Long-chain polyunsaturated fatty acid supplementation in infancy reduces heart rate and positively affects distribution of attention

Pediatric Research

Volumn 70, Issue 4, 2011, Pages 406-410

  Colombo, John ^a   Carlson, Susan E ^b   Cheatham, Carol L ^c   Fitzgerald Gustafson, Kathleen M ^b   Kepler, Amy ^b   Doty, Tasha ^b  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; POLYUNSATURATED FATTY ACID;

ARTICLE; ATTENTION; CARDIOVASCULAR RESPONSE; CHILD BEHAVIOR; COGNITION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; HABITUATION; HEART RATE; HUMAN; HUMAN EXPERIMENT; LEARNING; LIPID COMPOSITION; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ANIMALS; ATTENTION; DIETARY SUPPLEMENTS; DOCOSAHEXAENOIC ACIDS; DOUBLE-BLIND METHOD; FATTY ACIDS, UNSATURATED; HEART RATE; HUMANS; INFANT; INFANT FORMULA; NEUROPSYCHOLOGICAL TESTS; PROSPECTIVE STUDIES;

EID: 80052605652     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/PDR.0b013e31822a59f5     Document Type: Article

References (48)

1. Clandinin MT, Chappell JE, Leong S, Heim T, Swyer PR, Chance GW 1980 Extra-uterine fatty-acid accretion in infant brain: implications for fatty-acid requirements. Early Hum Dev 4:131-138 (Pubitemid 10064581)
2. Martínez M, Mougan I 1998 Fatty acid composition of human brain phospholipids during normal development. J Neurochem 71:2528-2533 (Pubitemid 28531264)
3. Farquharson J, Jamieson EC, Abbasi KA, Patrick WJ, Logan RW, Cockburn F 1995 Effect of diet on the fatty-acid composition of the major phospholipids of infant cerebral cortex. Arch Dis Child 72:198-203
4. Makrides M, Neumann MA, Byard RW, Simmer K, Gibson RA 1994 Fatty-acid composition of brain, retina, and erythrocytes in breast-fed and formula-fed infants. Am J Clin Nutr 60:189-194 (Pubitemid 24233184)
5. Birch EE, Hoffman DR, Uauy R, Birch DG, Prestidge C 1998 Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatr Res 44:201-209 (Pubitemid 28347897)
6. Carlson SE, Ford AJ, Werkman SH, Peeples JM, Koo WW 1996 Visual acuity and fatty acid status of term infants fed human milk and formulas with and without docosahexaenoate and arachidonate from egg yolk lecithin. Pediatr Res 39:882-888 (Pubitemid 26130032)
7. Auestad N, Montalto MB, Hall RT, Fitzgerald KM, Wheeler RE, Connor WE, Neuringer M, Connor SL, Taylor JA, Hartmann EE 1997 Visual acuity, erythrocyte fatty acid composition, and growth in term infants fed formulas with long chain polyunsaturated fatty acids for one year. Pediatr Res 41:1-10 (Pubitemid 27008628)
8. Jensen CL, Prager TC, Fraley JK, Chen HM, Anderson RE, Heird WC 1997 Effect of dietary linoleic/alpha-linolenic acid ratio on growth and visual function of term infants. J Pediatr 131:200-209 (Pubitemid 27495237)
9. Innis SM, Akrabawi SS, Diersen-Schade DA, Dobson MV, Guy DG 1997 Visual acuity and blood lipids in term infants fed human milk or formulae. Lipids 32:63-72 (Pubitemid 27057302)
10. Carrié I, Clément M, De Javel D, Francès H, Bourre JM 1999 Learning deficits in first generation OF1 mice deficient in (n-3) polyunsaturated fatty acids do not result from visual alteration. Neurosci Lett 266:69-72 (Pubitemid 29219758)
11. Wainwright PE, Huang YS, Coscina DV, Levesque S, McCutcheon D 1994 Brain-effects and behavioral-effects of dietary n-3 deficiency in mice: a 3-generational study. Dev Psychobiol 27:467-487 (Pubitemid 2162190)
12. Stevens LJ, Zentall SS, Abate ML, Kuczek T, Burgess JR 1996 Omega-3 fatty acids in boys with behavior, learning, and health problems. Physiol Behav 59:915-920 (Pubitemid 26110718)
