메뉴 건너뛰기




Volumn 86, Issue 2, 1997, Pages 410-419

Stereospecific effect of bupivacaine isomers on atrioventricular conduction in the isolated perfused guinea pig heart

Author keywords

Anesthetics, local: bupivacaine; stereoisomers; Heart: AV conduction; contractility; coronary flow; isolated; oxygen consumption; rate

Indexed keywords

BUPIVACAINE; KETAMINE; LOCAL ANESTHETIC AGENT; RINGER SOLUTION;

EID: 0031043846     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199702000-00016     Document Type: Article
Times cited : (78)

References (40)
  • 3
    • 0021635534 scopus 로고
    • Convulsions and ventricular tachycardia from bupivacaine with epinephrine: Successful resuscitation
    • Mallampati SR, Liu PL, Knapp RM: Convulsions and ventricular tachycardia from bupivacaine with epinephrine: Successful resuscitation. Anesth Analg 1984; 63:856-9
    • (1984) Anesth Analg , vol.63 , pp. 856-859
    • Mallampati, S.R.1    Liu, P.L.2    Knapp, R.M.3
  • 4
    • 0017259901 scopus 로고
    • Topical anesthesia and topical toxicity of bupivacaine combined with hydroxypolyethoxydodecane
    • Aberg G, Adler G: Topical anesthesia and topical toxicity of bupivacaine combined with hydroxypolyethoxydodecane. Arzneimittelforschung 1976; 26:78-80
    • (1976) Arzneimittelforschung , vol.26 , pp. 78-80
    • Aberg, G.1    Adler, G.2
  • 5
    • 0015462529 scopus 로고
    • Mechanical and electrophysiological effects of some local anaesthetic agents and their isomere on the rat portal vein
    • Aberg G, Wahlstrom B: Mechanical and electrophysiological effects of some local anaesthetic agents and their isomere on the rat portal vein. Acta Pharmacol Toxicol 1972; 31:255-66
    • (1972) Acta Pharmacol Toxicol , vol.31 , pp. 255-266
    • Aberg, G.1    Wahlstrom, B.2
  • 6
    • 0015464306 scopus 로고
    • Toxicological and local anaesthetic effects of optically active isomers of two local anesthetic compounds
    • Aberg G: Toxicological and local anaesthetic effects of optically active isomers of two local anesthetic compounds. Acta Pharmacol Toxicol 1972; 31:273-86
    • (1972) Acta Pharmacol Toxicol , vol.31 , pp. 273-286
    • Aberg, G.1
  • 7
    • 0023731286 scopus 로고
    • Primary evaluation of the local anaesthetic properties of the amino amide agent ropivacaine (LEA 103)
    • Akerman B, Hellberg IB, Trossvik C: Primary evaluation of the local anaesthetic properties of the amino amide agent ropivacaine (LEA 103). Acta Anaesthesiol Scand 1988; 32:571-8
    • (1988) Acta Anaesthesiol Scand , vol.32 , pp. 571-578
    • Akerman, B.1    Hellberg, I.B.2    Trossvik, C.3
  • 8
  • 9
    • 0025099466 scopus 로고
    • Cardiac electrophysiologic properties of bupivacaine and lidocaine compared with those of ropivacaine, a new amide local anesthetic
    • Moller R, Covino BG: Cardiac electrophysiologic properties of bupivacaine and lidocaine compared with those of ropivacaine, a new amide local anesthetic. ANESTHESIOLOGY 1990; 72:322-9
    • (1990) Anesthesiology , vol.72 , pp. 322-329
    • Moller, R.1    Covino, B.G.2
  • 10
    • 0022589565 scopus 로고
    • Cardiovascular toxicity of local anesthetics: An alternative hypothesis
    • Thomas RD, Behbehani MM, Coyle DE, Denson DD: Cardiovascular toxicity of local anesthetics: An alternative hypothesis. Anesth Analg 1986; 65:444-50
    • (1986) Anesth Analg , vol.65 , pp. 444-450
    • Thomas, R.D.1    Behbehani, M.M.2    Coyle, D.E.3    Denson, D.D.4
  • 11
    • 0027049954 scopus 로고
    • Enantiomer-specific effects of an intravenously administered arrhythmogenic dose of bupivacaine on neurons of the nucleus tractus solitarius and the cardiovascular system in the anesthetized rat
    • Denson DD, Behbehani MM, Gregg RV: Enantiomer-specific effects of an intravenously administered arrhythmogenic dose of bupivacaine on neurons of the nucleus tractus solitarius and the cardiovascular system in the anesthetized rat. Reg Anesth 1992; 17:311-6
