYTOMEGALOVIRUS; MUS;

EID: 80052621946     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.08.077     Document Type: Article

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