Osteoinductive and anti-inflammatory effect of royal jelly on periodontal ligament cells

Biomedical Research

Volumn 32, Issue 4, 2011, Pages 285-291

  Yanagita, Manabu ^a   Kojima, Yuko ^a   Mori, Kenta ^a   Yamada, Satoru ^a   Murakami, Shinya ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MESSENGER RNA; ROYAL JELLY;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE MINERALIZATION; CELL CLONE; CELL LINEAGE; CELL TRANSFORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; DRUG MECHANISM; GENE; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; ODONTOBLAST; OSTEOBLAST; OSTEOCALCIN GENE; OSTEOPONTIN GENE; OSTERIX GENE; PERIODONTAL LIGAMENT; PORPHYROMONAS GINGIVALIS; TOOTH DEVELOPMENT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CYTOKINES; FATTY ACIDS; GENE EXPRESSION REGULATION; INTERCELLULAR ADHESION MOLECULE-1; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; OSTEOCALCIN; OSTEOGENESIS; OSTEOPONTIN; PERIODONTAL LIGAMENT; PORPHYROMONAS GINGIVALIS; RATS; RNA, MESSENGER; TRANSCRIPTION FACTORS;

BACTERIA (MICROORGANISMS); PORPHYROMONAS GINGIVALIS; RATTUS;

EID: 80052599618     PISSN: 03886107     EISSN: 1880313X     Source Type: Journal    
DOI: 10.2220/biomedres.32.285     Document Type: Article

References (28)