    • (1992) Reg Anesth , vol.17 , pp. 311-316
    • Denson, D.D.1    Behbehani, M.M.2    Gregg, R.V.3
  • 12
    • 0028335746 scopus 로고
    • Lack of stereospecific effects of isoflurane and desflurane in isolated guinea pig hearts
    • Graf BM, Boban M, Stowe DF, Kampine JP, Bosnjak ZJ: Lack of stereospecific effects of isoflurane and desflurane in isolated guinea pig hearts. ANESTHESIOLOGY 1994; 81:129-36
    • (1994) Anesthesiology , vol.81 , pp. 129-136
    • Graf, B.M.1    Boban, M.2    Stowe, D.F.3    Kampine, J.P.4    Bosnjak, Z.J.5
  • 13
    • 0029018238 scopus 로고
    • Ketamine has stereospecific effects in the isolated perfused guinea pig heart
    • Graf BM, Vicenzi M, Bosnjak ZJ, Martin E, Stowe DF: Ketamine has stereospecific effects in the isolated perfused guinea pig heart. ANESTHESIOLOGY 1995; 82:1426-37
    • (1995) Anesthesiology , vol.82 , pp. 1426-1437
    • Graf, B.M.1    Vicenzi, M.2    Bosnjak, Z.J.3    Martin, E.4    Stowe, D.F.5
  • 14
    • 0026510636 scopus 로고
    • Direct comparative effects of isoflurane and desflurane in isolated guinea pig hearts
    • Boban M, Stowe DF, Buljubasic N, Kampine JP, Bosnjak ZJ: Direct comparative effects of isoflurane and desflurane in isolated guinea pig hearts. ANESTHESIOLOGY 1992; 76:775-80
    • (1992) Anesthesiology , vol.76 , pp. 775-780
    • Boban, M.1    Stowe, D.F.2    Buljubasic, N.3    Kampine, J.P.4    Bosnjak, Z.J.5
  • 15
    • 0025815241 scopus 로고
    • Direct comparative effects of halothane, enflurane, and isoflurane on oxygen supply and demand in isolated hearts
    • Stowe DF, Marjic J, Bosnjak ZJ, Kampine JP: Direct comparative effects of halothane, enflurane, and isoflurane on oxygen supply and demand in isolated hearts. ANESTHESIOLOGY 1991; 74:1087-95
    • (1991) Anesthesiology , vol.74 , pp. 1087-1095
    • Stowe, D.F.1    Marjic, J.2    Bosnjak, Z.J.3    Kampine, J.P.4
  • 16
    • 0023891102 scopus 로고
    • Effects of halothane with and without histamine and/or epinephrine on automaticity, intracardiac conduction times and development of dysrhythmias in the isolated guinea pig heart
    • Stowe DF, Bosnjak ZJ, Marijic J, Kampine JP: Effects of halothane with and without histamine and/or epinephrine on automaticity, intracardiac conduction times and development of dysrhythmias in the isolated guinea pig heart. ANESTHESIOLOGY 1988; 68:695-706
    • (1988) Anesthesiology , vol.68 , pp. 695-706
    • Stowe, D.F.1    Bosnjak, Z.J.2    Marijic, J.3    Kampine, J.P.4
  • 17
    • 0014643860 scopus 로고
    • Stereoisomerism and differential activity in excitation block by local anesthetics
    • Akerman B, Camougis G, Sandberg RV: Stereoisomerism and differential activity in excitation block by local anesthetics. Eur J Pharmacol 1969; 8:337-47
    • (1969) Eur J Pharmacol , vol.8 , pp. 337-347
    • Akerman, B.1    Camougis, G.2    Sandberg, R.V.3
  • 18
    • 0015829328 scopus 로고
    • Uptake and retention of the enantiomers of a local anesthetic in isolated nerve in relation to different degrees of blocking of nervous conduction
    • Akerman B: Uptake and retention of the enantiomers of a local anesthetic in isolated nerve in relation to different degrees of blocking of nervous conduction. Acta Pharacol Toxicol 1973; 32:225-36
    • (1973) Acta Pharacol Toxicol , vol.32 , pp. 225-236
    • Akerman, B.1
  • 19
    • 0024259977 scopus 로고
    • Determinants of stereospecific binding of type 1 antiarrhythmic drugs to cardiac sodium channels
    • Jill RJ, Diff HJ, Sheldon RS: Determinants of stereospecific binding of type 1 antiarrhythmic drugs to cardiac sodium channels. Mol Pharmacol 1988; 34:659-63
    • (1988) Mol Pharmacol , vol.34 , pp. 659-663
    • Jill, R.J.1    Diff, H.J.2    Sheldon, R.S.3
  • 20
    • 0022541982 scopus 로고