13. Willatts P, Forsyth JS 2000 The role of long-chain polyunsaturated fatty acids in infant cognitive development. Prostaglandins Leukot Essent Fatty Acids 63:95-100
14. Agostoni C, Trojan S, Bellu R, Giovannini M 1995 Neurodevelopmental quotient of healthy term infants at 4 months and feeding practice: the role of long-chain polyunsaturated fatty-acids. Pediatr Res 38:262-266
15. Agostoni C, Trojan S, Bellu R, Riva E, Bruzzese MG, Giovannini M 1997 Developmental quotient at 24 months and fatty acid composition of diet in early infancy: a follow up study. Arch Dis Child 76:421-424 (Pubitemid 27261857)
16. Birch EE, Garfield S, Hoffman DR, Uauy R, Birch DG 2000 A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants. Dev Med Child Neurol 42:174-181 (Pubitemid 30145332)
17. Birch EE, Garfield S, Castaneda Y, Hughbanks-Wheaton D, Uauy R, Hoffman D 2007 Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula. Early Hum Dev 83:279-284 (Pubitemid 46561172)
18. Makrides M, Neumann MA, Simmer K, Gibson RA 2000 A critical appraisal of the role of dietary long-chain polyunsaturated fatty acids on neural indices of term infants: a randomized, controlled trial. Pediatrics 105:32-38 (Pubitemid 30035715)
19. Auestad N, Scott DT, Janowsky JS, Jacobsen C, Carroll RE, Montalto MB, Halter R, Qiu W, Jacobs JR, Connor WE, Connor SL, Taylor JA, Neuringer M, Fitzgerald KM, Hall RT 2003 Visual, cognitive, and language assessments at 39 months: a follow-up study of children fed formulas containing long-chain polyunsaturated fatty acids to 1 year of age. Pediatrics 112:e177-e183
20. Simmer K, Patole SK, Rao SC 2008 Longchain polyunsaturated fatty acid supplementation in infants born at term. Cochrane Database Syst Rev: CD000376
21. Beyerlein A, Hadders-Algra M, Kennedy K, Fewtrell M, Singhal A, Rosenfeld E, Lucas A, Bouwstra H, Koletzko B, von Kries R 2010 Infant formula supplementation with long-chain polyunsaturated fatty acids has no effect on Bayley developmental scores at 18 months of age-IPD meta-analysis of 4 large clinical trials. J Pediatr Gastroenterol Nutr 50:79-84
22. Colombo J 2002 Infant attention grows up: the emergence of a developmental cognitive neuroscience perspective. Curr Dir Psychol Sci 11:196-200 (Pubitemid 36027872)
23. Bornstein MH, Sigman MD 1986 Continuity in mental development from infancy. Child Dev 57:251-274
24. Colombo J 1993 Infant Cognition: Predicting Later Intellectual Functioning. Sage Publications, Newbury Park, pp. 30-81
25. Colombo J, Kannass KN, Shaddy DJ, Kundurthi S, Maikranz JM, Anderson CJ, Blaga OM, Carlson SE 2004 Maternal DHA and the development of attention in infancy and toddlerhood. Child Dev 75:1254-1267 (Pubitemid 39137766)
26. Colombo J, Mitchell DW 2009 Infant visual habituation. Neurobiol Learn Mem 92:225-234
27. Casey BJ, Richards JE 1988 Sustained visual-attention in young infants measured with an adapted version of the visual preference paradigm. Child Dev 59:1514-1521
28. McLennan PL, Owen AJ, Slee EL, Theiss ML 2007 Myocardial function, ischaemia and n-3 polyunsaturated fatty acids: a membrane basis. J Cardiovasc Med (Hager-stown) 8:S15-S18 (Pubitemid 47429075)
29. Christensen JH, Schmidt EB 2007 Autonomic nervous system, heart rate variability and n-3 fatty acids. J Cardiovasc Med (Hagerstown) 8:S19-S22 (Pubitemid 47429076)