1. Akira S, Taga T and Kishimoto T (1993) Interleukin-6 in biology and medicine. Adv Immunol 54, 1-78.
2. Arceo N, Sauk J, Moehring J, Foster R and Somerman M (1991) Human periodontal cells initiate mineral-like nodules in vitro. J Periodontol 62, 499-503.
3. Bincoletto C, Eberlin S, Figueiredo C, Luengo M and Queiroz M (2005) Effects produced by Royal Jelly on haematopoiesis: relation with host resistance against Ehrlich ascites tumour challenge. Int Immunopharmacol 5, 679-688.
4. Fujiwara S, Imai J, Fujiwara M, Yaeshima T, Kawashima T and Kobayashi K (1990) A potent antibacterial protein in royal jelly. Purification and determination of the primary structure of royalisin. J Biol Chem 265, 11333-11337.
5. Hattori N, Nomoto H, Mishima S, Inagaki S, Goto M, Sako M and Furukawa S (2006) Identification of AMP N1-oxide in royal jelly as a component neurotrophic toward cultured rat pheochromocytoma PC12 cells. Biosci Biotechnol Biochem 70, 897-906.
6. Hayashi J, Saito I, Ishikawa I and Miyasaka N (1994) Effects of cytokines and periodontopathic bacteria on the leukocyte function-associated antigen 1/intercellular adhesion molecule 1 pathway in gingival fibroblasts in adult periodontitis. Infect Immun 62, 5205-5212.
7. Hidaka S, Okamoto Y, Uchiyama S, Nakatsuma A, Hashimoto K, Ohnishi S and Yamaguchi M (2006) Royal jelly prevents osteoporosis in rats: beneficial effects in ovariectomy model and in bone tissue culture model. Evid Based Complement Alternat Med 3, 339-348.
8. Joe BH, Borke JL, Keskintepe M, Hanes PJ, Mailhot JM and Singh BB (2001) Interleukin-1beta regulation of adhesion molecules on human gingival and periodontal ligament fibroblasts. J Periodontol 72, 865-870.
9. Kawai T, Eisen-Lev R, Seki M, Eastcott JW, Wilson ME and Taubman MA (2000) Requirement of B7 costimulation for Th1-mediated inflammatory bone resorption in experimental periodontal disease. J Immunol 164, 2102-2109.
10. Kinane D (2001) Causation and pathogenesis of periodontal disease. Periodontol 2000 25, 8-20.
11. Kohno K, Okamoto I, Sano O, Arai N, Iwaki K, Ikeda M and Kurimoto M (2004) Royal jelly inhibits the production of proinflammatory cytokines by activated macrophages. Biosci Biotechnol Biochem 68, 138-145.
12. Lee S, Kim K and Choi B (2005) Upregulation of intercellular adhesion molecule 1 and proinflammatory cytokines by the major surface proteins of Treponema maltophilum andTreponema lecithinolyticum, the phylogenetic group IV oral spirochetes associated with periodontitis and endodontic infections. Infect Immun 73, 268-276.
13. Lerner U (2006) Inflammation-induced bone remodeling in periodontal disease and the influence of post-menopausal osteoporosis. J Dent Res 85, 596-607.
14. Mayrand D and Holt SC (1988) Biology of asaccharolytic black-pigmented Bacteroides species. Microbiol Rev 52, 134-152.
15. Mishima S, Suzuki K, Isohama Y, Kuratsu N, Araki Y, Inoue M and Miyata T (2005) Royal jelly has estrogenic effects in vitro and in vivo. J Ethnopharmacol 101, 215-220.
16. Murakami S, Hashikawa T, Saho T, Takedachi M, Nozaki T, Shimabukuro Y and Okada H (2001) Adenosine regulates the IL-1 beta-induced cellular functions of human gingival fibroblasts. Int Immunol 13, 1533-1540.
17. Nagai T, Nagashima T, Myoda T and Inoue R (2004) Preparation and functional properties of extracts from bee bread. Nahrung 48, 226-229.
18. Nagatomo K, Komaki M, Sekiya I, Sakaguchi Y, Noguchi K, Oda S, Muneta T and Ishikawa I (2006) Stem cell properties of human periodontal ligament cells. J Periodontal Res 41, 303-310.
19. Narita Y, Nomura J, Ohta S, Inoh Y, Suzuki KM, Araki Y, Okada S, Matsumoto I, Isohama Y, Abe K, Miyata T and Mishima S (2006) Royal jelly stimulates bone formation: physiologic and nutrigenomic studies with mice and cell lines. Biosci Biotechnol Biochem 70, 2508-2514.
20. Okamoto I, Taniguchi Y, Kunikata T, Kohno K, Iwaki K, Ikeda M and Kurimoto M (2003) Major royal jelly protein 3 modulates immune responses in vitro and in vivo. Life Sci 73, 2029-2045.
21. Seo B, Miura M, Gronthos S, Bartold P, Batouli S, Brahim J, Young M, Robey P, Wang C and Shi S (2004) Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 364, 149-155.
22. Shinoda M, Nakajin S, Oikawa T, Sato K, Kamogawa A and Akiyama Y (1978) [Biochemical studies on vasodilative factor in royal jelly (author's transl)]. Yakugaku Zasshi 98, 139-145. (In Japanease)
23. Shu L, Guan SM, Fu SM, Guo T, Cao M and Ding Y (2008) Estrogen modulates cytokine expression in human periodontal ligament cells. J Dent Res 87, 142-147.
24. Socransky S, Smith C and Haffajee A (2002) Subgingival microbial profiles in refractory periodontal disease. J Clin Periodontol 29, 260-268.
25. Vittek J (1995) Effect of royal jelly on serum lipids in experimental animals and humans with atherosclerosis. Experientia 51, 927-935.
26. Yamada S, Tomoeda M, Ozawa Y, Yoneda S, Terashima Y, Ikezawa K, Ikegawa S, Saito M, Toyosawa S and Murakami S (2007) PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization. J Biol Chem 282, 23070-23080.
27. Yamaji Y, Kubota T, Sasaguri K, Sato S, Suzuki Y, Kumada H and Umemoto T (1995) Inflammatory cytokine gene expression in human periodontal ligament fibroblasts stimulated with bacterial lipopolysaccharides. Infect Immun 63, 3576-3581.
28. Yanagita M, Kojima Y, Kawahara T, Kajikawa T, Oohara H, Takedachi M, Yamada S and Murakami S (2010) Suppressive effects of nicotine on the cytodifferentiation of murine periodontal ligament cells. Oral Diseases 16, 812-817.