    • Comparison of lidocaine and bupivacaine depression of sinoatrial nodal activity during hypoxia and acidosis in adult and neonatal guinea pigs
    • Bosnjak ZJ, Stowe DF, Kampine JP: Comparison of lidocaine and bupivacaine depression of sinoatrial nodal activity during hypoxia and acidosis in adult and neonatal guinea pigs. Anesth Analg 1986; 65:911-7
    • (1986) Anesth Analg , vol.65 , pp. 911-917
    • Bosnjak, Z.J.1    Stowe, D.F.2    Kampine, J.P.3
  • 21
    • 0021849763 scopus 로고
    • Cardiac electrophysiologic and hemodynamic effects related to plasma levels of bupivacaine in the dog
    • Hotvedt R, Refsum H, Helgesen KG: Cardiac electrophysiologic and hemodynamic effects related to plasma levels of bupivacaine in the dog. Anesth Analg 1985; 64:388-94
    • (1985) Anesth Analg , vol.64 , pp. 388-394
    • Hotvedt, R.1    Refsum, H.2    Helgesen, K.G.3
  • 22
    • 0021990445 scopus 로고
    • Successful cardiovascular resuscitation after massive intravenous bupivacaine overdosage in anesthetized dogs
    • Kasten G, Martin S: Successful cardiovascular resuscitation after massive intravenous bupivacaine overdosage in anesthetized dogs. Anesth Analg 1985; 64:491-7
    • (1985) Anesth Analg , vol.64 , pp. 491-497
    • Kasten, G.1    Martin, S.2
  • 23
    • 0019487245 scopus 로고
    • Effects of bupivacaine and lidocaine on AV conduction in the isolated rat heart: Modification by hyperkalemia
    • Komai H, Rusy BF: Effects of bupivacaine and lidocaine on AV conduction in the isolated rat heart: Modification by hyperkalemia. ANESTHESIOLOGY 1981; 55:281-5
    • (1981) Anesthesiology , vol.55 , pp. 281-285
    • Komai, H.1    Rusy, B.F.2
  • 24
    • 0027192954 scopus 로고
    • Potassium channel openers attenuate atrioventricular block by bupivacaine in isolated hearts
    • Boban M, Stowe DF, Gross GJ, Pieper GM, Kampine JP, Bosnjak ZJ: Potassium channel openers attenuate atrioventricular block by bupivacaine in isolated hearts. Anesth Analg 1993; 76:1259-65
    • (1993) Anesth Analg , vol.76 , pp. 1259-1265
    • Boban, M.1    Stowe, D.F.2    Gross, G.J.3    Pieper, G.M.4    Kampine, J.P.5    Bosnjak, Z.J.6
  • 25
    • 0023874612 scopus 로고
    • Cardiac electrophysiologic effects of lidocaine and bupivacaine
    • Moller RA, Covino BG: Cardiac electrophysiologic effects of lidocaine and bupivacaine. Anesth Analg 1988; 67:107-14
    • (1988) Anesth Analg , vol.67 , pp. 107-114
    • Moller, R.A.1    Covino, B.G.2
  • 26
    • 0022647879 scopus 로고
    • Cardiotoxicity of local anesthetic agents
    • Reiz S, Nath S: Cardiotoxicity of local anesthetic agents. Br J Anaesth 1986; 58:736-46
    • (1986) Br J Anaesth , vol.58 , pp. 736-746
    • Reiz, S.1    Nath, S.2
  • 27
    • 0027235743 scopus 로고
    • Myocardial uptake of bupivacaine: II. Pharmacokinetics and pharmacodynamics of bupivacaine enantiomers in the isolated perfused rabbit heart
    • Mazoit JX, Boico O, Samil K: Myocardial uptake of bupivacaine: II. Pharmacokinetics and pharmacodynamics of bupivacaine enantiomers in the isolated perfused rabbit heart. Anesth Analg 1993; 77:477-82
    • (1993) Anesth Analg , vol.77 , pp. 477-482
    • Mazoit, J.X.1    Boico, O.2    Samil, K.3
  • 28
    • 0022460362 scopus 로고
    • Comparison of resuscitation of sheep and dogs after bupivacaine-induced cardiovascular collapse
    • Kasten GW, Martin ST: Comparison of resuscitation of sheep and dogs after bupivacaine-induced cardiovascular collapse. Anesth Analg 1986; 61:1029-32
    • (1986) Anesth Analg , vol.61 , pp. 1029-1032
    • Kasten, G.W.1    Martin, S.T.2
  • 29
    • 0022447743 scopus 로고
    • Depression of myocardial contractility in vitro by bupivacaine, etidocaine, and lidocaine
    • Lynch C III: Depression of myocardial contractility in vitro by bupivacaine, etidocaine, and lidocaine. Anesth Analg 1986; 65:551-9
    • (1986) Anesth Analg , vol.65 , pp. 551-559
    • Lynch C. III1
  • 30
