A comparison of the effects of ketamine, chloral hydrate and pentobarbital sodium anesthesia on isolated rat hearts and cardiomyocytes

Journal of Cardiovascular Medicine

Volumn 12, Issue 10, 2011, Pages 732-735

  Jiang, Xinwei ^a   Gao, Liping ^a   Zhang, Yang ^b   Wang, Guangming ^a   Liu, Ying ^a   Yan, Changdong ^a   Sun, Hong ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

^b Department of Anesthesiology ^*  (China)

Author keywords

cardiomyocytes; chloral hydrate; isolated heart; ketamine,pentobarbital sodium

Indexed keywords

CHLORAL HYDRATE; KETAMINE; PENTOBARBITAL;

ANESTHESIA; ANIMAL CELL; ARTICLE; CELL SHAPE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; HEART HEMODYNAMICS; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART RATE; MALE; NONHUMAN; RAT; SURVIVAL RATE;

ANESTHETICS; ANIMALS; CELL SURVIVAL; CHLORAL HYDRATE; HEART; HEART RATE; KETAMINE; MALE; MYOCYTES, CARDIAC; PENTOBARBITAL; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 80052617728     PISSN: 15582027     EISSN: 15582035     Source Type: Journal    
DOI: 10.2459/JCM.0b013e32834a6697     Document Type: Article

References (21)

1. Sutherland FJ, Hearse DJ. The isolated blood and perfusion fluid perfused heart. Pharmacol Res 2000; 41:613-627.
2. Graf BM, Martin E, Bosnjak ZJ, Stowe DF. Stereospecific effect of bupivacaine isomers on atrioventricular conduction in the isolated perfused guinea pig heart. Anesthesiology 1997; 86:410-419. (Pubitemid 27093385)
3. Moldovan M, Spulber S, Saravan V, et al. The relationship between respiratory sinus arrhythmia and heart rate during anesthesia in rat. Rom J Physiol 2004; 41:31-39.
4. Rodrigues SF, de Oliveira MA, Martins JO. Differential effects of chloral hydrate-and ketamine/xylazine-induced anesthesia by the s.c.route. Life Sci 2006; 79:1630-1637. (Pubitemid 44344729)
5. Davies AO, McCans JL. Effects of barbiturate anesthetics and ketamine on the force-frequency relation of cardiac muscle. Eur J Pharmacol 1979; 59:65-73. (Pubitemid 10242437)
6. Frankl WS, Poole-Wilson PA. Effects of thiopental on tension development, action potential, and exchange of calcium and potassium in rabbit ventricular myocardium. J Cardiovasc Pharmacol 1981; 3:554-565. (Pubitemid 11097068)
7. Saha DC, Saha AC, Malik G, et al. Comparison of cardiovascular effects of tiletamine-zolazepam, pentobarbital, and ketamine-xylazine in male rats. J Am Assoc Lab Anim Sci 2007; 46:74-80. (Pubitemid 47065768)
8. Janssen BJ, De Celle T, Debets JJ, et al. Effects of anesthetic on systemic hemodynamics in mice. Am J Physiol Heart Circ Physiol 2004; 287:H1618-1624. (Pubitemid 39313266)
9. Kim SH, Bae YM, Sung DJ, et al. Ketamine blocks voltage-gated K\+ channels and causes membrane depolarization in rat mesenteric artery myocytes. Pflü gers Arch 2007; 454:891-902. (Pubitemid 47338450)
10. Field KJ, White WJ, Lang CM. Anaesthetic effects of chloral hydrate, pentobarbitone and urethane in adult male rats. Lab Anim 1993; 27:258-269. (Pubitemid 23222285)
11. Wu Q, Zhao Z, Sun H, et al. Oestrogen changed cardiomyocyte contraction and beta-adrenoceptor expression in rat hearts subjected to ischaemia- reperfusion. Exp Physiol 2008; 93:1034-1043.
12. Yi-Ming W, Shu H, Miao CY, et al. Asynchronism of the recovery of baroreflex sensitivity, blood pressure, and consciousness from anesthesia in rats. J Cardiovasc Pharmacol 2004; 43:1-7. (Pubitemid 38032056)
13. Pacher P, Nagayama T, Mukhopadhyay P, et al. Measurement of cardiac function using pressure-volume conductance catheter technique in mice and rats. Nat Protoc 2008; 3:1422-1434.
14. Unruh HW, Wang R, Bose D, Mink SN. Does pentobarbital anesthesia depress left ventricular contractility in dogs? Am J Physiol Heart Circ Physiol 1991; 261:H700-H706.
15. Snyder DS, Harasawa Y, Sagawa K, Hunter WC. Effects of pentobarbital on inotropic state of isolated canine left ventricle. Heart Vessels 1993; 8:128-135. (Pubitemid 23244686)
16. Stowe DF, Bosnjak ZJ, Kampine JP. Comparison of etomidate, ketamine, midazolam, propofol, and thiopental on function and metabolism of isolated hearts. Anesth Analg 1992; 74:547-558.
17. Idvall J, Ahlgren I, Aronsen KR, Stenbeg P. Ketamine infusions: pharmacokinetics and clinical effects. Br J Anaesth 1979; 51:1167-1173. (Pubitemid 10171522)
18. Doenicke A, Angster R, Mayer M, et al. The action of s-(\+)-ketamine on serum catecholamine and cortisol. A comparison with ketamine racemate. Anaesthesist 1992; 41:597-603.
19. Zorniak M, Mitrega K, Bialka S, Proc M, Krzeminski TF. Comparison of thiopental, urethane, and pentobarbital in the study of experimental cardiology in rats in vivo. J Cardiovasc Pharmacol 2010; 56:38-44.
20. Parker JL, Adams HR. Drugs and the heart muscle. J Am Vet Met Assoc 1977; 171:89-94.
21. Bachmann A, Mueller S, Kopp K, et al. Inhibition of cardiac potassium currents by pentobarbital. Naunyn Schmiedebergs Arch Pharmacol 2002; 365:29-37. (Pubitemid 34045237)