30. Birch EE, Carlson SE, Hoffman DR, Fitzgerald-Gustafson KM, Fu VL, Drover JR, Castaneda YS, Minns L, Wheaton DK, Mundy D, Marunycz J, Diersen-Schade DA 2010 The DIAMOND (DHA Intake And Measurement Of Neural Development) Study: a double-masked, randomized controlled clinical trial of the maturation of infant visual acuity as a function of the dietary level of docosahexaenoic acid. Am J Clin Nutr 91:848-859
31. Colombo J, Shaddy DJ, Richman WA, Maikranz JM, Blaga OM 2004 The developmental course of habituation in infancy and preschool outcome. Infancy 5:1-38 (Pubitemid 40259882)
32. Colombo J, Mitchell DW, O'Brien M, Horowitz FD 1987 The stability of visual habituation during the first year of life. Child Dev 58:474-487
33. Colombo J, Mitchell DW 1990 Individual differences in early visual attention: fixation time and information processing. In: Colombo J, Fagen J (eds) Individual Differences in Infancy: Reliability, Stability, Prediction. Lawrence Erlbaum Associates, Hillsdale, NJ, pp 193-227
34. Colombo J, Horowitz FD 1985 A parametric study of the infant control procedure. Infant Behav Dev 8:117-121
35. Richards JE 1985 The development of sustained visual-attention in infants from 14 to 26 weeks of age. Psychophysiology 22:409-416 (Pubitemid 15010777)
36. Carlson SE, Werkman SH 1996 A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until two months. Lipids 31:85-90 (Pubitemid 26023682)
37. Richards JE 1987 Infant visual sustained attention and respiratory sinus arrhythmia. Child Dev 58:488-496
38. Colombo J, Richman WA, Shaddy DJ, Greenhoot AF, Maikranz JM 2001 Heart rate-defined phases of attention, look duration, and infant performance in the paired-comparison paradigm. Child Dev 72:1605-1616 (Pubitemid 33602778)
39. Colombo J, Shaddy DJ, Anderson CJ, Gibson LJ, Blaga OM, Kannass KN 2010 What habituates in infant visual habituation? A psychophysiological analysis. Infancy 15:107-124
40. Colombo J, Shaddy DJ, Blaga OM, Anderson CJ, Kannass KN, Richman WA 2009 Early attentional predictors of vocabulary in childhood. In: Colombo J, McCardle P, Freund L (eds) Infant Pathways to Language: Methods, Models, and Research Directions. Lawrence Erlbaum Associates, New York, NY, pp 143-167
41. Calder PC 2004 n-3 fatty acids and cardiovascular disease: evidence explained and mechanisms explored. Clin Sci 107:1-11 (Pubitemid 38932191)
42. von Schacky C 2004 Omega-3 fatty acids and cardiovascular disease. Curr Opin Clin Nutr Metab Care 7:131-136 (Pubitemid 40340674)
43. Mozaffarian D, Stein PK, Prineas RJ, Siscovick DS 2008 Dietary fish and omega-3 fatty acid consumption and heart rate variability in US adults. Circulation 117:1130-1137 (Pubitemid 351544069)
44. Mozaffarian D, Prineas RJ, Stein PK, Siscovick DS 2006 Dietary fish and n-3 fatty acid intake and cardiac electrocardiographic parameters in humans. J Am Coll Cardiol 48:478-484 (Pubitemid 44093963)
45. Lauritzen L, Christensen JH, Damsgaard CT, Michaelsen KF 2008 The effect of fish oil supplementation on heart rate in healthy Danish infants. Pediatr Res 64:610-614
46. Peoples GE, McLennan PL, Howe PR, Groeller H 2008 Fish oil reduces heart rate and oxygen consumption during exercise. J Cardiovasc Pharmacol 52:540-547
47. Gustafson KM, Colombo J, Carlson SE 2008 Docosahexaenoic acid and cognitive function: is the link mediated by the autonomic nervous system? Prostaglandins Leukot Essent Fatty Acids 79:135-140
48. Hibbeln JR, Ferguson TA, Blasbalg TL 2006 Omega-3 fatty acid deficiencies in neurodevelopment, aggression and autonomic dysregulation: opportunities for intervention. Int Rev Psychiatry 18:107-118 (Pubitemid 43791674)