    • 0023204899 scopus 로고
    • Bupivacaine and lidocaine blockade of calcium-mediated slow action potentials in guinea pig ventricular muscle
    • Coyle DE, Sperelakis N: Bupivacaine and lidocaine blockade of calcium-mediated slow action potentials in guinea pig ventricular muscle. J Pharmacol Exp Ther 1987; 242:1001-5
    • (1987) J Pharmacol Exp Ther , vol.242 , pp. 1001-1005
    • Coyle, D.E.1    Sperelakis, N.2
  • 31
    • 0023791644 scopus 로고
    • Effects of bupivacaine on membrane currents of guinea-pig ventricular myocytes
    • Sanchez-Chapula J: Effects of bupivacaine on membrane currents of guinea-pig ventricular myocytes. Eur J Pharmacol 1988; 156:303-8
    • (1988) Eur J Pharmacol , vol.156 , pp. 303-308
    • Sanchez-Chapula, J.1
  • 32
    • 0023830165 scopus 로고
    • Bupivacaine is an effective potassium channel blocker in heart
    • Courtney KR, Kendig JJ: Bupivacaine is an effective potassium channel blocker in heart. Biochim Biophys Acts 1988; 959:163-6
    • (1988) Biochim Biophys Acts , vol.959 , pp. 163-166
    • Courtney, K.R.1    Kendig, J.J.2
  • 33
    • 0025599377 scopus 로고
    • Bupivacaine inhibits the transient outward K+ current but not the inward rectifier in rat ventricular myocytcs
    • Castle NA: Bupivacaine inhibits the transient outward K+ current but not the inward rectifier in rat ventricular myocytcs. J Pharmacol Exp Ther 1990; 255:1038-46
    • (1990) J Pharmacol Exp Ther , vol.255 , pp. 1038-1046
    • Castle, N.A.1
  • 35
    • 0017726385 scopus 로고
    • Time and voltage dependent interactions of antiarrhythmic drugs with cardiac sodium channels
    • Hondeghem L, Katzung B: Time and voltage dependent interactions of antiarrhythmic drugs with cardiac sodium channels. Biochim Acta 1977; 472:373-98
    • (1977) Biochim Acta , vol.472 , pp. 373-398
    • Hondeghem, L.1    Katzung, B.2
  • 36
    • 0021940537 scopus 로고
    • Mechanism for bupivacaine depression of cardiac conduction: Fast block of sodium channels during the action potential with slow recovery from block during diastole
    • Clarkson CW, Hondeghem LM: Mechanism for bupivacaine depression of cardiac conduction: Fast block of sodium channels during the action potential with slow recovery from block during diastole. ANESTHESIOLOGY 1985; 62:396-405
    • (1985) Anesthesiology , vol.62 , pp. 396-405
    • Clarkson, C.W.1    Hondeghem, L.M.2
  • 37
    • 0028817743 scopus 로고
    • Stereoselective block of sodium channels by bupivacaine in guinea pig ventricular myocytes
    • Valenzuela C, Snyders DJ, Bennett PB, Tamargo J, Hontleghem LM: Stereoselective block of sodium channels by bupivacaine in guinea pig ventricular myocytes. Circulation 1995; 92:3014-24
    • (1995) Circulation , vol.92 , pp. 3014-3024
    • Valenzuela, C.1    Snyders, D.J.2    Bennett, P.B.3    Tamargo, J.4    Hontleghem, L.M.5
  • 38
    • 0342806721 scopus 로고
    • Stereoselectivity of bupivacaine on cardiac Na+ channels is dependent on cyclic adenosine monophosphate
    • Graf BM, Bosnjak ZJ, Martin E, Stowe DF, Kwok WM: Stereoselectivity of bupivacaine on cardiac Na+ channels is dependent on cyclic adenosine monophosphate (abstract). ANESTHESIOLOGY 1995; 83(Suppl):A304
    • (1995) Anesthesiology , vol.83 , Issue.SUPPL.
    • Graf, B.M.1    Bosnjak, Z.J.2    Martin, E.3    Stowe, D.F.4    Kwok, W.M.5
  • 40
    • 0025860073 scopus 로고
    • Stereoselective effects of enantiomers of bupivacaine on the electrophysiological properties of guinea pig papillary muscle
    • Vanhoutte F, Vereecke J, Verbeke N, Carmeliet E: Stereoselective effects of enantiomers of bupivacaine on the electrophysiological properties of guinea pig papillary muscle. Br J Pharmacol 1991; 103:1275-81
    • (1991) Br J Pharmacol , vol.103 , pp. 1275-1281
    • Vanhoutte, F.1    Vereecke, J.2    Verbeke, N.3    Carmeliet, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.